supported by grants from the National Key R&D Program of China(2021YFE0114200,2018YFC2000100);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-050);the Project funded by China Postdoctoral Science Foundation(2023M732704);the National Natural Science Foundation of China(81770228,82370584,81470427 and U23A20470);the Beijing Natural Science Foundation(7232141,7212086);the Beijing Hospital Clinical Research 121 Project(121-2016004);the National High Level Hospital Clinical Research Funding(BJ-2021-199,BJ-2023-156,BJ-2019-159).
DEAD-box helicase 17(DDX17)is a typical member of the DEAD-box family with transcriptional cofactor activity.Although DDX17 is abundantly expressed in the myocardium,its role in heart is not fully understood.We genera...