The aim of the study was to assess the distribution of connexin43 (Cx43) and connexin40 (Cx40) in human and bovine ciliary bodies. The effect of the second messengers cAMP and cyclic cGMP on Cx43 protein expression wa...
supported in part by a research grant from Novo Nordsik(USA,to Philipp E.Scherer);by NIH Grants(USA)R01-DK55758,R01-DK099110,R01-DK127274,R01DK131537 and P01-AG051459 to Philipp E.Scherer,NIH Grant R00-DK114498;NIH Grant K99-AG068239 to Shangang Zhao;NIH Grant K01-DK125447 to Yu A.An;NIH grants R01 DK119169 and P01 DK119130-5830 to Kevin W.Williams;USDA ARS(cooperative agreement 309251000-062)to Yi Zhu;AHA Career Development Award 855170(USA)to Qingzhang Zhu。
Adipose tissue is a promising target for treating obesity and metabolic diseases.However,pharmacological agents usually fail to effectively engage adipocytes due to their extraordinarily large size and insufficient va...
This work was supported by the grants from the National Natural Science Foundation of China(Nos.81600840 and 81771047 to J.X.and No.81900965 to W.D.).
Osteocytes are the main sensitive cells in bone remodeling due to their potent functional cell processes from the mineralized bone matrix to the bone surface&the bone marrow.Neighboring osteocytes communicate with eac...
supported by National Key R&D Program of China(No.2017YFE0102200);the National Natural Science Foundation of China(No.81573426);the State Key Program of National Natural Science Foundation of China(No.81730101);Public Welfare Project of Zhejiang Provincial Science and Technology Department(No.LGF21H310005).
Rictor is a key component of the mammalian target of rapamycin complex 2(mTORC2)and is required for Akt phosphorylation(Ser473).Our previous study shows that knockdown of Rictor prevents cardiomyocyte differentiation ...