the National Natural Science Foundation of China(Nos.81941009,81991514,32271409,and 82202778);Nanjing Distinguished Youth Fund(No.JQX20001);Jiangsu Provincial Key R&D Program(No.BE2022836);China Postdoctoral Science Foundation(No.2020M671456);National Basic Research Program of China(No.2021YFA1201404);Jiangsu Provincial Key Medical Center Foundation,Jiangsu Provincial Medical Outstanding Talent Foundation,Jiangsu Provincial Medical Youth Talent Foundation and Jiangsu Provincial Key Medical Talent Foundation,and the Fundamental Research Funds for the Central Universities(Nos.14380493 and 14380494).
Background:Reactive oxygen species(ROS)is considered as ubiquitous and highly active chemicals that influence tendon integrity and orchestrate tendon repair.With significant recent advances in nanomaterials,cerium oxi...
Background:Adult stem cells have a remarkable capacity of differentiating into various cell types necessary for tissue and organ regeneration.Multiple studies have focused on the differentiation potential of mesenchym...
Supported by EPSRC Doctoral Training Centre in Regenerative Medicine and the HYANJI Scaffold Project (European Commission Framework 7 program)
AIM: To establish the potential of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) as a material for tendon repair. METHODS: The biocompatibility of PHBHHx with both rat tenocytes (rT) and human mesenchymal ste...
supported by the National Natural Science Foundation of China (30770886,30570369,30340038,30973158);National High Technology Research and Development Program of China (2007AA02Z105);Natural Science Foundation of Guangdong Province (04105826);Key Science and Technology Program of Guangdong Province (2004B3-0601007);Key Science and Technology Program of Guangzhou (2006Z3-E5251);the Fundamental Research Funds for the Central Universities(21609408)
The repair of injured tendons remains a great challenge because of the poor intrinsic healing capacity of tendons. In this study, we examined the spatiotemporal expression pattern of the bone morphogenetic protein 2 (...
The bFGF plays an important role in embryonic development of tendons and ligaments and in the healing of injuried tendons and ligaments. The eukaryotic expression plasmid of rat basic fibroblast growth factor (bFGF)...
To study the proliferation and collagen production of tendon sheath fibroblasts, epitenon tenocytes, and endotenon tenocytes; and the effects of chitosan on cell proliferation and collagen production in the 3 cell typ...
Objective To investigate the feasibility of tendon engineering in vitro using tenocyws and polyglycolic acids ( PGA ). Methods Tenocytes were isolated by tissue explant method and expanded in vitro. Cells of the sec...
AIM:To investigate the technique of tissue engineered tendon with human tenocy tes.METHODS:Human tenocytes in vitro, then the tenocytes were mixed with Polygly colic Acid(PGA) to form cell-polymer constructs and cultu...