HEXAMER

作品数:13被引量:5H指数:1
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相关领域:生物学更多>>
相关期刊:《Science China(Life Sciences)》《Science China Chemistry》《Virologica Sinica》《Chinese Physics Letters》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2被引量:1
《Science China(Life Sciences)》2024年第6期1305-1307,共3页Songlin Gan Wen-Si Yang Liting Wei Zhiguo Zhang Rui-Ming Xu 
supported by the National Key Research and Development Program of China(2019YFA0508900);the National Natural Science Foundation of China(32330021,31991162,32200477);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB37010100)。
Dear Editor,The passage of DNA replication forks during eukaryotic cell division disrupts the nucleosomes they encounter,and de novo assembly of nucleosomes onto replicated DNA must take place to restore chromatin str...
关键词:STRUCTURE NUCLEOSOME passage 
PRPS2 mutations drive acute lymphoblastic leukemia relapse through influencing PRPS1/2 hexamer stability被引量:1
《Blood Science》2023年第1期39-50,共12页Lili Song Peifeng Li Huiying Sun Lixia Ding Jing Wang Benshang Li Bin-Bing S.Zhou Haizhong Feng Yanxin Li 
National Natural Science Foundation of China(81972341,81900158,81772663,81874078,82072896);Shanghai Municipal Science and Technology Commission(201409002700,19JC1413500,21XD1403100);Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(20161310);Pudong New Area Science&Technology Development Fund(PKJ2018-Y47).
Tumor relapse is the major cause of treatment failure in childhood acute lymphoblastic leukemia(ALL),yet the underlying mechanisms are still elusive.Here,we demonstrate that phosphoribosyl pyrophosphate synthetase 2(P...
关键词:Drug resistance Childhood acute lymphoblastic leukemia PRPS2 Purine metabolism Tumor relapse 
Cryo-EM Data Statistics and Theoretical Analysis of KaiC Hexamer
《Chinese Physics Letters》2022年第7期24-29,共6页Xu Han Zhaolong Wu Tian Yang Qi Ouyang 
supported by the National Natural Science Foundation of China (Grant No. 12090054)。
Cryo-electron microscopy(cryo-EM) provides a powerful tool to resolve the structure of biological macromolecules in natural state. One advantage of cryo-EM technology is that different conformation states of a protein...
关键词:Cryo-EM Data Statistics and Theoretical Analysis of KaiC Hexamer 
Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics被引量:1
《Virologica Sinica》2021年第5期1006-1026,共21页Benjamin Charvet Justine Pierquin Joanna Brunel Rianne Gorter Christophe Que´tard Branka Horvat Sandra Amor Jacques Portoukalian Herve´Perron 
supported by GeNeuro SA.
In multiple sclerosis(MS),human endogenous retrovirus W family(HERV-W)envelope protein,pHERV-W ENV,limits remyelination and induces microglia-mediated neurodegeneration.To better understand its role,we examined the so...
关键词:Multiple sclerosis(MS) Brain Antigen HERV-W ENVELOPE Endogenous retrovirus MSRV-ENV SYNCYTIN Demyelination Lipids GLYCOLIPIDS Sulfatides Oligomer HEXAMER 
Selective adsorption behaviors of guest molecules COR in the hexamer host networks at liquid/solid interface
《Chinese Chemical Letters》2021年第3期1077-1080,共4页Xiaokang Li Jianqiao Li Chunyu Ma Chen Chen Siqi Zhang Bin Tu Wubiao Duan Qingdao Zeng 
supported by the National Basic Research Program of China(No.2016YFA0200700);the National Natural Science Foundation of China(Nos.21773041 and 21972031);the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000)。
Here,the selective adsorption behaviors of guest molecule COR in two hexamer host grids were investigated by means of scanning tunnelling microscope(STM).The assembled structures of small functional organic molecules ...
