云南高校图书馆联盟文献共享服务平台- POLYPLEX

POLYPLEX: 作品数：16被引量：9H指数：2; 导出分析报告; 相关领域：医药卫生化学工程更多>>; 相关作者：陈顺冯佳张士荣白光吴飞更多>>; 相关机构：上海交通大学沈阳药科大学更多>>; 相关期刊：《Chinese Journal of Polymer Science》《聚酯工业》《Neural Regeneration Research》《Asian Journal of Pharmaceutical Sciences》更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家教育部博士点基金更多>>

Tuning the Stability of the Polyplex Nanovesicles of Oligonucleotides via a Zinc(Ⅱ)-Coordinative Strategy: 《Chinese Journal of Polymer Science》2022年第9期1034-1042,共9页Quan Zhou Xiang Li Jia-Jia Xiang You-Qing Shen; financially supported by the National Key Research and Development Program of China (No.2021YFA1201200);the National Natural Science Foundation of China (Nos. 51833008, 52173141 and 82102192);Zhejiang Provincial Key Research and Development Program (No.2020C01123);China Postdoctoral Science Foundation (No.2019M662059); Oligonucleotide therapeutics have great potential to target the currently undruggable genes and to generate entirely new therapeutic paradigms in multiple types of disease,thus having attracted much attention in recen...; 关键词：Oligonucleotide therapeutics Polyplex nanovesicles Coordinative cationic block Lysosome-targeting

Hierarchical metal-phenolic-polyplex assembly toward superwetting membrane for high-flux and antifouling oil-water separation: 《Chinese Chemical Letters》2022年第8期3859-3864,共6页Xueting Zhao Yuanyuan Jiang Lijuan Cheng Youyou Lan Tingyuan Wang Jiefeng Pan Lifen Liu; financially supported by National Natural Science Foundation of China(No.21706230);China Postdoctoral Science Foundation(No.2019M652141);National Natural Science Foundation of China(Nos.22075246 and 21776253);Public Welfare Project of the Science and Technology Committee of Zhejiang Province(No.LGF20B060002);Provincial Key R&D Program of Zhejiang Province(No.2019C03094)。; Superwetting membranes have emerged as promising materials for the efficient treatment of oily wastewater.Typically,superwetting membranes can be developed by ingeniously chemical modification and topographical struct...; 关键词：Metal-phenolic POLYPLEX Superwetting MEMBRANE Oil-water separation

Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex nanoparticles reverses 6-hydroxydopamine-induced nigrostriatal neurodegeneration被引量：1: 《Neural Regeneration Research》2022年第4期854-866,共13页Manuel A.Fernandez-Parrilla David Reyes-Corona Yazmin M.Flores-Martinez Rasajna Nadella Michael J.Bannon Lourdes Escobedo Minerva Maldonado-Berny Jaime Santoyo-Salazar Luis O.Soto-Rojas Claudia Luna-Herrera Jose Ayala-Davila Juan A.Gonzalez-Barrios Gonzalo Flores Maria E.Gutierrez-Castillo Armando JEspadas-Alvarez Irma A.Martínez-Dávila Porfirio Nava Daniel Martinez-Fong; supported by the Consejo Nacional de Ciencia Tecnología(Conacyt)de México(Grant#254686,to DMF)。; Overexpression of neurotrophic factors in nigral dopamine neurons is a promising approach to reverse neurodegeneration of the nigrostriatal dopamine system,a hallmark in Parkinson's disease.The human cerebral dopamine...; 关键词：axonal growth brain-derived neurotrophic factor gene delivery NANOPARTICLES NEURITOGENESIS neuronal cytoskeleton neuroregeneration neurorestoration neurotrophic therapy Parkinson's disease REINNERVATION substantia nigra

Circumvent PEGylation dilemma by implementing matrix metalloproteinase-responsive chemistry for promoted tumor gene therapy被引量：1: 《Chinese Chemical Letters》2020年第12期3143-3148,共6页Jingyun Wang Hao Wang Hongyan Cui Peng Sun Xi Yang Qixian Chen; the National Natural Science Foundation of China(No.21878041);the funding support from Talent Project of Revitalizing Liaoning(No.XLYC1807184);Dalian Science&Technology Innovation Fund(Nos.2020JJ26SN050,2020JJ26GX025)。; Surface modification by poly(ethylene glycol)(PEGylation)has been acknowledged as a powerful strategy in minimizing non-specific reactions for biomedical devices.Once applied into manufacture of drug/gene delivery sys...; 关键词：PEGYLATION Tumor Polyplex micelle Gene delivery system Matrix metalloproteinase

