Many experimental cancer vaccines are exploring toll-like receptor agonists (TLRas) such as CpG, a DNA motif that agonizes toll-like receptor 9 (TLR9), to trigger immune responses that are potent and molecularly-s...
This work was financially supported by the National Science and Technology Major Project (No. 2017YFA0205400), the Changjiang Scholar program, the National Natural Science Foundation of China (Nos. 81373983 and 81573377), China Postdoctoral Science Foundation (No. 2016M601923), and Postgraduate Research & Practice Innovation Program of Jiangsu Province (No. KYCX17_0671).
We report the development of a small interfering RNA (siRNA) delivery vector based on cationic perfluorocarbon nanoemulsions. We have prepared perfluorodecalin (PFD) emulsions with a positive surface charge provid...