NAPROXEN

作品数:47被引量:48H指数:3
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相关领域:医药卫生化学工程更多>>
相关作者:文敏刘欢潘钧铸戴天许振良更多>>
相关机构:四川大学上海第二工业大学华东理工大学天津医科大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》《Advances in Biological Chemistry》更多>>
相关基金:国家自然科学基金上海市教育委员会重点学科基金上海市教育委员会创新基金湖北省自然科学基金更多>>
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Synthesis and Characterization of Naproxen-Salicylate Derivatives as Potential Dual-Targeted Inhibitors of Dihydrofolate Reductase
《Advances in Biological Chemistry》2024年第4期87-102,共16页Syon Schlecht Emily Gunderson Ruthie Fowler Takara Aguilar 
Dihydrofolate reductase (DHFR) is an enzyme that catalyzes the reduction of dihydrofolate (DHF) to tetrahydrofolate (THF). Chemotherapy drugs such as methotrexate help to slow the progression of cancer by limiting the...
关键词:Dihydrofolate Reductase DHFR Chemotherapy Nonsteroidal Anti-Inflammatory Drugs NSAIDS Folate Metabolism Pathway Anti-Folate Novel Therapeutic Development 
Chemical inhibition of Arabidopsis PIN-FORMED auxin transporters by the anti-inflammatory drug naproxen被引量:2
《Plant Communications》2023年第6期234-243,共10页Jing Xia Mengjuan Kong Zhisen Yang Lianghanxiao Sun Yakun Peng Yanbo Mao Hong Wei Wei Ying Yongxiang Gao Jiri Friml Jianping Weng Xin Liu Linfeng Sun Shutang Tan 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB37020103 to Linfeng Sun);research funds from the Center for Advanced Interdisciplinary Science and Biomedicine of IHM,Division of Life Sciences and Medicine,University of Science and Technology of China(QYPY20220012 to S.T.);start-up funding from the University of Science and Technology of China and the Chinese Academy of Sciences(GG9100007007,KY9100000026,KY9100000051,KJ2070000079 to S.T.);the National Natural Science Foundation of China(31900885 to X.L.,31870732 to Linfeng Sun);the Natural Science Foundation of Anhui Province(2008085MC90 to X.L.,2008085J15 to Linfeng Sun);the Fundamental Research Funds for the Central Universities(WK9100000021 to S.T.,WK9100000031 to Linfeng Sun);and the USTC Research Funds of the Double First-Class Initiative(YD9100002016 to S.T.,YD9100002004 to Linfeng Sun).Linfeng Sun is supported by an Outstanding Young Scholar Award from the Qiu Shi Science and Technologies Foundation and a Young Scholar Award from the Cyrus Tang Foundation.
The phytohormone auxin plays central roles in many growth and developmental processes in plants.Development of chemical tools targeting the auxin pathway is useful for both plant biology and agriculture.Here we reveal...
关键词:auxin transport PIN NAPROXEN ARABIDOPSIS NPA 
Rectal nonsteroidal anti-inflammatory drugs,glyceryl trinitrate,or combinations for prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis:A network meta-analysis被引量:2
《World Journal of Clinical Cases》2022年第22期7859-7871,共13页Qing-Qing Shi Guo-Xiu Huang Wei Li Jian-Rong Yang Xiao-Yi Ning 
BACKGROUND Acute pancreatitis is the most common and severe complication of endoscopic retrograde cholangiopancreatography(ERCP).Recent evidence suggests that combinations based on rectal nonsteroidal anti-inflammator...
关键词:Endoscopic retrograde cholangiopancreatography PANCREATITIS DICLOFENAC INDOMETHACIN NAPROXEN Glyceryl trinitrate 
An acute naproxen dose does not affect core temperature or Interleukin-6 during cycling in a hot environment
《Sports Medicine and Health Science》2021年第4期243-251,共9页Dawn M.Emerson Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson J.Mark Davis 
Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during exercise.We utilized a doubl...
