National Key Research and Development Program of China (2018YFA0902000);the key project at central government level:the ability establishment of sustainable use for valuable Chinese medicine resources(2060302,China);the open foundation of Shaanxi University of Chinese Medicine state key laboratory of R&D of Characteristic Qin Medicine Resources (SUCM-QM202202,China);the fund of Traditional Chinese Medicine Institute of Anhui Dabie Mountain (TCMADM-2023-18,China);National Natural Science Foundation of China (32070364);Hainan Provincial Natural Science Foundation of China(2019RC309)
Pyran-and furanocoumarins are key representatives of tetrahydropyrans and tetrahydrofurans,respectively,exhibiting diverse physiological and medical bioactivities.However,the biosynthetic mechanisms for their core str...
We are grateful for the financial support from the National Natural Science Foundation of China(No.21202154);Nanjing Institute of Technology Fund for Talents(No.YKJ201329);Nanjing Institute of Technology and the University of Science and Technology of China.
An unprecedented protocol has been developed for the efficient synthesis of substituted tetrahydropyrans via a bismuth-promoted Prins cyclization of imines with homoallyl alcohols.In the presence of 40 mol%BiCl_(3),a ...
the Key Foundation of the Ministry of Education of China ; National Natural Science Foundation of China(Grant No.20372033).
By investigating the effect of the amount of water, the ratio of aldehyde and allyl- bromide, and the reaction temperature on the transformation, 2,4,6-trisubstituted tetrahydro- pyrans are synthesized by a novel tand...
The construction of stereodefined, highly substituted tetrahydropyrans has attracted a lot of interest over the years since they constitute ubiquitous fragments of numerous biologically active natural products.[1]...