This work was financially supported by the National Natural Science Foundation of China(grant number:8217150152);the Clinical Science and Technology Innovation Project of Shanghai Shenkang Hospital Development Center(grant number:SHDC12021102);the Shanghai Three-Year Action Plan to Further Accelerate the Development of Traditional Chinese Medicine Inheritance and Innovation(grant number:ZY(2021-2023)-0209-05).
Background:Adenoid hypertrophy(AH)is a common pediatric disease that signifi-cantly impacts the growth and quality of life of children.However,there is no replica-ble and valid model for AH.Methods:An AH rat model was...
sopported by National Natural Science Foundation of China(31960457);Jiangxi Province National Science and Technology Prizes Backup Project and Cultivation Plan(20212AEI91001).
Gut microbiota plays an important role in food allergy.The immunoglobulin G(IgG)/immunoglobulin E(IgE)binding capacity and human gut microbiota changes of digestion products derived from glycated ovalbumin(OVA)were in...
Science and Technology Development Plan Project of Jilin Provincial:Research on the Development of Baijin Pingchuan Granules as an In-hospital Preparation for the Treatment of Pediatric Asthma (Heat-type Asthma)(No. 20200404043YY);Traditional Chinese Medicine Science and Technology Project of Jilin Provincial:Exploring the Mechanism of Baijin Pingchuan Granules in Alleviating Airway Inflammation in Asthma based on the “Three-Stage Differentiation and Treatment” Theory of National Medical Masters (2020090)。
OBJECTIVE: To investigate the effect of baijinpingchuan(白金平喘, BJPC) on the asthma rat model and identify differential metabolites and disturbed metabolic pathways. METHODS: The rats were categorized into six group...
supported by the Guangdong Basic and Applied Basic Research Foundation(2021B1515130004;2021B1515140021);the Scientific Research Start-up Funding of Guangdong Medical University(1026/4SG21229G);China Postdoctoral Science Foundation(2021M702781);Guangdong Medical University Post-doctoral Research Funding(2BH19006P)。
Ovalbumin(OVA)is the major allergenic protein that can induce T helper 2(Th2)-allergic reactions,for which current treatment options are inadequate.In this study,we developed a polymerized hypoallergenic OVA product v...
Objective:To evaluate the anti-allergic effect of boeravinone B against ovalbumin-induced allergic rhinitis in mice and explore its possible mechanism.Methods:For the induction of allergic rhinitis,mice were intraperi...
financially supported by the National Key R&D Program of China (2019YFC1605003);the Zhejiang Provincial Natural Science Foundation of China (LGN21C200013)。
Bacillus coagulans has been extensively studied so far,but there has been a lack of research on its usage in allergy.In this study,we designed to assess the effect of different concentrations of B.coagulans on food al...
the Innovation-Driven Development Capacity Enhancement Fund of Shanxi Province(SXYBKY2019041);National Key Research and Development Program(2021YFD1600604-03);Shanxi Scholarship Council of China(2021-068);Shanxi Agricultural University High-Level Talent Project(2021XG013).
This study aimed to investigate the effects of phosphorylated-ovalbumin(P-OVA)at different concentrations(0.5%and 1.0%)on the gel properties of pork myofibrillar protein(MP).The results showed that the textural proper...
the financial support of the National Natural Science Foundation of China(32171352);Special Funds for Provincial Science and Technology Programs(Key R&D Program for Social Development)of Jiangsu Province(BE2023743);Open Research Fund of State Key Laboratory of Advance Technology for Materials Synthesis and Processing(Wuhan University of Technology,2023-KF-18);Open Research Fund of State Key Laboratory of Bioelectronics,Southeast University(2023-K05);Opening Project of State Key Laboratory of Polymer Materials Engineering(Sichuan University,Sklpme2022-4-01);226 High-level Talent Training Project(2nd level,2022 II-276).
Peripheral nerve injury(PNI)seriously affects the health and life of patients,and is an urgent clinical problem that needs to be resolved.Nerve implants prepared from various biomaterials have played a positive role i...
Objective:To evaluate the effect of rosmarinic acid on tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats.Methods:Rats were randomly divided into six groups:the control gr...
supported by grants from the National Natural Science Foundation of China(Nos.81760009 and 81560007).
Introduction:Allergen-specific CD4+T cells play a central role in autoimmune disorders,allergies and asthma,with Th2-type immunity being the typical functional response of CD4+T cells.This study aimed to investigate t...