AQUAPORIN-4

作品数：63被引量：217H指数：9
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相关领域：医药卫生更多>>
相关作者：沙洛林李红闪史彦芳郭毅马睿泽更多>>
相关机构：南京医科大学中山大学附属第三医院河北大学北华大学更多>>
相关期刊：《World Journal of Neurology》《Neural Regeneration Research》《中国药理通讯》《神经损伤与功能重建》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金北京市自然科学基金更多>>
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Relationship Between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood-brain Barrier Disruption in Mice and Its Possible Mechanism:Role of Aquaporin-4 and Connexin43被引量：5
《Neuroscience Bulletin》2020年第11期1369-1380,共12页Heling Chu Zidan Gao Chuyi Huang Jing Dong Yuping Tang Qiang Dong 
grants from the National Natural Science Foundation of China(81500998 and 81901102);the Science and Technology Commission of Shanghai Municipality(16140903200);Shanghai Sixth People’s Hospital Medical Group(2017LY01);the Research Fund of Shanghai Tongren Hospital,Shanghai Jiaotong University School of Medicine(TRYJ201701);the Research Fund of North Huashan Hospital,Fudan University(HSBY2019004)。
We aimed to select an optimized hematoma expansion(HE)model and investigate the possible mechanism of blood-brain barrier(BBB)damage in mice.The results showed that HE occurred in the group with hypertension combined ...
关键词：Intracerebral hemorrhage Hematoma expansion Animal model Blood-brain barrier AQUAPORIN-4 CONNEXIN43 
Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinct from Astrocytopathy Induced by AQP4-IgG被引量：16
《Neuroscience Bulletin》2019年第5期853-866,共14页Ling Fang Xinmei Kang Zhen Wang Shisi Wang Jingqi Wang Yifan Zhou Chen Chen Xiaobo Sun Yaping Yan Allan G. Kermode Lisheng Peng Wei Qiu 
supported by grants from the National Natural Science Foundation of China (81471218 and 81771300);the Natural Science Foundation of Guangdong Province, China (2017A030313853)
Immunoglobulin G against myelin oligodendrocyte glycoprotein(MOG-Ig G) is detectable in neuromyelitis optica spectrum disorder(NMOSD) without aquaporin-4 Ig G(AQP4-Ig G), but its pathogenicity remains unclear.In this ...
关键词：Neuromyelitis optica spectrum disorder AQUAPORIN-4 IMMUNOGLOBULIN G MYELIN OLIGODENDROCYTE glycoprotein IMMUNOGLOBULIN G Complement-dependent cytotoxicity Transmission electron microscopy 
Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain被引量：6
《Neuroscience Bulletin》2012年第1期61-68,共8页Wen-Zhen Shi Chun-Zhen Zhao Bing Zhao Xiao-Liang Zheng San-Hua Fang Yun-Bi Lu Wei-Ping Zhang Zhong Chen Er-Qing Wei 
supported by the National Natural Science Foundation of China (81072618,30772561,30873053 and 30672449);the Natural Science Foundation of Zhejiang Province,China (Y2090069);the "Qian Jiang Ren Cai Research Plan" Zhejiang Province,China (2010R10055);Fundamental Research Funds for the Central Universities of China (2009QNA7008)
Objective To determine whether aquaporin-4 （AQP4） regulates acute lesions, delayed lesions, and the associated microglial activation after cryoinjury to the brain. Methods Brain cryoinjury was applied to AQP4 knocko...
关键词：AQUAPORIN-4 gene deficiency CRYOINJURY microglia ASTROCYTE 
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