PIPERINE

作品数：27被引量：81H指数：5
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相关领域：医药卫生更多>>
相关作者：赵佳佳周毅王婷蒋学华王凌更多>>
相关机构：教育部武汉大学附属口腔医院重庆医科大学附属第一医院四川大学更多>>
相关期刊：《International Journal of Ophthalmology(English edition)》《Neural Regeneration Research》《中国药理学通报》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金更多>>
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Piperine regulates the circadian rhythms of hepatic clock gene expressions and gut microbiota in high-fat diet-induced obese rats
《Food Science and Human Wellness》2024年第3期1617-1627,共11页Weiyun Zhang Chi-Tang Ho Wenlian Wei Jie Xiao Muwen Lu 
financially supported by the Program for Guangdong Introducing Innovative and Entrepreneurial Teams (2019ZT08N291);the National Natural Science Foundation of China (31901689);the Natural Science Foundation of Guangdong Province,China (2021A1515012124)。
The interplay between the host circadian clock and microbiota has significant influences on host metabolism processes,and circadian desynchrony triggered by high-fat diet(HFD)is closely related to metabolic disorders....
关键词：PIPERINE Circadian clock OBESITY Gut microbiota 
Green tea extract and Piper retrofractum attenuate deoxycholic acid-induced damage and enhance the tight junction barrier: An analysis in a Caco-2 cell culture model and a DSS coinduced mouse model
《Food Bioscience》2023年第2期541-548,共8页Kwanyong Choi Soo-yeon Park Yuri Kwon Jinhee Lee Oran Kwon Ji Yeon Kim 
This work was supported by the Bio-Synergy Research Project(NRF2013M3A9C4078159)of the Ministry of Science,ICT and Future Planning through the National Research Foundation.
This study investigated the effect of green tea extract(GTE)and green tea-Piper retrofractum complex(GPX),on tight junctions(TJs)in a cellular model of deoxycholic acid(DCA)-induced intestinal barrier disruption and a...
关键词：Green tea and Piper retrofractum CATECHIN PIPERINE Deoxycholic acid Tight junction barrier 
Combinatorial effect of diclofenac with piperine and D-limonene on inducing apoptosis and cell cycle arrest of breast cancer cells
《Asian Pacific Journal of Tropical Biomedicine》2023年第2期80-92,共13页Srivarshini Sankar Gothandam Kodiveri Muthukaliannan 
Objective:To investigate the potential synergistic activity of diclofenac with piperine and D-limonene in inducing apoptosis and cell cycle arrest in breast cancer MCF-7 cells.Methods:Molecular docking study was condu...
关键词：Breast cancer Diclofenac sodium PIPERINE D-LIMONENE Reactive oxygen species Cell cycle arrest APOPTOSIS 
Pharmacotherapeutics and molecular docking studies of alphasynuclein modulators as promising therapeutics for Parkinson’s disease被引量：2
《BIOCELL》2022年第12期2681-2694,共14页RAHAT ALI AFTAB ALAM SATYENDRA K.RAJPUT RAZI AHMAD 
Parkinson’s disease(PD)is an age-related neurodegenerative ailment that affects dopamine-producing neurons in a specific area of the brain called the substantia nigra of the ventral midbrain.It is clinically characte...
关键词：Parkinson’s disease(PD) ALPHA-SYNUCLEIN Molecular docking and dynamics Anti-Parkinson drug Curcumin PIPERINE 
Piperine attenuates production of inflammatory biomarkers,oxidative stress and neutrophils in lungs of cigarette smoke-exposed experimental mice
《Food Bioscience》2022年第5期1285-1298,共14页Poonam Arora Seyyed Shamsadin Athari Lalit Mohan Nainwal 
Notice for SRF,45/48/2011/BMS/TRM,dated 28-05-2013.Indian Council of Medical Research(ICMR),India.
Cigarette smoking(CS)induced chronic obstructive pulmonary disease(COPD)is third leading cause of global pulmonary health issue.Currently,there is no effective therapeutic strategy to control perpetuating inflammatory...
关键词：PIPERINE Cigarettes smoke Chronic obstructive pulmonary disease(COPD) Oxidative stress Pro-inflammatory mediators 
Piperine suppresses growth and migration of human breast cancer cells through attenuation of Rac1 expression被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2022年第1期39-46,共8页Benjaporn Buranrat Mutita Junking 
financially supported by Mahasarakham University 2021(MSU2021).
Objective:To investigate the effect of piperine on human breast cancer cells.Methods:The effect of piperine on proliferation and migration of human breast cancer cells,MCF-7 and MDA-MB-231,was investigated using colon...
关键词：PIPERINE Breast cancer cells RAC1 Cell cycle Cell migration MCF-7 MDA-MB-231 
Piperine treating sciatica through regulating inflammation and MiR-520a/P65 pathway被引量：5
《Chinese Journal of Natural Medicines》2021年第6期412-421,共10页YU Jiu-Wang LI Sha BAO Li-Dao WANG Lu 
supported by the National Natural Science Foundation of China(Nos.81760748,81550047);the Natural Science Foundation of Inner Mongolia Autonomous Region(Nos.2018LH08032,2017MS0831);Inner Mongolia Autonomous Region"Prairie Excellence"Project,West Light Foundation of the Chinese Academy of Sciences,the Major Science Foundation of Affiliated Hospital of Inner Mongolia Medical University(No.NY-FY ZD010).
Although the etiology of sciatica remains uncertain,there is increasing evidence that the disease process of sciatica is associated with the levels of inflammatory factors.Piperine,an alkaloid isolated from Piper nigr...
关键词：PIPERINE SCIATICA miR-520a P65 Inflammatory factor 
To explore the potential vitiligo treatment mechanism of Piperine in Piperis Longi Fructus via network pharmacology and bioinformatics strategies
《TMR Integrative Medicine》2021年第10期1-10,共10页Ji-Hong Li Jia-Yu Zhang Yuan-Xia Zou 
Objective:To explore the mechanism of Piperine of Piperis Longi Fructus in the treatment of vitiligo based on network pharmacology and transcriptome.Methods:Piperine,the active component of Piperis Longi Fructus,was s...
关键词：PIPERINE VITILIGO Network pharmacology TRANSCRIPTOME Action mechanism 
Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression被引量：4
《International Journal of Ophthalmology(English edition)》2021年第5期656-665,共10页Pu Zhang Yan-Dan Zhou Yao Tan Ling Gao 
Supported by the National Natural Science Foundation of China(No.81072221);Projects of Research and Development in Key Areas of Hunan Province(No.2017SK2020;No.2020SK2133);the Natural Science Foundation of Hunan Province(No.2020JJ5005)。
AIM:To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes.METHODS:In experiments in vitro,stimulation by chemical hypoxia was established in ARPE-19 cells.Then,th...
关键词：diabetes diabetic retinopathy hypoxiainducible factor-1α/vascular endothelial growth factor A pathway pigment epithelium-derived factor PIPERINE MICE 
Natural compounds as potential inhibitors of SARS-CoV-2 main protease: An insilico study
《Asian Pacific Journal of Tropical Biomedicine》2021年第4期155-163,共9页Amaresh Mishra Yamini Pathak Anuj Kumar Surabhi Kirti Mishra Vishwas Tripathi 
Objective:To explore natural compounds as potential inhibitors against main protease(Mpro)of SARS-CoV-2.Methods:In the current study,systematic molecular docking analysis was conducted using AutoDock 4.2 to determine ...
关键词：SARS-CoV-2 COVID-19 AMENTOFLAVONE GUGGULSTERONE PUERARIN PIPERINE 
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