云南高校图书馆联盟文献共享服务平台- IMIQUIMOD

IMIQUIMOD: 作品数：47被引量：111H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：张艳丽任书荣王秋波吴静倪均更多>>; 相关机构：青岛大学吉林大学第一医院四川大学华西医院上海交通大学医学院附属第九人民医院更多>>; 相关期刊：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Asian Pacific Journal of Tropical Biomedicine》《Journal of Integrative Medicine》《Food Science and Human Wellness》更多>>; 相关基金：国家自然科学基金中国博士后科学基金山东省医药卫生科技发展计划项目山东省自然科学基金更多>>

Protective effects of Bifi dobacterium breve on imiquimod-induced psoriasis in mice through secondary bile acid production and FXR-TLR4/NF-κB pathway: 《Food Science and Human Wellness》2024年第6期3447-3460,共14页Xinqi Chen Yang Chen Catherine Stanton RPaul Ross Jianxin Zhao Bo Yang Wei Chen; supported by the National Natural Science Foundation of China(32072227,32021005);111 Project(BP0719028);the Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province.; This study aimed to evaluate the effects of Bifi dobacterium breve CCFM683 on psoriasis and to investigate the underlying mechanisms.B.breve CCFM683 significantly ameliorated psoriasis in mice as well as elevated the ...; 关键词：PSORIASIS Bifi dobacterium breve Gut microbiota Secondary bile acids FXR-TLR4/NF-κB pathway

Coleus forskohlii shows anti-psoriatic activity in imiquimod-induced psoriasis rats: 《Asian Pacific Journal of Tropical Biomedicine》2024年第9期382-390,I0002-I0007,共15页Sagarika Majhi Iti Chauhan Deepak Kumar Md.Niyaz Alam Md.Sarfaraj Hussain Muzaffar Iqbal; supported by Researchers Supporting Project number(RSPD2024R734);King Saud University,Riyadh,Saudi Arabia.; Objective:To evaluate anti-psoriatic activity of Coleus forskohlii in rats with imiquimod-induced psoriasis.Methods:Imiquimod was used to induce psoriasis in rats.Body weight,skin thickness,erythema,scaling,spleen wei...; 关键词：PSORIASIS Coleus forskohlii Emulgel Ex vivo IMIQUIMOD CARBOPOL

Imiquimod:A potential option for inhibition of repigmentation of congenital melanocytic nevus after laser ablation: 《Chinese Journal of Plastic and Reconstructive Surgery》2024年第2期76-78,共3页Yifei Zhao Yun Zou Xiangyu Chen Hanlin Zeng Hanru Ying Xiaoxi Lin Hui Chen; supported by Shanghai Municipal Key Clinical Specialty (grant no. shslczdzk00901);Clinical Research Project of Multi-Disciplinary Team, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine; Congenital melanocytic nevi(CMN) are common skin tumors. Large and specially located nevi cannot be completely removed by surgery, posing the risks of both cosmetic deformities and potential malignancy.Nonsurgical tre...; 关键词：IMIQUIMOD Congenital melanocytic nevus RECURRENCE Laser

Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy被引量：1: 《Bioactive Materials》2024年第4期466-481,共16页Peishan Li Ying Xie Jinling Wang Chunjie Bao Jialun Duan Yixuan Liu Qian Luo Jiarui Xu Yuxin Ren Min Jiang Jianwei Li Haitao Guo Huihui Zhao Guiling Wang Yanqin Liang Wanliang Lu; supported by the National Natural Science Foundation of China(No.82173752 and No.81874303).; Cancer patients by immune checkpoint therapy have achieved long-term remission,with no recurrence of clinical symptoms of cancer for many years.Nevertheless,more than half of cancer patients are not responsive to this...; 关键词：Gene engineered exosomes T cell exhaustion PD1/PDL1 IMIQUIMOD Cancer immunotherapy

Rutaecarpine ameliorates imiquimod-induced psoriasis-like dermatitis in mice associated with alterations in the gut microbiota: 《Acta Biochimica et Biophysica Sinica》2024年第3期345-355,共11页Yongjian Li Zhengping Tan Wencan Li Zongxuan Li Guiying Zhang; This work was supported by the grant from the Natural Science Foundation of Changsha(No.kq2202410).; Psoriasis is accepted as a chronic,inflammatory,immune-mediated skin disease triggered by complex environmental and genetic factors.For a long time,disease recurrence,drug rejection,and high treatment costs have remai...; 关键词：PSORIASIS rutaecarpine(RUT) inflammatory factor gut microbiota

Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB被引量：3: 《Food Science and Human Wellness》2024年第1期211-224,共14页Xianshe Meng Shihong Zheng Zequn Yin Xuerui Wang Daigang Yang Tingfeng Zou Huaxin Li Yuanli Chen Chenzhong Liao Zhouling Xie Xiaodong Fan Jihong Han Yajun Duan Xiaoxiao Yang; supported by the National Natural Science Foundation of China(NSFC)(81973316,82173807);the China Postdoctoral Science Foundation(2020M681914);the Fund from Tianjin Municipal Health Commission(ZC200093);the Open Fund of Tianjin Central Hospital of Obstetrics and Gynecology/Tianjin Key Laboratory of human development and reproductive regulation(2021XHY01)。; Psoriasis is a chronic autoimmune disease featured by patches on the skin.It is caused by malfunction of immune cells and keratinocytes with inflammation as one of its key features.Apigenin(API)is a natural flavonoid ...; 关键词：PSORIASIS APIGENIN IMIQUIMOD Inflammation Signal transducer activator of transcription 3 (STAT3) Nuclear factor-κB(NF-κB)

Holistic Approach in the Treatment of Actinic Keratosis: Benefits and Disadvantages of 5-Fluorouracil, Imiquimod, Diclofenac and Curaderm: 《International Journal of Clinical Medicine》2023年第7期319-331,共13页Bill Elliot Cham; Background Actinic keratosis is the most prevalent premalignant skin disorder in the white population. Current guidelines provide no clear recommendations about preferred treatments. Methods The parameters;effectivene...; 关键词：Actinic Keratosis Skin Cancer 5-FLUOROURACIL IMIQUIMOD DICLOFENAC Curaderm EFFICACY RECURRENCE Cost

Preparation and In vitro Evaluation of Polydopamine-coated Immunoadjuvant Nanoparticles: 《Medicinal Plant》2023年第2期38-42,62,共6页Meng LI Haiyu TANG Lili HE Lu HAN; Supported by National Natural Science Foundation of China(82003683);Fundamental Research Funds for the Central Universities of Southwest Minzu University(2021105)。; [Objectives]The paper was to prepare immunoadjuvant nanoparticles with good photothermal conversion efficiency and to achieve the synergistic antitumor effect of phototherapy and immunotherapy.[Methods]Poly(lactic-co-...; 关键词：POLYDOPAMINE IMIQUIMOD NANOPARTICLES TUMOR Photothermal therapy IMMUNOTHERAPY

Liangxue Xiaoban decoction and its disassembled prescriptions ameliorate psoriasis-like skin lesions induced by imiquimod in mice via T cell regulation: 《Journal of Traditional Chinese Medical Sciences》2022年第4期409-419,共11页Feifei Tang Shuling Liu Fafeng Cheng Qingguo Wang Xueqian Wang; This experimental study was supported by the Key Research Project of the Beijing University of Chinese Medicine(2020-JYBZDGG-023);Young Qihuang Scholars Project(90020163320001).; Objective:To explore the therapeutic capacity of the Liangxue Xiaoban(LXXB)decoction and its disassembled prescriptions in the modulation of T cell subsets and recurrence-related indexes of psoriasis using a psoriasis...; 关键词：PSORIASIS T cells Recurrence Liangxue Xiaoban decoction Disassembled prescription Tripterygium glycoside

Spatio-temporal delivery of both intra-and extracellular toll-like receptor agonists for enhancing antigen-specific immune responses被引量：1: 《Acta Pharmaceutica Sinica B》2022年第12期4486-4500,共15页Nannan Wang Yueyue Zuo Shengjie Wu Chenlu Huang Linhua Zhang Dunwan Zhu; This work was financially supported by National Natural Science Foundation of China(82072059 and 82172090);CAMS Innovation Fund for Medical Sciences(CIFMS,2021-I2M-1-058,China);Fundamental Research Funds for the Central Universities(2019PT320028 and 2019-0831-03,China);Tianjin Municipal Natural Science Foundation(20JCYBJC00030,China).; For cancer immunotherapy,triggering toll-like receptors(TLRs)in dendritic cells(DCs)can potentiate antigen-based immune responses.Nevertheless,to generate robust and long-lived immune responses,a well-designed nanovac...; 关键词：Lipid-polymer hybrid nanoparticles TLR agonist combinations OVALBUMIN Monophosphoryl lipid AImiquimod NANOVACCINE Spatio-temporal manner Cancer immunotherapy

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