Financial support from the National Natural Science Foundation of China(No.81773746);the Open Project of Hubei Key Laboratory of Wudang Local Chinese Medicine Research,Hubei University of Medicine(No.WDCM009 and 2011JH-2014CXTT07);the Foundation of Health and Family planning Commission of Hubei Province(No.WJ2015Z113);the Foundation for Innovative Research Team of Hubei University of Medicine(2014CXZ01 and 2014CXZ05)
A series of 2-acyl-β-lactam-2-carboxamides was prepared through a tandem Ugi 4 CC/SN cyclization of bromoacetic acid, primary amine, arylglyoxal, and isocyanide. All of them were characterized by NMR, IR, MS and elem...
Supported by the Natural Foundation of Hebei Province
The title compound -(N-protected amino)--lactam (C36H33N2O5ClS), derivative of 1,5-benzothiazepine, was prepared by the reaction of 1,5-benzothiazepine 1 with (4R)- phenyloxazolidylacetyl chloride and characteized by ...
The crystal of the title compound C, C 30 H 30 N 2O 3S has been prepared by reaction of 1,5 benzothiazepine with N protected glycine and determined by X ray single crystal diffraction. Crystal data:...
The compound(2) (C 24 H 20 NO 2ClS)(see Scheme 1) has been synthesized by reaction of 1, 5 benzothiazepine with chloroacetyl chloride and crystallized in the monoclinic system, space group P2 1/c, a=12.54...