关键词:Scanning probemicroscopy(STM) Selective adsorption Host-guest chemistry Supramolecular chemistry Aromatic carboxylic acid 
Self-assembly of L-tryptophan on Cu(111) studied by low-temperature scanning tunneling microscopy
《Chinese Chemical Letters》2019年第12期2355-2358,共4页Qiang Xue Yajie Zhang Ruoning Li Chao Li Na Li Chenyang Yuan Shimin Hou Yongfeng Wang 
supported by the Ministry of Science and Technology (Nos.2018YFA0306003,2017YFA0205003);National Natural Science Foundation of China (No.21972002);supported by High-performance Computing Platform of Peking University
The self-assembly of L-tryptophan on Cu(111) is investigated by an ultrahigh vacuum scanning tunneling microscope(STM) at 4.4 K.When deposited onto the substrate at around 120 K with a coverage of 0.1 monolayer,molecu...
关键词:Scanning tunneling microscopy TRYPTOPHAN SELF-ASSEMBLY Surface science HEXAMER 
Structure and Magnetic Properties of a Bipyridine-bridged One-dimensional Ni(Ⅱ) Coordination Polymer被引量:1
《Chinese Journal of Structural Chemistry》2014年第5期735-740,共6页张富青 周晶晶 黄齐茂 周红 潘志权 
the financial support from the National Natural Science Foundation of China(21171135);Hubei Provincial Science & Technology Department(2011BFA020);Hubei Independent Innovation Base(HBIR07)
A polymer, [NiL(bipy)·2H2O]n(1, bipy = 4,4ˊ-bipyridine), has been acquired by the reaction of Ni(OAc)2·4H2O with N,Nˊ-bis(2-hydroxyl-5-fluorobenzyl)-2-hydrxylpropane dii- mine in the presence of 4,4ˊ-bipy...
关键词:bipyridine-bridged coordination polymer Ni(Ⅱ) complex magnetic properties water hexamer 
Purification of enzymatically inactive peptidylarginine deiminase type 6 from mouse ovary that reveals hexameric structure different from other dimeric isoforms
《Advances in Bioscience and Biotechnology》2011年第4期304-310,共7页Hirofumi Taki Tomoharu Gomi Bryan Knuckley Paul R. Thompson Oliver Vugrek Kazuya Hirata Tatsurou Miyahara Kouichiro Shinoda Hiroyuki Hounoki Eiji Sugiyama Isao Usui Masaharu Urakaze Kazuyuki Tobe Tetsuya Ishimoto Ran Inoue Ayumi Tanaka Hiroki Mano Hirofumi Ogawa Hisashi Mori 
The murine peptidylarginine deiminase (PAD) has five isoforms encoded by different genes and participates in a variety of cellular functions through the citrullination of target proteins. The crystal structure of huma...
关键词:Peptidylarginine deiminase ISOFORM Dimer HEXAMER Mouse OOCYTES CYTOPLASMIC sheets. 
Liquid Water Structure from Anomalous Density under Ambient Condition
《Chinese Physics Letters》2006年第11期3022-3024,共3页孙樯 郑海飞 
Supported by the National Natural Science Foundation of China under Grant No 10032040, and the CNPC Innovation Fund.
From discussion of the structure of liquid water, we deduce that water under ambient condition is mainly composed of ice Ih-like molecular dusters and clathrate-like molecular clusters. The water molecular dusters rem...
关键词:LOW-ENERGY STRUCTURES AB-INITIO HEXAMER CLUSTERS TEMPERATURE SPECTROSCOPY PRESSURE SPECTRA CAGE 
Crystal structural studies of destripeptide (B28-B30) insulin
《Science China Chemistry》2000年第2期178-186,共9页叶军 茅毓新 桂璐璐 常文瑞 梁栋材 
Single crystals of destripeptide (B28-B30) insulin (DTRI) in three forms were obtained by hanging-drop vapor diffusion method. Form 1 belongs to P21 space group with cell parameters a-4.77 nm, b=6.19 nm, c=6.12 nm, β...
关键词:destripeptide INSULIN CRYSTAL STRUCTURE HEXAMER RECEPTOR-BINDING potency. 
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