FIBROGENESIS

作品数：46被引量：605H指数：15
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相关领域：医药卫生更多>>
相关作者：陈志南边惠洁李浩吴佼更多>>
相关机构：第四军医大学同济大学上海中医药大学更多>>
相关期刊：《Journal of Bio-X Research》《World Journal of Gastroenterology》《肝脏》《Current Medical Science》更多>>
相关基金：国家自然科学基金河北省自然科学基金上海市教育委员会重点学科基金广西壮族自治区自然科学基金更多>>
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Deciphering the role of transforming growth factor-beta 1 as a diagnostic-prognostic-therapeutic candidate against hepatocellular carcinoma被引量：5
《World Journal of Gastroenterology》2022年第36期5250-5264,共15页Aswathy R Devan Keechilat Pavithran Bhagyalakshmi Nair Maneesha Murali Lekshmi R Nath 
Supported by the Amrita Vishwa Vidyapeetham SEED grant (K-PHAR-22-662)
Transforming growth factor-beta(TGF-β)is a multifunctional cytokine that performs a dual role as a tumor suppressor and tumor promoter during cancer progression.Among different ligands of the TGF-βfamily,TGF-β1 mod...
关键词：Transforming growth factor-beta 1 Inflammation IMMUNOSUPPRESSION FIBROGENESIS Hepatocellular carcinoma Biomarker IMMUNOTHERAPY 
Silencing ofα-complex protein-2 reverses alcohol-and cytokine-induced fibrogenesis in hepatic stellate cells被引量：2
《Liver Research》2017年第1期70-79,共10页Hao Liu Zhijin Chen Wei Jin Ashutosh Barve Yu-Jui Yvonne Wan Kun Cheng 
This work was supported by an award(1R01AA021510)from the National Institutes of Health.
Background and aim:a-complex protein-2(aCP2)encoded by the poly(rC)binding protein 2(PCBP2)gene is responsible for the accumulation of type I collagen in fibrotic livers.In this study,we silenced the PCBP2 gene using ...
关键词：Hepatic stellate cells Primary HSC MYOFIBROBLAST Liver fibrosis Poly(rC)binding protein(PCBP)2 Transforming growth factor(TGF)-b Platelet-derived growth factor(PDGF) Epidermal growth factor(EGF) LY2a09761 Migration 
Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors被引量：39
《World Journal of Gastroenterology》2014年第36期12945-12955,共11页Paola Dongiovanni Stefano Romeo Luca Valenti 
Hepatocellular carcinoma(HCC) is the fourth cause of cancer related mortality, and its incidence is rapidly increasing. Viral hepatitis, alcohol abuse, and exposure to hepatotoxins are major risk factors, but nonalcoh...
关键词：Nonalcoholic fatty liver disease STEATOSIS Hepatocellular carcinoma CIRRHOSIS FIBROGENESIS Liver disease Genetics Single nucleotide polymorphism Patatin-like phospholipase domain-containing 3 
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