supported by the National Natural Science Foundation of China(31871148,91639105,31571167,and 31571168).
Sympathetic activation and the kidney play critical roles in hypertension and chronic heart failure.The role of the kidney in sympathetic activation is still not well known.In this study,we revealed an excitatory rena...
We thank Bo Yuan and Tao Wang from the Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Beijing,China,for technical assistance.This work was supported by the National Natural Science Foundation of China(81771205,91632113);the Natural Science Foundation and Major Basic Research Program of Shanghai Municipality,China(16JC1420500 and 16JC1420502);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2017-I2M-3-008);the National Natural Science Foundation for Young Scientists of China(81600956).
Topical irritants such as capsaicin(CAP),peppermint oil(PO),and mustard oil(MO)are effective in relieving inflammatory muscle pain.We investigated the effects of topical irritants in a rat model of inflammatory muscle...
supported by grants from the National Natural Science Foundation of China (31671100, 31471022, 31622027, 31490592, 81527901, and 81521062);Zhejiang Provincial Natural Science Foundation, China (LR18H090001);the Program for Introducing Talents in Disciplines to Universities;the Fundamental Research Funds for the Central Universities, China (2017YFA7002, and 2019QNA5001)
The laterodorsal tegmentum(LDT) is a brain structure involved in distinct behaviors including arousal,reward, and innate fear. How environmental stimuli and top-down control from high-order sensory and limbic cortical...
supported by grants from the National Natural Science Foundation of China (31400946, 31671120, 31771197, 31329001, 31771156, 91632303, and 81661148053/H09);the Strategic Priority Research Program of Chinese Academy of Science (XDB32030200);the National Basic Research Development Program (973 Program) of China (2015CB755600)
Sensory processing is strongly modulated by different brain and behavioral states,and this is based on the top-down modulation.In the olfactory system,local neural circuits in the olfactory bulb(OB)are innervated by c...
During cerebral cortical cortex neurogenesis two major types of progenitors generate a variety of morphologically and functionally diverse projection neurons destined for the different cortical layers in non-gyrified ...
Supported by the National Natural Science Foundation of China (No.30870834);the Zhejiang Medical and Health Science Research Foundation(No.2008A042);the Zhejiang Provincial Natural Science Foundation of China(No.Y2110057 and No.Y2090820)
Objective: To assess the inhibitory modulation of blood pressure by stimulation of the deep peroneal nerve (DPN) and to determine the involvement of nociceptive fibers in the modulation. Methods: All the animals w...
Supported by Science and Technology Commission of Shanghai Municipality,No. 10ZR1417300;Educational Commission of Shanghai Municipality,No. 10ZZ69
AIM: To assess the role of hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels in regu- lating the excitability of vagal and spinal gut afferents. METHODS: The mechanosensory response of mese...
supported by Chongqing Science and Technology Commission (No.CHTC2007BA5025);Shanghai Pujiang Program (No.07PJ14015);Chongqing Educational Department (No. KJ0707021)
Objective Endogenous nitric oxide (NO) has been implicated in the regulation of neuronal activity which mediates cardiovascular reflexes. However, there is controversy concerning the role of NO in the nucleus tractu...
grants from the National Institutes of Health(NS-41269,NS-14447)
Diseases and injuries to the nervous system can lead to a devastating chronic pain condition called neuropathic pain.We review changes that occur in the peripheral nervous system that may play a role in this disease.C...
Object: In this study we investigated the effects of intrathecally administered TMP on the acute nociception mediated by the local administration of P2X receptor agonists ( ATP or α,β-meATP) or formalin in mouse hin...