Supported by the CMC Vellore FLUID grant,No.10360.
BACKGROUND Multiple genetic risk factors for Crohn’s disease(CD)have been identified.However,these observations are not consistent across different populations.The protein tyrosine phosphate non-receptor type 2(PTPN2...
results in part from collaboration and network activities promoted under the frame of the international network GENIEUR (Genes in Irritable Bowel Syndrome Research Network Europe),which has been funded by the COST program (BM1106, www.GENIEUR.eu);currently supported by the European Society of Neurogastroenterology and Motility (ESNM, www.ESNM.eu)
BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bo...
Gastric adenocarcinoma is a global health concern,and Helicobacter pylori(H.pylori)infection is the main risk factor for its occurrence.Of note,the immune response against the pathogen seems to be a determining factor...
funded by grants from the National Natural Science Foundation of China[Grant No.81573507];the National Natural Science Foundation of China[Grant No.81473283];the National Natural Science Foundation of China[Grant No.81173131];the National Natural Science Foundation of China[Grant No.81320108027];the Natural Major Projects for Science and Technology Development from Science and Technology Ministry of China[Grant No.2012ZX09506001-004];the Major Scientific and Technological Project of Guangdong Province,China[Grant No.2011A080300001].
Background:Trough levels of the post-induction serum infliximab(IFX)are associated with short-term and long-term responses of Crohn’s disease patients to IFX,but the inter-individual differences are large.We aimed to...
Supported by Fundação de AmparoàPesquisa do Estado de Minas Gerais,No.APQ-02233-14.
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is becoming the most common chronic liver disease worldwide,with significant morbidity associated with nonalcoholic steatohepatitis(NASH).Genome-wide association studi...
Supported by the Sao Paulo Research Foundation,No2013/14022-6 and No.2014/17716-1
BACKGROUND Toll-like receptor-2(TLR2) is responsible for recognizing Helicobacter pylori(H.pylori) and activating the immune response. Polymorphisms in TLR2 may modulate gastric carcinogenesis.AIM To evaluate whether ...
Supported by The Sao Paulo Research Foundation(FAPESP),NO.2013/14022-6 and NO.2014/17716-1
BACKGROUND Toll-like receptors(TLRs)are the first line of host defense,and are involved in Helicobacter pylori(H.pylori)recognition and activation of both inflammatory and carcinogenic processes.The presence of single...
Non-alcoholic fatty liver disease(NAFLD) has a prevalence of approximately 30% in western countries, and is emerging as the first cause of liver cirrhosis and hepatocellular carcinoma(HCC). Therefore, risk stratificat...
Sorafenib has been considered the standard of care for patients with advanced unresectable hepatocellular carcinoma(HCC) since 2007 and numerous studieshave investigated the role of markers involved in the angiogenesi...
Ethical approval was given by the medical ethics committee of Sichuan University with the following reference number:2012-001-1.
Heavy alcohol drinking is a major public health problem,causing a large disease,social and economic burden in societies.Subjective response (SR) to alcohol is an intermediate characteristic of heavy drinking.A variety...
条 记 录，以下是1-10
