support from the National Natural Science Foundation of China(grant nos.22021002,22020102005,and 22022705);the CAS-Croucher Funding Scheme for Joint Laboratories.
The direct cleavage of C–NO_(2)bonds for reductive denitration of nitroarenes remains a challenging transformation in synthetic organic chemistry.Herein,we report a biocompatible palladium-deposited graphdiyne nanoca...
supported by the Natural Science Foundation of Anhui Province,China,No.1608085MH209(to YBW);New Medicine of University of Science and Techology of China,No.WK110000036(to YBW)
A high glucose state readily causes peripheral axon atrophy, demyelination, loss of nerve fiber function, and delayed regeneration. However, few studies have examined whether nitration is also critical for diabetic pe...
supported by the Army on the Subject of China (10ZYZ219)
Background: To investigate the effects of unsafe decompression on rat pulmonary endothelial function and its relevant mechanisms.Methods: Sixty male Sprague-Dawley(SD) rats were randomly divided into a control group(n...
A novel method for the simultaneous determination of 3-nitrotyrosine(NT) and 3-chlorotyrosine(CT) in human plasma has been developed based on direct analysis in real time–tandem mass spectrometry(DART–MS/MS). Analys...
Multiple sclerosis (MS) is a chronic autoimmune disorder affecting the central nervous system (CNS) through demyelination and neurodegeneration. Several lines of evidence support a role for oxidative and nitrative str...
Objective: Myeloperoxidase (MPO) is an inflammatory enzyme that is mainly released by activated neutrophils and monocytes. 3-nitrotyrosine (NT) is a stable inflammatory end product of MPO that is produced through nitr...
Supported by the National Basic Research Program of China(Nos.2012CB721105,2011CBA00802,2007CB714301);the National Natural Science Foundation of China(No.30873400);the Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20090032110015)
In vitro antioxidant activities of resveratrol and piceid against peroxynitrite(ONOO-) were examined by the inhibition of 3-nitrotyrosine formation.Trolox was used as a positive control.Resveratrol and piceid exhibi...
The authors would like to thank the financial support from the National Natural Science Foundation of China (No. 20320130046) ;the Specialized Research Fund for the Doctoral Program of Higher Education (SRFDP) of M0E (No. 20030003049).
Hydroxylation of 3-nitrotyrosine (3-NT) and 3-NT containing peptide Gly-nitroTyr-Gly in aqueous solution by hydroxyl radical were investigated with gamma irradiation. The structures of the hydroxylated products were...