supported by National Natural Science Foundation of China(81991500,81991503);Cross-disciplinary Research Fund of Shanghai Ninth People's Hospital,Shanghai JiaoTong University School of Medicine(JYJC201904);Science and Technology Commission of Shanghai Municipality(18ZR1422400);Innovative Research Team of High-level Local Universities in Shanghai(SSMU-ZDCX20180900);Open Project of the Key Laboratory of Rehabilitation Medicine in Sichuan Province of China(KFYXSZDSYS-01);the Natural Science Foundation of Sichuan Province of China(2022NSFSC1469).
Peri-implant lesion is a grave condition afflicting numerous individuals with dental implants.It results from persistent periodontal bacteria accumulation causing inflammation around the implant site,which can primari...
supported by the National Key Research and Development Program of China(2021YFB3802100,2021YFB3802105);Major Project of Sichuan Science and Technology Department(2022ZDZX0029);the International Science and Technology Innovation Cooperation Project of Sichuan Province(2021YFH0131);National Natural Science Foundation of China(52002256);the Science and Technology Cooperation Program of Sichuan University and Panzhihua City(2021);Sichuan University‘Zero to one’Innovation Research Project(0082604151276).
Calcium phosphate(CaP)bioceramics are widely applied in the bone repairing field attributing to their excellent biological properties,especially osteoinductivity.However,their applications in load-bearing or segmental...
This study aimed at evaluating the possibility and effectiveness of osteoinductive bioceramics to fill the tumor cavity following the curettage of sacral giant cell tumor(GCT).Six patients(four females and two males,2...
supported by the National key Research and Development Program of China(2021YFA0715700);the Natural Science Foundation of China(32130062);Shanghai Pilot Program for Basic Research-Chinese Academy of Science,Shanghai Branch(JCYJ-SHFY-2022-003).
For the research of biomaterials in bone tissue engineering,it is still a challenge to fabricate bioceramics that overcome brittleness whilemaintaining the great biological performance.Here,inspired by the toughness o...
This work was supported by the Natural Science Foundation of China[Grant No.31271054 and 31770980].
Human bone marrow stem cells(hBMSCs)are exploited for miscellaneous applications in bone tissue engineering where they are mainly used as seed cells.However,high glucose(HG)environment has negative impacts on the prol...
the Sichuan Provincial STP(No.2017JY0018);the National Basic Research Program of China(973 Program,No.2012CB933600).
Collagen(COL),collagen/hydroxyapatite(COL/HA),HA and biphasic calcium phosphate were prepared as representative bone grafting materials with composition analogous to bone,and their structural characteristics were anal...
supported through funds provided by the PNR-CNR Aging Program 2012-2014.
This study concerns the synthesis of gel materials based on carbon nanotubes dispersed strontium-modified hydroxyapatite(Sr-HA)at different compositions obtained by sol–gel technology and their influence on human-bon...
This work was supported by the Department of Defense for their sponsorship through grant DAMD W81XWH11-10262 and funding from the Raymond and Beverly Sackler Center for Biomedical,Biological,Physical and Engineering Sciences.
Bone is an essential organ for health and quality of life.Due to current shortfalls in therapy for bone tissue engineering,scientists have sought the application of synthetic materials as bone graft substitutes.As a c...