LIMONIN

作品数：6被引量：18H指数：2
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相关领域：医药卫生更多>>
相关机构：保山学院更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Precision Medicine Research》《World Journal of Clinical Oncology》《Journal of Agricultural Science and Technology(A)》更多>>
相关基金：国家自然科学基金中国博士后科学基金更多>>
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Limonin inhibits the stemness of cancer stem-like cells derived from colorectal carcinoma cells potentially via blocking STAT3 signaling被引量：1
《World Journal of Clinical Oncology》2024年第2期317-328,共12页Wei-Feng Zhang Cheng-Wei Ruan Jun-Bo Wu Guo-Liang Wu Xiao-Gan Wang Hong-Jin Chen 
BACKGROUND Limonin is one of the most abundant active ingredients of Tetradium ruticarpum.It exerts antitumor effects on several kinds of cancer cells.However,whether limonin exerts antitumor effects on colorectal can...
关键词：LIMONIN Colorectal cancer STAT3 signaling Cancer stem-like cells STAT3 Aldehyde dehydrogenase 1 
Structure-based multi-ligand molecular modeling to predict the synergistic effects of limonin and obacunone from Simiao pill against nitric oxide synthase 3 associated with hyperuricemia
《Precision Medicine Research》2023年第3期11-15,共5页Qing-Hong Chen Xiao-Mei Chen Xiao-Hu Chen Yan-Ting You Shu-Xuan Yang Chuang-Hai Wu Mei-Lin Chen Ming-Di Li Akari Komori Yan-Yan Liu Andrew Hung Xiao-Shan Zhao Hong Li 
This work was funded by the Key Project of National Natural Science Foundation of China[grant number 81830117];Joint Funds of National Natural Science Foundation of China[grant number U22A20365];National Natural Science Foundation of China[grant numbers 8220140209,82274499];Guangdong Basic and Applied Basic Research Foundation[grant number 2021A1515110082];China Postdoctoral Science Foundation[grant number 2022M711534];Science&Technical Plan of Guangzhou,Guangdong,China[grant number 201903010069].
Hyperuricemia(HUA)mainly occurs because of purine metabolism disorders.We recently proposed that limonin from Simiao pill may have therapeutic effects on nitric oxide synthase 3(NOS3)that is related to HUA.Concurrentl...
关键词：HYPERURICEMIA synergistic mechanism Chinese herbal medicine complementary and alternative medicine molecular docking molecular dynamics simulations in silico analysis 
Extraction, identification, and antioxidant property evaluation of limonin from pummelo seeds被引量：12
《Animal Nutrition》2018年第3期281-287,共7页Si Qin Chenghao Lv Qingshan Wang Zhibing Zheng Xi Sun Minyi Tang Fangming Deng 
partially supported by Natural Science Foundation of China(31101268);Core Research Program 1515 of Hunan Agricultural University of China to Si Qin
Limonin, the main bioactive phytochemical constituent of limonoids with multi-functions, is enriched in citrus fruits and often found at a high concentration in citrus seeds. The present study was attempted to introdu...
关键词：LIMONIN EXTRACTION IDENTIFICATION Nrf2-ARE pathway ANTIOXIDANT 
Discovery of novel limonin derivatives as potent anti-inflammatory and analgesic agents被引量：3
《Chinese Journal of Natural Medicines》2018年第3期231-240,共10页WANG Shao-Chi YANG Yun LIU Jing JIANG Ai-Dou CHU Zhao-Xing CHEN Si-Ying GONG Guo-Qing HE Guang-Wei XU Yun-Gen ZHU Qi-Hua 
supported by the National Natural Science Foundation of China(Grant No.21472242);the National Science and Technology Major Project for "Significant New Drugs Creation" of China(Grant No.2015ZX09102001);State Key Laboratory of Natural Medicines,China Pharmaceutical University(No.SKLNMZZCX201406)
Novel series of limonin derivatives （V-A-I-V-A-8, V-B-I-V-B-8） were synthesized by adding various tertiary amines onto the C （7）-position of limonin. The synthesized compounds possessed favorable physicochemical p...
关键词：Limonin derivatives ANALGESIC ANTI-INFLAMMATORY 
Establishment of Debittering Technique in Concentrated Orange Juice被引量：1
《Agricultural Science & Technology》2014年第2期300-303,共4页徐国良 秦云 
[Objective]To explore the debittering technique for concentrated orange juice. [Method] Active carbon was used to debitterze naringin and limonin from con-centrated orange juice. [Result] Through single-factor experim...
关键词：Concentrated orange juice DEBITTERING Active carbon NARINGIN LIMONIN 
Determination of Hesperidin and Limonin Levels as Part of the Defense Mechanism of Some Lemon Varieties [Citrus limon （L,） Burm f.] against Mal Secco Disease [Phoma tracheiphila （Petri） Kanc,et Ghik,]被引量：1
《Journal of Agricultural Science and Technology(A)》2011年第2X期149-155,共7页K. Baydar N. K. Koc E. Kafkas 
In this paper, it was aimed to identified and quantified hesperidin and limonin compounds using HPLC （High Performance Liquid Chromatography） techniques against to developing of mal secco disease caused by Phoma tra...
关键词：HPLC Phoma tracheiphila Citrus limon HESPERIDIN limonin. 
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