RENEWAL

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rtcisE2F promotes the self-renewal and metastasis of liver tumorinitiating cells via N^(6)-methyladenosine-dependent E2F3/E2F6 mRNA stability被引量：4
《Science China(Life Sciences)》2022年第9期1840-1854,共15页Zhenzhen Chen Lan Huang Kaili Wang Lulu Zhang Xiang Zhong Zhongyi Yan Benyu Liu Pingping Zhu 
This work was supported by the National Natural Science Foundation of China(31922024,81872411,32170874,82173176);Science Foundation for Excellent Young Scholars in Henan(202300410358).
Liver cancer is highly heterogeneous,and the tumor tissue harbors a variety of cell types.Liver tumor initiating cells(TICs)well contribute to tumor heterogeneity and account for tumor initiation and metastasis,but th...
关键词：circular RNA tumor-initiating cells SELF-RENEWAL METASTASIS N^(6)-methyladenosine 
Identification of microRNA transcriptome reveals that miR-100 is involved in the renewal of porcine intestinal epithelial cells被引量：10
《Science China(Life Sciences)》2019年第6期816-828,共13页Lijun Zou Xia Xiong Huansheng Yang Kexing Wang Jian Zhou Dinghong Lv Yulong Yin 
supported by the Key Programs of Frontier Scientific Research of the Chinese Academy of Sciences (QYZDYSSW-SMC008);National Program on Key Basic Research Project (2016YFD0500504);National Nature Science Foundation of China (31330075; 31572420);Hunan Provincial Natural Science Foundation of China (2018JJ3094; 2018JJ1028);Research Foundation of Education Bureau of Hunan Province, China (18B476);Hunan Provincial Innovation Foundation for Postgraduate (CX2016B172)
MicroRNAs play important roles in various cellular processes, including differentiation, proliferation and survival. Using a pig model, this study sought to identify the miRNAs responsible for crypt-villus axis renewa...
关键词：MicroRNAs SUCKLING PIGLETS crypt-villus axis cell RENEWAL IPEC-J2 cells 
Paracrine signaling in stem cell renewal and in neoplastic tumor growth被引量：2
《Science China(Life Sciences)》2014年第6期571-574,共4页ZHAO Chen 
Paracrine pathway activities are being increasingly recognized as instrumental regulatory mechanisms of epithelial-stromal interactions that play important roles in physiological and pathological self-renewal of stem ...
关键词：HEDGEHOG Wnt PARACRINE stem cell tumor 
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