ACONITUM

作品数:111被引量:343H指数:10
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Rapid toxicity characterization of Aconitum herbal medicines using perfusion nano-electrospray ionization mass spectrometry
《Journal of Pharmaceutical Analysis》2024年第9期1393-1395,共3页Chaofa Wei Liping Kang Yaqiu Zhao Li Zhou Xiang Li Shuanglong Wang Luqi Huang Zidong Qiu 
supported by the CACMS Innovation Fund(Grant Nos.:CI2021A05206,and CI2021A04504);the National Natural Science Foundation of China(Grant No.:82104380);the Fundamental Research Funds for the Central Public Welfare Research Institutes(Grant No.:ZZ14-YQ-047);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(Grant Nos.:CI2023E002,and CI2023C039YGL).
Accurate analysis of the key substances in traditional Chinese medicines(TCMs)is the prerequisite and foundation for the quality evaluation and pharmacological substance research of TCMs[1].However,the extremely compl...
关键词:TCM FOUNDATION MEDICINES 
Inhibiting Effect and Mechanism of Aconitum tanguticum(Maxim.) Stapf on Intestinal Fibrosis of CCD-18Co Cells
《World Journal of Traditional Chinese Medicine》2024年第3期354-362,共9页Qin-Dan Cui Li-Dan Shen Yuan Bai Muhammad Azhar Jun Deng Xian-Ju Huang Hai-Ying Tong 
supported by grants provided by the National Natural Science Foundation of China (81873090);funding from the Research on Identification and Support Innovation and Development of Enterprise Technology Projects in Hubei Province (2021BLB174);the Modern Transmission and Innovation Research Team of Traditional Chinese Medicine at South Central Minzu University
Objective: The objective of the study was to explore the potential signaling mechanism of Aconitum tanguticum(Maxim.) Stapf(ATS) and its impact on intestinal fibrosis in vitro. Methods: Network pharmacology was used t...
关键词:Aconitum tanguticum(Maxim.)Stapf CCD‑18Co cells intestinal fibrosis network pharmacology transforming growth factor‑β/suppressor of the mother against decapentaplegic signal pathway 
A traditional formula of aconitum complex alleviates post-ischemic stroke by improving neural function
《Acta Biochimica et Biophysica Sinica》2024年第2期327-330,共4页Ji Ma Ruiqi Pu Qinyang Zhou Maoru Li Jing Shang 
This work was supported by the grants from the Major Scientific and Technological Project of the Yunnan Province Science and Technology Department(No.202002 AA100004);the Strategy for Development and Utilization of Huize Traditional Chinese Medicine Resources Program of the Chinese Academy of Engineering.
Stroke is the second leading cause of death worldwide.There are more than 2 million new stroke patients in China every year,and ischemic strokes account for 60%-70%of these patients[1].Even with proper hospital treatm...
关键词:DEATH consequences NEURAL 
花特征对一种雄先熟植物同株异花自交和繁殖成功的影响
《Journal of Plant Ecology》2023年第5期73-85,共13页Meng Hou Zhi-Gang Zhao 
the National Key Research and Development Program of China(2017YFC0504801);the National Natural Science Foundation of China(31370402,31570229,31870411)to Z.-G.Z.and(32201316)to M.H.
通过调节传粉者行为,花显示大小和花序内的花蜜梯度可以改变雄先熟植物同株异花自交的发生,进而影响植物繁殖成功。然而,对此进行验证的研究仍然较少。本研究通过测定自交率、结子数和果实内包含的雄性父本的数量,研究了花显示大小和花...
关键词:同株异花自交 雄先熟 花蜜梯度 花显示 种子数量 雄性父本数目 露蕊乌头(Aconitum gymnandrum) 
Multi-omics analysis reveals the evolutionary origin of diterpenoid alkaloid biosynthesis pathways in Aconitum被引量:3
《Journal of Integrative Plant Biology》2023年第10期2320-2335,共16页Dake Zhao Ya Zhang Huanxing Ren Yana Shi Ding Dong Zonghang Li Guanghong Cui Yong Shen Zongmin Mou Edward JKennelly Luqi Huang Jue Ruan Suiyun Chen Diqiu Yu Yupeng Cun 
supported by funding from the CAS “Pioneer Hundred Talents” Program and Strategic Priority Research Program of the Chinese Academy of Sciences (XDB31000000) to Y.C.;National Natural Science Foundation of China (Nos. 31960082, 32270395, and 31960096);Yunnan Fundamental Research Projects (No. 202101AS070021) to D.Z。
Diterpenoid alkaloids(DAs) have been often utilized in clinical practice due to their analgesic and anti-infammatory properties. Natural DAs are prevalent in the family Ranunculaceae, notably in the Aconitum genus. Ne...