Assembling structurally customizable synthetic carriers of si RNA through thermodynamically self-regulated process: 《Asian Journal of Pharmaceutical Sciences》2020年第3期356-364,共9页Guang Bai Tong Xue Xiaotao Dong Uday Kumar Chinta Jia Feng Tuo Jin Fei Wu; the grant of the Natural Science Foundation of China(Grant nos.81373352 and 81690262)。; This study demonstrates that our previously reported polywraplex, a synthetic siRNA carrier consisting of a uni-molecular polyplex core of customizable size and a self-assembled triblock copolymer envelop, may be cons...; 关键词：Networked cationic polymer Thermodynamically self-regulated processes siRNA delivery Unimolecular polyplex Zeta potential regulated polymerization

Polyplex interaction strength as a driver of potency during cancer immunotherapy被引量：2: 《Nano Research》2018年第10期5642-5656,共15页Shannon d. Tsai James I. Andorko Xiangbin Zeng Joshua M. Gammon Christopher M. dewell; Many experimental cancer vaccines are exploring toll-like receptor agonists （TLRas） such as CpG, a DNA motif that agonizes toll-like receptor 9 （TLR9）, to trigger immune responses that are potent and molecularly-s...; 关键词：cancer IMMUNOTHERAPY NANOPARTICLE VACCINE POLYPLEX

Enhancement of the transfection efficiency of DNA into Crocus sativus L. cells via PEI nanoparticles: 《Journal of Integrative Agriculture》2018年第8期1768-1778,共11页Behnam Firoozi Nasser Zare Omid Sofalian Parisa Sheikhzade-Mosadegh; supported by the University of Mohaghegh Ardabili, India under Grant (51-487); Over the past decade, several natural and synthetic cationic polymers have been utilized for gene delivery into cells. Among them, polyethylenimine(PEI) was used for gene therapy successfully. The present study invest...; 关键词：PEI/f-DNA polyplex plant cell transfection SAFFRON sonication

Development of fluorinated polyplex nanoemulsions for improved small interfering RNA delivery and cancer therapy被引量：2: 《Nano Research》2018年第7期3746-3761,共16页Gang Chen Kaikai Wang Pengkai Wu Yixin Wang Zhanwei Zhou Lifang Yin Minjie Sun David Oupicky; This work was financially supported by the National Science and Technology Major Project （No. 2017YFA0205400）, the Changjiang Scholar program, the National Natural Science Foundation of China （Nos. 81373983 and 81573377）, China Postdoctoral Science Foundation （No. 2016M601923）, and Postgraduate Research ＆ Practice Innovation Program of Jiangsu Province （No. KYCX17_0671）.; We report the development of a small interfering RNA （siRNA） delivery vector based on cationic perfluorocarbon nanoemulsions. We have prepared perfluorodecalin （PFD） emulsions with a positive surface charge provid...; 关键词：POLYPLEXES fluorous interactions small interfering RNA（siRNA） delivery tumor deliver perfluorocarbon emulsion

Polyplex在印尼建造PET薄膜装置: 《聚酯工业》2017年第6期43-43,共1页钱伯章; 泰国Polyplex有限公司（PCL）的子公司Polyplex公共有限公司（PTL）于2017年8月4日宣布,将投资9 500万美元在印度尼西亚建造一个聚对苯二甲酸乙二醇酯（PET）薄膜装置。; 关键词：薄膜 POLYPLEX 印度尼西亚生产能力项目计划月内伯章

核酸载体lipopolyplex的制备及细胞毒性研究: 《现代生物医学进展》2015年第27期5204-5207,共4页张士荣冯佳陈顺白光车俊怡吴飞; 国家自然科学基金项目(81373352); 目的:为降低聚阳离子基因载体polyplex的正电荷和毒性,在其表面构建中性磷脂膜制备lipopolyplex,并测定lipopolyplex对小鼠结肠癌细胞CT26和人乳腺癌细胞MCF-7的细胞毒性。方法:采用PEI25KDa与DNA复合制备polyplex,在polyplex体系中加...; 关键词：POLYPLEX 中性磷脂 Lipopolyplex ZETA电位细胞毒性

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