BLOOD-BRAIN-BARRIER

作品数:5被引量:15H指数:2
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相关领域:医药卫生更多>>
相关作者:陈鸿光崔广强赵炜汤国太更多>>
相关机构:烟台毓璜顶医院更多>>
相关期刊:《Genes & Diseases》《Chinese Medical Journal》《World Journal of Clinical Infectious Diseases》《Health》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Targeting metastatic breast cancer with ANG1005, a novel peptide-paclitaxel conjugate that crosses the blood-brain-barrier (BBB)被引量:3
《Genes & Diseases》2017年第1期1-3,共3页Fei Li Shou-Ching Tang 
We devoted this short interview piece with Dr Shou-Ching Tang at Augusta University to feature some promising results from a clinical phase II trial on a novel brain-penetrating peptide-paclitaxel-conjugate,ANG1005,in...
关键词:ANG1005 Brain metastasis Breast cancer LRP-1 The blood-brain-barrier 
Interplay between rabies virus and the mammalian immune system
《World Journal of Clinical Infectious Diseases》2015年第4期67-76,共10页Nicholas Johnson Adam F Cunningham 
Supported by The European Union Seventh Framework Programme through project ANTIGONE:Anticipating the global onset of novel epidemics,No.278976
Rabies is a disease caused following infection of the brainby the rabies virus(RABV). The principle mechanism of transmission is through a bite wound. The virus infects peripheral nerves and moves to the central nervo...
关键词:RABIES virus Immune STIMULATION Central nervous system VACCINATION BLOOD-BRAIN-BARRIER 
Evaluation of oxidative and nitrosative stress in relapsing remitting multiple sclerosis
《Health》2013年第11期1924-1928,共5页Stefan Lukac Terezia Kalnovicova Jana Muchova 
Multiple sclerosis (MS) is a chronic autoimmune disorder affecting the central nervous system (CNS) through demyelination and neurodegeneration. Several lines of evidence support a role for oxidative and nitrative str...
关键词:Relapsing Remiting Multiple Sclerosis Oxidative Stress Nitrative Stress BLOOD-BRAIN-BARRIER Total Antioxidant Status 3-NITROTYROSINE Protein Carbonyls Lipoperoxides Uric Acid 
Detrimental Effect of Electromagnetic Pulse Exposure on Permeability of In Vitro Blood-brain-barrier Model被引量:10
《Biomedical and Environmental Sciences》2013年第2期128-137,共10页ZHOU Jia Xing DING Gui Rong ZHANG Jie ZHOU Yong Chun ZHANG Yan Jun GUO Guo Zhen 
supported by the National Basic Research Program of China(2011CB503704,2011CB503705);National Natural Science Foundation of China (No. 30970670, 60871068)
Objective To study the effect of electromagnetic pulse (EMP) exposure on permeability of in vitro blood-brain-barrier (BBB) model. Methods An in vitro BBB model, established by co-culturing brain microvascular end...
关键词:Electromagnetic pulse BLOOD-BRAIN-BARRIER PERMEABILITY TEER HRP ZO-1 CLAUDIN-5 
Opening blood-brain-barrier by intracarotid infusion of papaverine in treatment of malignant cerebral glioma被引量:2
《Chinese Medical Journal》1998年第8期79-81,共3页薛洪利 王辉 孔令权 周怀伟 
Abstract: Objective To find an effective method for the treatment of malignant cerebral glioma by opening the bloodbrainbarrier (BBB).Methods The concentration of methotrexate (MTX) in tumor was measured in 18 pa...
关键词:INFUSION PAPAVERINE intracarotid TREATMENT OPENING BLOOD-BRAIN-BARRIER 
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