RIFAXIMIN

作品数:55被引量:289H指数:11
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相关领域:医药卫生更多>>
相关作者:任淑萍陈瑞玲更多>>
相关机构:首都医科大学附属北京天坛医院南昌大学更多>>
相关期刊:《国外药讯》《World Journal of Hepatology》《Open Journal of Gastroenterology》《Current Medical Science》更多>>
相关基金:国家自然科学基金更多>>
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Evolution of care in cirrhosis: Preventing hepatic decompensation through pharmacotherapy被引量:1
《World Journal of Gastroenterology》2023年第1期61-74,共14页Seohyuk Lee Saad Saffo 
Cirrhosis is a leading cause of morbidity and mortality,impacting more than 120 million people worldwide.Although geographic differences exist,etiologic factors such as alcohol use disorder,chronic viral hepatitis inf...
关键词:CIRRHOSIS Hepatic decompensation BETA-BLOCKERS STATINS Sodium-glucose cotransporter-2 inhibitors RIFAXIMIN 
Dual therapy with zinc acetate and rifaximin prevents from ethanolinduced liver fibrosis by maintaining intestinal barrier integrity被引量:7
《World Journal of Gastroenterology》2021年第48期8323-8342,共20页Yuki Fujimoto Kosuke Kaji Norihisa Nishimura Masahide Enomoto Koji Murata Soichi Takeda Hiroaki Takaya Hideto Kawaratani Kei Moriya Tadashi Namisaki Takemi Akahane Hitoshi Yoshiji 
BACKGROUND Hepatic overload of gut-derived lipopolysaccharide dictates the progression of alcoholic liver disease(ALD)by inducing oxidative stress and activating Kupffer cells and hepatic stellate cells through toll-l...
关键词:Liver fibrosis Intestinal permeability Alcoholic liver disease LIPOPOLYSACCHARIDE Toll-like receptor Tight junction protein 
Current approach to treatment of minimal hepatic encephalopathy in patients with liver cirrhosis被引量:12
《World Journal of Gastroenterology》2021年第22期3050-3063,共14页Segundo Moran Marlene López-Sánchez María del Pilar Milke-García Gustavo Rodríguez-Leal 
Supported by the Mexican Institute of Social Security,No.FFIS/IMSS/PROT/G16/1589;National Council for Science and Technology(CONACYT),No.SALUD-2014-C01-233823.
Minimal hepatic encephalopathy(MHE)corresponds to the earliest stage of hepatic encephalopathy(HE).MHE does not present clinically detectable neurological-psychiatric abnormalities but is characterized by imperceptibl...
关键词:Minimal hepatic encephalopathy SARCOPENIA PROBIOTICS Non-absorbable disaccharides Rifaximin L-ornithine-L-aspartate 
Prognostic significance of hepatic encephalopathy in patients with cirrhosis treated with current standards of care被引量:5
《World Journal of Gastroenterology》2020年第18期2221-2231,共11页Anuj Bohra Thomas Worland Samuel Hui Ryma Terbah Ann Farrell Marcus Robertson 
BACKGROUND Hepatic encephalopathy(HE)is a reversible neuropsychiatric complication of liver cirrhosis and occurs in up to 50%of cirrhotic patients.Studies examining the prognostic significance of HE are limited despit...
关键词:Hepatic encephalopathy CIRRHOSIS Portal hypertension PROGNOSIS RIFAXIMIN LACTULOSE 
Rifaximin improves survival in cirrhotic patients with refractory ascites: A real-world study被引量:13
《World Journal of Gastroenterology》2020年第2期199-218,共20页Xin-Yue Lv Hui-Guo Ding Jun-Fu Zheng Chun-Lei Fan Lei Li 
Supported by the State Key Projects Specialized on Infectious Diseases,No.2017ZX10203202-004 and No.2017ZX10203202003008;the Digestive Medical Coordinated Development Centre of the Beijing Municipal Administration of Hospitals,No.XXZ0303;Beijing High-level Health Technicians,No.2013-03-073;Beijing Municipal Administration of Hospitals’Ascent Plan,No.DFL20151602
BACKGROUND Rifaximin has been shown to reduce the incidence of hepatic encephalopathy and other complications in patients with cirrhosis.However,few studies have investigated the effect of rifaximin in cirrhotic patie...
