supported by the CACMS Innovation Fund(Grant Nos.:CI2021A05206,and CI2021A04504);the National Natural Science Foundation of China(Grant No.:82104380);the Fundamental Research Funds for the Central Public Welfare Research Institutes(Grant No.:ZZ14-YQ-047);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(Grant Nos.:CI2023E002,and CI2023C039YGL).
Accurate analysis of the key substances in traditional Chinese medicines(TCMs)is the prerequisite and foundation for the quality evaluation and pharmacological substance research of TCMs[1].However,the extremely compl...
supported by grants provided by the National Natural Science Foundation of China (81873090);funding from the Research on Identification and Support Innovation and Development of Enterprise Technology Projects in Hubei Province (2021BLB174);the Modern Transmission and Innovation Research Team of Traditional Chinese Medicine at South Central Minzu University
Objective: The objective of the study was to explore the potential signaling mechanism of Aconitum tanguticum(Maxim.) Stapf(ATS) and its impact on intestinal fibrosis in vitro. Methods: Network pharmacology was used t...
This work was supported by the grants from the Major Scientific and Technological Project of the Yunnan Province Science and Technology Department(No.202002 AA100004);the Strategy for Development and Utilization of Huize Traditional Chinese Medicine Resources Program of the Chinese Academy of Engineering.
Stroke is the second leading cause of death worldwide.There are more than 2 million new stroke patients in China every year,and ischemic strokes account for 60%-70%of these patients[1].Even with proper hospital treatm...
the National Key Research and Development Program of China(2017YFC0504801);the National Natural Science Foundation of China(31370402,31570229,31870411)to Z.-G.Z.and(32201316)to M.H.
supported by funding from the CAS “Pioneer Hundred Talents” Program and Strategic Priority Research Program of the Chinese Academy of Sciences (XDB31000000) to Y.C.;National Natural Science Foundation of China (Nos. 31960082, 32270395, and 31960096);Yunnan Fundamental Research Projects (No. 202101AS070021) to D.Z。
Diterpenoid alkaloids(DAs) have been often utilized in clinical practice due to their analgesic and anti-infammatory properties. Natural DAs are prevalent in the family Ranunculaceae, notably in the Aconitum genus. Ne...
Objective:To explore the potential mechanism of hepatotoxicity induced by Aconitum brachypodum through network toxicology.Methods:The active components and targets of Aconitum brachypodum were identified and screened ...
This work was supported by the National Natural Science Foundation of China(No.31770253);the 111 project(No.B13008);the Beiing Advanced Innovation Program for Land Surface Science.
Flowering phenology and clonal growth are known to affect resource and pollen availability, and therefore select for adaptive or constrained sex allocation strategies to some degree. However, the consequences of tempo...
Yunnan Fundamental Research Projects(Nos.202101AS070021,202101AT070265);the National Natural Science Foundation of China(Grant Nos.31960082,32160249);the Scientific Research Fund Project of Yunnan Education Department(No.2021J0002).
Aconitum vilmorinianum,a well-known traditional Chinese herb,is recently being threatened by overexploitation and environment disturbance.This study was conducted to provide propagation methods through in vitro germin...
funded by the Science and Technology Development Fund,Macao SAR(File Nos.0023/2019/AKP,0077/2019/A2,0002/2019/APD,and 0040/2021/AGJ);the National Natural Science Foundation of China(No.31860095)。
The tribe Delphineae,comprising two genera,Aconitum L.and Delphinium L.,is the richest source of bioactive diterpenoid alkaloids(DAs),while their highly similar chemical structures create a major challenge for derepli...