Α1-ANTITRYPSIN

作品数:6被引量:26H指数:3
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相关领域:医药卫生更多>>
相关机构:无锡市妇幼保健院苏州大学更多>>
相关期刊:《Chinese Medical Journal》《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Journal of Hainan Medical University》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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α1-antitrypsin combined with bone marrow mesenchymal stem cells regulates retinopathy in diabetic rats via p38 MAPK/NF-κB signaling pathway
《Journal of Hainan Medical University》2021年第1期10-15,共6页Hong Chen Chu-Hua Li Wen-Jun Wang Rong Zeng Huan-Huan Yan Hong Zhang 
Key Rearch and Development projects in Shaanxi Province(2019SF-084).
Objective:To investigate the effect ofα1-antitrypsin combined with bone marrow mesenchymal stem cells on retinopathy in diabetic rats and its mechanism.Methods:A model of diabetic retinopathy was established by intra...
关键词:Α1-ANTITRYPSIN Bone marrow mesenchymal stem cells DIABETES RETINOPATHY Vascular endothelial growth factor p38 MAPK/NF-κB pathway 
Plasma αl-antitrypsin: A Neglected Predictor of Angiographic Severity in Patients with Stable Angina Pectoris被引量:4
《Chinese Medical Journal》2015年第6期755-761,共7页Hui Zhao Hong Liu Lin Chai Ping Xu Lu Hua Xiao-Yuan Guan Bing Duan Yi-Ling Huang Yi-Shi Li 
Background:As an acute phase protein,α1-antitrypsin (AAT) has been extensively studied in acute coronary syndrome,but it is unclear whether a relationship exists between AAT and stable angina pectoris (SAP).The purpo...
关键词:Α1-ANTITRYPSIN ANGIOGRAPHY Coronary Artery Disease Gensini Score Inflammation Stable ANGINA PECTORIS 
α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation被引量:2
《Cellular & Molecular Immunology》2014年第4期377-386,共10页Avishag Abecassis Ronen Schuster Galit Shahaf Eyal Ozeri Ross Green David E Ochayon Peleg Rider Eli C Lewis 
Although islet transplantation for individuals with type I diabetes has been shown to yield superior blood glucose control, it remains inadequate for long-term control. This is partly due to islet injuries and stresse...
关键词:adaptive immunity inflammation innate immunity MACROPHAGES TOLERANCE 
Inhibition of histamine release from human mast cells by natural chymase inhibitors被引量:9
《Acta Pharmacologica Sinica》2004年第6期822-826,共5页Shao-hengHE HuaXIE Xiao-junZHANG Xian-jieWANG 
Project supported by the National Natural Science Foundationof China; No 30140023;and the Li KaShing Foundation; HongKong; China. No C0200001
AIM: To investigate the ability of natural chymase inhibitors to modulate histamine release from human mast cells. METHODS: Enzymatically dispersed cells from human lung, tonsil, and skin were challenged with anti-Ig...
关键词:CHYMASE mast cells immunoglobulin E histamine release calcium ionophore secretory leukocyte  protease inhibitor Α1-ANTITRYPSIN ALLERGY 
Protective effects of α_1 -antitrypsin on acute lung injury in rabbits induced by endotoxin被引量:11
《Chinese Medical Journal》2003年第11期1678-1682,共5页揭志军 蔡映云 杨文兰 金美玲 朱威 祝慈芳 
the Scientific Foundation of the Ministry of Health (No: 98-1-150)
Objective To investigate whether pretreatment with α1,-antitrypsin (AAT) can attenuate acute lung injury (ALI) in rabbits induced with endotoxin.Methods Thirty-two healthy adult New Zealand rabbits were anaesthetized...
关键词:acute lung injury ·α1-antitrypsin neutrophil elastase ·rabbits ENDOTOXIN 
Relationship between the Expression of α1-Antitrypsinase in Bronchioalveolar Carcinoma and Clinical Pathology
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2000年第1期26-28,共3页吴翠环 陈春莲 杨毅 郝春荣 倪娟 车东媛 
Summary: By using immunohistochemistry LSAB method and imaging analysis technique, the ex- pression of al-antitrypsinase (α1-AT) in 41 cases of bronchioalveolar carcinoma (BAC) was quan- titatively detected to explo...
关键词:bronchioalveolar carcinoma α1-antitrypsinase IMMUNOHISTOCHEMISTRY imaging analysis 
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