Β1-ADRENOCEPTOR

作品数：3被引量：15H指数：3
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相关领域：医药卫生更多>>
相关期刊：《Acta Pharmacologica Sinica》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金：国家自然科学基金更多>>
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Endoplasmic reticulum stress contributed to β1-adrenoceptor autoantibody-induced reduction of autophagy in cardiomyocytes被引量：3
《Acta Biochimica et Biophysica Sinica》2019年第10期1016-1025,共10页Li Wang Na Ning Changtu Wang Xiaohong Hou Yuan Yuan Yanan Ren Cong Sun Zi Yan Xiaohui Wang Huirong Liu 
supported by the grants from the National Natural Science Foundation of China(Nos.31871177 and 31401006);Scientific and Technological Innovation Program of Higher Education Institutions in Shanxi Province(No.201802059);the Graduate Educational Innovation Project of Shanxi Province(No.2018129).
Autophagy reduction has been confirm ed as an im portant mechanism in apoptosis induction.Our previous study showed that decreased autophagy induced by Pi-adrenoceptor autoantibodies(Pi-AAs)enhanced cardiom yocyte apo...
关键词：ADRENERGIC RECEPTOR AUTOANTIBODY endoplasmic reticulum stress AUTOPHAGY apoptosis 
Autoantibody against Cardiac β_1-Adrenoceptor Induces Apoptosis in Cultured Neonatal Rat Cardiomyocytes被引量：6
《Acta Biochimica et Biophysica Sinica》2006年第7期443-449,共7页Yan GAO Hui-Rong LIU Rong-Rui ZHAO Jian-Ming ZHI 
To clarify whether apoptosis is involved in the injury processes induced by autoantibody against cardiac β1-adrenoceptor, we investigated the biological and apoptotic effects of antibodies on cultured neonatal rat ca...
关键词：Β1-ADRENOCEPTOR rat cardiomyocyte AUTOANTIBODY APOPTOSIS 
Distributive characteristics of Ser49Gly and Gly389Arg genetic polymor-phisms of β_1-adrenoceptor in Chinese Han and Dai populations被引量：6
《Acta Pharmacologica Sinica》2006年第2期254-258,共5页Zhao-qian LIU Jie LIU Zhi-hua XIANG Min-yu HU Wei MO Lian-sheng WANG Dong-sheng OU-YANG Nan HE Dan WANG Hong-hao ZHOU 
Project supported by the National Natural Science Foundation of China(№30070880);the Sponsorship for Outstanding Teachers Program,Ministry of Education,China(№2002-350).
Aim： Genetic polymorphisms causing Ser49Gly and Gly389Arg mutants of β1-adrenoceptor may result in significant changes in the function of this receptor. The aim of the present study was to investigate the frequencie...
关键词：Β1-ADRENOCEPTOR genetic polymorphism Ser49Gly Gly389Arg 
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