PHENYLGLYCINE

作品数：6被引量：4H指数：1
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相关领域：理学医药卫生更多>>
相关期刊：《Science Bulletin》《Current Medical Science》《Chemical Research in Chinese Universities》《Synthetic and Systems Biotechnology》更多>>
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A Concise,Practical Chiral Resolution Approach of Racemic (E)-4,4-Dimethyl-1-(4-nitrophenyl) pent-1-en-3-ol to Its both Enantiomers via Strategy of Diastereomeric Ester Formation and Crystallization Using both N-Boc-D- and N-Boc-L-phenylglycines as Chiral Auxiliaries
《Chemical Research in Chinese Universities》2024年第6期1096-1105,共10页JIANG Shanshan YUAN Jia QIN Yanlan LUO Ying JIN Zhengsheng ZHAO Guilong TI Huihui 
supported by the Guangdong Basic and Applied Basic Research Foundation,China (Nos.2021A1515010197,2023A1515012259);the Zhongshan Municipal Natural Science Foundation,China (Nos.200805173640573,210730214049987,221018194369472);the Project of the Creative Research Group of Zhongshan City,China (No.CXTD2022011);Dazhou Applied Basic Research Foundation,China (No.23YYJC0002).
Chiral secondary alcohols are an important class of functionalities commonly seen in drugs and other bioactive compounds.In an ongoing drug discovery program in our laboratories,a nitro-bearing racemic allylic seconda...
关键词：Chiral resolution PHENYLGLYCINE Chiral auxiliary Chiral secondary alcohol Diastereomeric ester formation 
Improved L -phenylglycine synthesis by introducing an engineered cofactor self-sufficient system
《Synthetic and Systems Biotechnology》2022年第1期513-521,共9页Pengchao Wang Xiwen Zhang Yucheng Tao Xubing Lv Shengjie Cheng Chengwei Liu 
the National Natural Science Foundation of China(Project No.31900064);as well as the Natural Science Foundation of Heilongjiang Province of China(Project No.LH2019C012)。
L-phenylglycine(L-phg)is a valuable non-proteinogenic amino acid used as a precursor to β-lactam antibiotics,antitumor agent taxol and many other pharmaceuticals.L-phg synthesis through microbial bioconversion allows...
关键词：L-phenylglycine Whole-cell biocatalyst Self-sufficient Protein scaffold Hydroxymandelate synthase 
Role of the Notch Signaling Pathway in Fibrosis of Denervated Skeletal Muscle
《Current Medical Science》2019年第3期419-425,共7页Fei FENG Lu SHAN Jing-xiu DENG Ling-li LUO Qi-shun HUANG 
In order to investigate the role of the Notch signaling pathway in skeletal muscle fibrosis after nerve injury, 60 Sprague-Dawley rats were selected and divided randomly into a control and two experimental groups. Gro...
关键词：NOTCH signaling pathway SCIATIC nerve skeletal muscle FIBROSIS N-[N-(3 5- difluorophenacetyl)-l-alanyl]-S-phenylglycine T-BUTYL ester NOTCH 1 JAGGED 1 Hes 1 collagen I denervated muscular atrophy 
Fabrication and adsorption property of novel adsorbent for potential application to wastewater with Fe(Ⅲ) ions被引量：1
《Journal of Central South University》2014年第7期2832-2836,共5页朱卫霞 宋航 贾春梅 姚舜 
Projects(81373284,81102344) supported by the National Natural Science Foundation of China
The spherical macroporous cellulose(SMC) was fabricated using medical absorbent cotton as raw material and nano CaCO3 as porogenic agents.And then,the phenylglycine was grafted onto the SMC to obtain the novel spheric...
关键词：cellulose modified with phenylglycine adsorption Fe（Ⅲ） ions porogenic agent kinetic and isotherm 
Characteristic fragmentation behavior of the analogs of endomorphin-2 with phenylglycine in position 3 or 4 by ESI-FT tandem mass spectrometry
《Chinese Chemical Letters》2008年第12期1479-1482,共4页Chang Feng Hu Chuan Jun Zhu Yan Feng Gao Xuan Shao Rui Wang Yu Xin Cui 
A series of analogs of endomorphin-2 （EM-2） with phenylglycine （Phg） in position 3 or 4 were synthesized. In electrospray ionization Fourier transform ion cyclotron resonance （ESI-Fr-ICR） MS/MS spectra of these ...
关键词：Endomorphin-2 Opioid peptide analogs PHENYLGLYCINE ESI-FT MS 
廖笳因(Chia-Yin Liao) 廖永豐(Yung-Feng Liao) 王柏堅(Bo-Jeng Wang) 黃詩雅(Shy-Ya Huang) 胡明寬(Ming-Kuan Hu) 
Application of modified amino acid as a chiral building block in asymmetric synthesis被引量：3
《Chinese Science Bulletin》2001年第23期1952-1956,共5页WANG Jianping ZHANG Xiyun CHEN Qinghua 
This work was supported by the National Natural Science Foundation of China (Grant No. 29672004).
Phenylglycine 1 as a representative of natural resourceful a-amino acid was modified by reduction and protection of functional group to afford the amino alcohol as a chiral building block 3. A new chiral compound, the...
关键词：MODIFIED α-amino acid PHENYLGLYCINE AMINO alcohol chiral building block spiro-cyclopropane derivative STEREOCHEMISTRY and absolute configuration. 
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