N-ETHYLMALEIMIDE

作品数：4被引量：9H指数：2
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相关领域：医药卫生更多>>
相关作者：刘瑾玲陆艳王玮金邦荃更多>>
相关机构：南京师范大学更多>>
相关期刊：《南京师大学报（自然科学版）》《Neural Regeneration Research》《Acta Pharmaceutica Sinica B》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划江苏省“六大人才高峰”高层次人才项目更多>>
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The critical role of the endolysosomal system in cerebral ischemia被引量：3
《Neural Regeneration Research》2023年第5期983-990,共8页Hui-Yi Zhang Ye Tian Han-Yan Shi Ya Cai Ying Xu 
supported the National Natural Science Foundation of China,No. 81970760 (to YT);the Natural Science Foundation of Liaoning Province,No. 2021-MS-201 (to YX);the 345 Talent Project of Shengjing Hospital of China Medical University,No. M0370 (to YT);the 345 Talent Project of Shengjing Hospital of China Medical University,No. M0395 (to YX)。
Cerebral ischemia is a serious disease that triggers sequential pathological mechanisms, leading to significant morbidity and mortality. Although most studies to date have typically focused on the lysosome, a single o...
关键词：AUTOPHAGY biodegradation brain injury chaperone-mediated autophagy endolysosomal system fusion HYPOXIA-ISCHEMIA brain mitophagy N-ethylmaleimide-sensitive protein TMEM175 
Rhodojaponin Ⅵ indirectly targets Cav2.2 channels via N-ethylmaleimide-sensitive fusion protein to alleviate neuropathic pain被引量：3
《Acta Pharmaceutica Sinica B》2023年第3期1326-1336,共11页Keliang Chen Tao Wang Yong Li Jun Wu Cheng-Xiao Zhao Sheng Liu Fengrun Sun Yehong Fang Jiahuan Hu Jinping Hu Chong-Jing Zhang Haibo Yu Chao Ma Shi-Shan Yu 
The Natural Science Foundation of China (Nos.21732008,and 81771205);CAMS Innovation Fund for Medical Sciences (CIFMS,Nos.CIFMS-2022-I2M-JB-009,China);The National Postdoctoral Program for Innovative Talents (No.BX20180053,China)
Neuropathic pain is a chronic disease that severely afflicts the life and emotional status of patients,but currently available treatments are often ineffective.Novel therapeutic targets for the alleviation of neuropat...
关键词：Natural product Rhodojaponin VI Neuropathic pain NSF Cav2.2 
Identification of Differentially Expressed Proteins and Validation of the Changes of N-Ethylmaleimide-sensitive Factor in Rats with Focal Cerebral Ischemia after Transection of the Cervical Sympathetic Trunk被引量：2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第6期801-807,共7页曲瑶 马克宁 李兴志 
Stellate ganglion blockade （SGB） protects patients from focal cerebral ischemic injury, and transection of the cervical sympathetic trunk （TCST） in a rat model can mimic SGB in humans. The purpose of this study wa...
关键词：middle cerebral artery occlusion stellate ganglion blockade transection of the cervicalsympathetic trunk N-ethylmaleimide-sensitive factor cerebral injury 
胞外高铁肌红蛋白还原酶电子传递活性位点的研究被引量：1
《南京师大学报（自然科学版）》2009年第4期59-64,共6页王玮 金邦荃 陆艳 刘瑾玲 
国家"863"科技攻关项目(2002AA242031-5);江苏省六大人才高峰项目(184080H10202);南京师范大学研究生优秀学位论文培育计划项目(181200000226)资助项目
以NADH为反应体系的启动剂,研究猪心肌提取液中高铁肌红蛋白还原酶(MetMbase)活性的表达,实验结果证实酶活性的表达依赖NADH启动,且0.2 mM NADH浓度可充分启动MetMbase活性的表达.研究还表明,ATP可全程抑制MetMbase呼吸链电子的传递,抑...
关键词：高铁肌红蛋白还原酶 电子传递 NADH NAN3 N-ETHYLMALEIMIDE 二价金属离子 
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