关键词:CYTOKINE Exertional heat illness NSAIDS THERMOREGULATION Exercise 
A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat
《Sports Medicine and Health Science》2020年第1期19-24,共6页Dawn M.Emerson J.Mark Davis Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson Joseph D.Bivona Justin V.Stone 
Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 trial...
关键词:NSAID Gastrointestinal bleeding Heart rate Perceived exertion 
Evaluation of naproxen-induced oxidative stress, hepatotoxicity and in-vivo genotoxicity in male Wistar rats被引量:1
《Journal of Pharmaceutical Analysis》2018年第6期400-406,共7页Mir Hilal Ahmad Mahino Fatima Mobarak Hossain Amal Chandra Mondal 
supported by grants from DBT NER (BT/ PR16164/NER/95/88/2015);DST PURSE-(Phase-Ⅱ)(PAC-JNU-DSTPURSE-462);UGC RNW,UGC SAP at the level of DRS-Ⅰ & Ⅱ,and UPE-Ⅱ,JNU(Project Id No. 247)
Naproxen(NP), a nonsteroidal anti-inflammatory drug(NSAID), is used for the treatment of common pain, inflammation and tissue damage. Genotoxicity testing of NP is of prime importance as it represents the largest grou...
关键词:GENOTOXICITY NAPROXEN WISTAR rat ANTIOXIDANTS Oxidative stress DNA damage 
Facile Preparation and Extensive Characterization of Naproxen–β-Cyclodextrin Inclusion Complex
《Journal of Analysis and Testing》2017年第2期94-99,共6页Guiying Jin Hui Chen 
the Guangdong Province Science and Technology Program Foundation(No.2013B040200029);2016 National Drug Evaluation Special Foundation of China and the National Natural Science Foundation of China(21375027,21335002,and 21427806).
Naproxen–β-cyclodextrin inclusion complex was prepared by the freeze-drying method and analyzed by IR,UV spectroscopy,X-ray diffractometry and differential scanning calorimetry.Phase solubility,dissolution and inclu...
关键词:Β-CYCLODEXTRIN NAPROXEN Inclusion rate Complex XRD DSC 
Suppository naproxen reduces incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis: Randomized controlled trial被引量:6
《World Journal of Gastroenterology》2016年第21期5114-5121,共8页Fariborz Mansour-Ghanaei Farahnaz Joukar Zahra Taherzadeh Homayoon Sokhanvar Tolou Hasandokht 
AIM: To determine the efficacy of rectally administered naproxen for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).METHODS: This double-blind randomized control trial ...
关键词:NAPROXEN Nonsteroidal anti-inflammatory drugs Pancreatic duct injection Post-endoscopic retrograde cholangiopancreatography PANCREATITIS Serum amylase 
Bio-Functional Nanodiamond Restorative Materials Containing Bio-Additives: In Vitro Approach
《Open Journal of Stomatology》2015年第5期117-126,共10页Victoria Tamara Perchyonok Tatiana Souza Rafael Felliti Shengmiao Zhang Sias Grobler 
Restorative materials in the new era aim to be “bio-active”, bio-functional and long-lasting. As a part of our continuous interest of developing functional dual action restorative materials capable of being “bio-ac...
关键词:Therapeutic Polymers Adhesives Chitosan Hydrogels PROPOLIS MELATONIN NAPROXEN Antimicrobial DENTIN Bonding Antioxidants Bioactive 
Synthesis and Biological Activity of Drug Delivery System Based on Chitosan Nanocapsules
《Advances in Nanoparticles》2014年第4期148-158,共11页Mohamed Gouda Usama Elayaan Magdy M. Youssef 
Chitosan nanocapsules containing naproxen as an active ingredient were synthesized by ionic gelation method in presence of polyanion tripolyphosphate as a crosslinker. The morphology and diameter of the prepared chito...
关键词:CHITOSAN NAPROXEN NANOCAPSULES DRUG Delivery Systems ANTIMICROBIAL ANTIOXIDANT DNA Degradation 
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