supported by the National Natural Science Foundation of China(Nos.81971943,81772196,31470264,81271820,30870789,and 30300117);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),United States(No.06R-1366);We acknowledge the Medicine Research Center for Structural Biology of Wuhan University for providing the confocal microscopy(Leica-LCS-SP8-STED).
The human endogenous retroviruses type W family envelope(HERV-W env)gene is located on chromosome 7q21-22.Our previous studies show that HERV-W env is elevated in schizophrenia and HERV-W env can increase cal-cium inf...
In multiple sclerosis(MS),human endogenous retrovirus W family(HERV-W)envelope protein,pHERV-W ENV,limits remyelination and induces microglia-mediated neurodegeneration.To better understand its role,we examined the so...
supported by grants from the National Natural Sciences Foundation of China(no.31470264,no.81271820,no.30870789 and no.30300117);the Key Program of the Natural Science Foundation of Hubei Province of China(no.2014CFA078);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),USA(no.06R-1366),for Dr.F Zhu;the Scientific Innovation Team Project of Hubei Province of China(no.2015CFA009)
Human endogenous retrovirus W family(HERV-W) envelope(env) has been reported to be related to several human diseases, including autoimmune disorders, and it could activate innate immunity.However, there are no reports...
目的明确PERV的整合是否影响HEK293细胞中HERV-W各基因表达水平。方法根据GenBank中登录的基因序列,分别设计HERV-W gag、HERV-W pol、HERV-Wenv、syncytin-1和humanβ-actin引物,并分别建立SYBR Green Ⅰ荧光定量PCR检测方法,用于检测H...
supported by grants from the National Natural Sciences Foundation of China(No.31470264,No.81271820,No.30870789,and No.30300117);the Key Program of Natural Science Foundation of Hubei Province of China(No.2014CFA078);the Stanley Foundation from the Stanley Medical Research Institute(SMRI),USA(No.06R-1366),to Dr.Fan Zhu;the Scientific Innovation Team Project of Hubei Province of China(No.2015CFA009)
Human endogenous retrovirus W env(HERV-W env) plays a critical role in many neuropsychological diseases such as schizophrenia and multiple sclerosis(MS). These diseases are accompanied by immunological reactions in th...