关键词:Aconitum vilmorinianum acute toxicity biosynthetic pathway diterpenoid alkaloid evolutionary origin genome assembly 
Study on hepatotoxicity of Aconitum brachypodum based on network pharmacology and molecular docking
《Toxicology Advances》2022年第4期16-23,共8页Teng-Da Li An-Lan Zhao Rui Gong Xue-Feng Li Cheng Chen Xin-Ju Li 
Objective:To explore the potential mechanism of hepatotoxicity induced by Aconitum brachypodum through network toxicology.Methods:The active components and targets of Aconitum brachypodum were identified and screened ...
关键词:network pharmacology Aconitum brachypodum HEPATOTOXICITY APOPTOSIS inflammatory response oxidative stress 
Male-biased sex allocation in late-blooming flowers driven by resource limitation in the clonal perennial Aconitum kusnezoffii (Ranunculaceae)被引量:1
《Journal of Systematics and Evolution》2022年第6期1393-1404,共12页Xing-Yue M.Ge Han-Shu Lu Hao Tian Yue Wu Da-Yong Zhang Wan-Jin Liao 
This work was supported by the National Natural Science Foundation of China(No.31770253);the 111 project(No.B13008);the Beiing Advanced Innovation Program for Land Surface Science.
Flowering phenology and clonal growth are known to affect resource and pollen availability, and therefore select for adaptive or constrained sex allocation strategies to some degree. However, the consequences of tempo...
关键词:female reproductive success flowering phenology inflorescence architecture pollen limitation resource limitation sex allocation 
In vitro Germination and Micropropagation of Aconitum vilmorinianum:An Important Medicinal Plant in China
《Phyton-International Journal of Experimental Botany》2022年第10期2331-2348,共18页Zongmin Mou Fei Ye Fangchen Shen Dake Zhao 
Yunnan Fundamental Research Projects(Nos.202101AS070021,202101AT070265);the National Natural Science Foundation of China(Grant Nos.31960082,32160249);the Scientific Research Fund Project of Yunnan Education Department(No.2021J0002).
Aconitum vilmorinianum,a well-known traditional Chinese herb,is recently being threatened by overexploitation and environment disturbance.This study was conducted to provide propagation methods through in vitro germin...
关键词:Aconitum vilmorinianum seed surface bacteria in vitro multiplication ORGANOGENESIS 
2D NMR-based MatchNat Dereplication Strategy Enables Explosive Discovery of Novel Diterpenoid Alkaloids被引量:1
《Chinese Journal of Chemistry》2022年第18期2169-2178,共10页Tian-Peng Yin Yi Yu Qing-Hua Liu Ming-Yue Zhou Guo-Yuan Zhu Li-Ping Bai Wei Zhang Zhi-Hong Jiang 
funded by the Science and Technology Development Fund,Macao SAR(File Nos.0023/2019/AKP,0077/2019/A2,0002/2019/APD,and 0040/2021/AGJ);the National Natural Science Foundation of China(No.31860095)。
The tribe Delphineae,comprising two genera,Aconitum L.and Delphinium L.,is the richest source of bioactive diterpenoid alkaloids(DAs),while their highly similar chemical structures create a major challenge for derepli...
关键词:NMR spectroscopy Natural products ALKALOIDS DEREPLICATION ACONITUM 
四唑染色法快速测定北乌头种子生活力被引量:1
《湖北农业科学》2022年第15期150-152,共3页隋昕 于营 鲁海坤 于芸泽 郭靖 姜业成 
吉林省科技发展计划项目(20180201034YY);中国农业科学院科技创新工程(CAAS-ASTIP-2016-ISAPS);吉林省中药材种子种苗检测实验室项目(2018-S-44)。
为实现北乌头(Aconitum kusnezoffii)种子活力快速测定,通过4因素3水平正交试验,探究了四唑染色法(TTC)测定北乌头种子活力中各因素对染色效果的影响,并确定了最适染色条件。结果表明,在各因素对种子染色效果的影响中,染色时间>TTC浓度...
关键词:北乌头(Aconitum kusnezoffii) 种子 TTC染色法 生活力 
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