PRODRUGS

作品数:67被引量:100H指数:5
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相关领域:医药卫生化学工程更多>>
相关作者:张礼和谢璐佳郭颖卢俊峰徐靖源更多>>
相关机构:中国医学科学院北京协和医学院北京大学香港城市大学天津医科大学更多>>
相关期刊:《Nano-Micro Letters》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金天津市自然科学基金中国博士后科学基金教育部留学回国人员科研启动基金更多>>
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Triphenylmethanol Conjugates of Triptorelin as Anti-Lipid Peroxidation Prodrugs
《Open Journal of Medicinal Chemistry》2019年第3期49-62,共14页Samiyah Alhamed Jawzah Alnakhli William Boadi Ryan Beni 
Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. Free radicals may play a role...
关键词:ANTIOXIDANTS PRODRUGS TRIPTORELIN POLYPHENOLS Lipid PEROXIDATION Triphenylmethanol 
Synthesis and Antiproliferative Activities of Triphenylmethanol Conjugates of Leuprorelin
《Open Journal of Medicinal Chemistry》2019年第2期37-47,共11页Ryan Beni William Boadi Kaleh Karim Jawzah Alnakhli Samiyah Alhamed 
Leuprorelin®(LEP) is an FDA drug for breast cancer and prostate cancer treatment. There are several reported adverse effects such as transient hypertension, excessive salivation, and increased dysuria during trea...
关键词:PRODRUGS LEUPRORELIN POLYPHENOLS PROSTATE Cancer Triphenylmethanol 
Synthesis and Evaluation of Glyceride Prodrugs of Naproxen被引量:2
《Open Journal of Medicinal Chemistry》2013年第3期87-92,共6页Vivekkumar K. Redasani Sanjay B. Bari 
The glyceride ester derivatives 6a and 6b were prepared by reacting 1,2,3-trihydroxy propane 1,3-dipalmitate/stearate with (S)-naproxen as potential prodrugs. The synthesis was achieved successfully with the aid of N,...
关键词:NAPROXEN GLYCERIDE PRODRUGS ANTI-INFLAMMATORY ANALGESIC GASTROPROTECTIVE Hydrolysis Kinetics 
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