关键词:RIFAXIMIN CIRRHOSIS Refractory ascites Inflammatory factors Gut microbiota Metagenomics sequencing 
Current and future pharmacological therapies for managing cirrhosis and its complications被引量:21
《World Journal of Gastroenterology》2019年第8期888-908,共21页David Kockerling Rooshi Nathwani Roberta Forlano Pinelopi Manousou Benjamin H Mullish Ameet Dhar 
Supported by The Division of Integrative Systems Medicine and Digestive Disease at Imperial College London receives financial support from the National Institute for Health Research(NIHR)Imperial Biomedical Research Centre(BRC)based at Imperial College Healthcare NHS Trust and Imperial College London;funded by the NIHR BRC
Due to the restrictions of liver transplantation,complication-guided pharmacological therapy has become the mainstay of long-term management of cirrhosis.This article aims to provide a complete overview of pharmacothe...
关键词:CIRRHOSIS BETA-BLOCKERS RIFAXIMIN DIURETICS STATINS Proton pump inhibitors Pharmacology 
Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity被引量:15
《World Journal of Gastroenterology》2017年第47期8355-8366,共12页Kosuke Kaji Hiroaki Takaya Soichiro Saikawa Masanori Furukawa Shinya Sato Hideto Kawaratani Mitsuteru Kitade Kei Moriya Tadashi Namisaki Takemi Akahane Akira Mitoro Hitoshi Yoshiji 
AIM To determine the efficacy of rifaximin for hepatic encephalopathy(HE) with the linkage of gut microbiome in decompensated cirrhotic patients.METHODS Twenty patients(12 men and 8 women; median age, 66.8 years; rang...
关键词:gut microbiome Hepatic encephalopathy Liver cirrhosis ENDOTOXIN RIFAXIMIN 
Eubiotic properties of rifaximin: Disruption of the traditional concepts in gut microbiota modulation被引量:24
《World Journal of Gastroenterology》2017年第25期4491-4499,共9页Francesca Romana Ponziani Maria Assunta Zocco Francesca D’Aversa Maurizio Pompili Antonio Gasbarrini 
Antibiotics are usually prescribed to cure infections but they also have significant modulatory effects on the gut microbiota. Several alterations of the intestinal bacterial community have been reported during antibi...
关键词:Intestinal bacteria Antibiotic RIFAXIMIN Gut microbiota Eubiosis DYSBIOSIS Gut microbiota modulation 
Use of rifaximin in gastrointestinal and liver diseases被引量:9
《World Journal of Gastroenterology》2016年第29期6638-6651,共14页Rani H Shayto Rachel Abou Mrad Ala I Sharara 
Rifaximin is a broad spectrum oral antibiotic with antimicrobial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is poorly absorbed and thus has a highly favorable safety profile. R...
关键词:Irritable bowel syndrome Inflammatory bowel disease Hepatic encephalopathy Bacterial overgrowth Diverticular disease 
Effect of rifaximin on gut microbiota composition in advanced liver disease and its complications被引量:19
《World Journal of Gastroenterology》2015年第43期12322-12333,共12页Francesca Romana Ponziani Viviana Gerardi Silvia Pecere Francesca D'Aversa Loris Lopetuso Maria Assunta Zocco Maurizio Pompili 
Liver cirrhosis is a paradigm of intestinal dysbiosis. The qualitative and quantitative derangement of intestinal microbial community reported in cirrhotic patients seems to be strictly related with the impairment of ...
关键词:Liver CIRRHOSIS GUT MICROBIOTA RIFAXIMIN HEPATIC e 
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