BACKGROUND This study describes the efficacy of a tacrolimus treatment regimen used to treat two patients with relapsing-remitting chronic inflammatory demyelinating polyradiculoneuropathy(CIDP).CASE SUMMARY Two patie...
Supported by the Fund for BeijingScience&Technology Development of TCM:the Study on the Curative Effect and Mechanism of Modification of Bushenyisui Capsules against Multiple Sclerosis with Depression Based on Magnetic Resonance Multimodal Analysis(No.JJ2018-49);the Effect of Bushenyisui Capsules on Cognitive Impairment in Patients with Relapsing and Multiple Sclerosis(No.QN2014-17);To Explore the Mechanism of Bushenyisui Capsule in Reconstituting NMOSD Immune Balance Based on the Regulation of p38 MAPK Pathway by TAK1(No.QN2018-30);Capital Medical University Scientific Research Cultivation Fund:Rl Promotes the Recovery of Neurological Function in Rats with Cerebral Hemorrhage through the Pathway of Microglial Cells Polarizing Different Neurons to Mediate the Neuroinflammatory Reaction after Cerebral Hemorrhage(No.PYZ2018142);to Explore the Mechanism of Bushenyisui Capsule Promoting Myelin Sheath Regeneration in EAE Mice by Regulating Proliferation,Differentiation and Migration of OPC by Treg Derived Nov(No.PYZ2018141);National Natural Science Foundation of China:to Explore the Mechanism of Catalpol Mediated Proliferation,Migration and Axonal Remyelination of OPC by CCN3 through the Synergetic Regulation of Cdc42 Signaling Pathway by GEFs and mir-148b-3p(No.81973599);the Study on the Mechanism of Regulating the Axon Myelination through NF and NRG1(No.81473640)。
OBJECTIVE:To investigate the changes of subcortical gray matter volume and cortical thickness,andexplorethe correlations between regional abnormalities of cortical thickness and cognitive impairment and the effect of ...
This paper reviews evidence that the presence of mast cells in specific sites of central nervous system, suggesting inflammatory processes, may explain all the symptoms observed in multiple sclerosis. This hypothesis ...
Mast cells are present in high numbers in the border-zones of the multiple sclerosis-plaques. They are located in small clusters along capillaries and venules, and they are more abundant in females than in men. Mast c...