supported by Liaoning Revitalization Talents Program(No.XLYC1907173);the Science and Technology General Project of Liaoning Provincial Education Department(No.LJKMZ20221835);the National Natural Science Foundation of China(Nos.22006073 and 22205027).
The mass production and widespread use of Pharmaceuticals and Personal Care Products(PPCPs)have posed a serious threat to the water environment and public health.In this work,a green metal-based Metal Organic Framewor...
This study investigated whether liposomes could enhance the permeation and penetration of diclofenac diethylammonium. For this, a 1.16% diclofenac diethylammonium liposome gel formulation was developed (Grupo Leti, S....
Gene circuits allow cells to carry out complex functions such as the precise regulation of biological metabolic processes.In this study,we combined,in the yeast S.cerevisiae,genetic regulatory elements with the enzyma...
BACKGROUND: Pain management following caesarean section still remains a challenge in our environment. Most potent analgesics are either not readily available or expensive. Diclofenac suppository is an NSAID that can b...
Objectives: Evaluate the bioequivalence (BE) of two oral tablets formulations of diclofenac 150 mg in healthy male subjects under fasting condition. This was a phase I, randomized, open label, balanced, two period, tw...
Background Actinic keratosis is the most prevalent premalignant skin disorder in the white population. Current guidelines provide no clear recommendations about preferred treatments. Methods The parameters;effectivene...
Background: Osteoarthritis is a chronic disease associated with pain, inflammation, stiffness and synovial effusion, with progressive functional limitation, compromising quality of life. It progressively leads to loss...
We present the structural,morphological and photocatalytic properties of stretchable composites made with carbon nanotubes (CNTs),silicon rubber and Ni@TiO_(2):W nanoparticles(TiWNi NPs) with average size of 37±2 nm....
financially supported by the program for the National Natural Science Foundation of China (Nos. 51979044,42177045 and 42107053);the Guangdong Natural Science Funds for Distinguished Young Scholar (No. 2019B151502023);Guangdong International Training Program for Outstanding Young Talents;the China Postdoctoral Science Foundation (No. 2021M700878);Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health (No. 2020B1212030008)。
The large consumption and discharge of diclofenac(DCF) lead to its frequent detection in surface water and groundwater, posing great threats to humans and ecosystems. This study explored the oxidation kinetics of DCF ...
Objective:To investigate the potential synergistic activity of diclofenac with piperine and D-limonene in inducing apoptosis and cell cycle arrest in breast cancer MCF-7 cells.Methods:Molecular docking study was condu...