Key Rearch and Development projects in Shaanxi Province(2019SF-084).
Objective:To investigate the effect ofα1-antitrypsin combined with bone marrow mesenchymal stem cells on retinopathy in diabetic rats and its mechanism.Methods:A model of diabetic retinopathy was established by intra...
Background:As an acute phase protein,α1-antitrypsin (AAT) has been extensively studied in acute coronary syndrome,but it is unclear whether a relationship exists between AAT and stable angina pectoris (SAP).The purpo...
Although islet transplantation for individuals with type I diabetes has been shown to yield superior blood glucose control, it remains inadequate for long-term control. This is partly due to islet injuries and stresse...
Project supported by the National Natural Science Foundationof China; No 30140023;and the Li KaShing Foundation; HongKong; China. No C0200001
AIM: To investigate the ability of natural chymase inhibitors to modulate histamine release from human mast cells. METHODS: Enzymatically dispersed cells from human lung, tonsil, and skin were challenged with anti-Ig...
the Scientific Foundation of the Ministry of Health (No: 98-1-150)
Objective To investigate whether pretreatment with α1,-antitrypsin (AAT) can attenuate acute lung injury (ALI) in rabbits induced with endotoxin.Methods Thirty-two healthy adult New Zealand rabbits were anaesthetized...
Summary: By using immunohistochemistry LSAB method and imaging analysis technique, the ex- pression of al-antitrypsinase (α1-AT) in 41 cases of bronchioalveolar carcinoma (BAC) was quan- titatively detected to explo...