AMYGDALIN

作品数：10被引量：56H指数：4
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相关领域：医药卫生更多>>
相关作者：王雪松陈钰更多>>
相关机构：北京大学吉林大学大连理工大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《World Journal of Gastroenterology》《Asian Pacific Journal of Tropical Biomedicine》《Journal of Traditional Chinese Medicine》更多>>
相关基金：国家自然科学基金上海市青年科技启明星计划北京市自然科学基金更多>>
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Amygdalin Ameliorates Liver Fibrosis through Inhibiting Activation of TGF-β/Smad Signaling被引量：10
《Chinese Journal of Integrative Medicine》2023年第4期316-324,共9页XIAO Zhun JI Qiang FU Ya-dong GAO Si-qi HU Yong-hong LIU Wei CHEN Gao-feng MU Yong-ping CHEN Jia-mei LIU Ping 
Supported by National Natural Science Foundation of China(Nos.81530101,81973613 and 81603681);Shanghai Rising-Star Program(No.19QA1408900)。
Objective:To observe the effect of amygdalin on liver fibrosis in a liver fibrosis mouse model,and the underlying mechanisms were partly dissected in vivo and in vitro.Methods:Thirty-two male mice were randomly divide...
关键词：AMYGDALIN liver fibrosis hepatic stellate cells liver sinusoidal endothelial cells TGF-β/Smad signalingpathway 
Amygdalin attenuates PM2.5-induced human umbilical vein endothelial cell injury via the TLR4/NF-κB and Bcl-2/Bax signaling pathways被引量：2
《Acta Biochimica et Biophysica Sinica》2022年第10期1476-1485,共10页Bixu Wang Tong Sun Ling Sun Lan Li Haitong Wan Zhishan Ding Xiaoqing Ye 
supported by the grants from the National Key Research and Development Program of China(No.2019YFC1708604);Zhejiang Provincial Natural Science of Foundation of China(No.LQ20B070005);the National Natural Science Foundation of China(No.22106143);Zhejiang Provincial Fund for Outstanding Young Talents of Traditional Chinese Medicine(No.2020ZQ013).
Mounting evidence supports that long-term exposure to fine particle pollutants(PM2.5)is closely implicated in cardiovascular diseases,especially atherosclerosis.Amygdalin is reported to attenuate external stimuli-indu...
关键词：AMYGDALIN PM2.5 INFLAMMATION oxidative stress APOPTOSIS 
Evaluation of the chemical profile from four germplasms sources of Pruni Semen using UHPLC-LTQ-Orbitrap-MS and multivariate analyses被引量：3
《Journal of Pharmaceutical Analysis》2022年第5期733-742,共10页Zihan Zhao Yue Liu Yushi Zhang Zeyu Geng Rina Su Lipeng Zhou Chao Han Zhanjun Wang Shuangcheng Ma Weidong Li 
sponsored by the Key Research and Development Programs in the Ningxia Hui Autonomous Region,China(Grant No.:2020BBF02027);Beijing Natural Science Foundation(Grant No.:5212014).
Pruni Semen,the seed of several unique Prunus plants,is a traditional purgative herbal material.To determine the authentic sources of Pruni Semen,46 samples from four species were collected and analyzed.Ten compounds ...
关键词：Pruni semen Acetyl flavonoids AMYGDALIN Multivariate analyses Authentic sources 
Combined effect of microwave and hydrothermal treatment on anti-nutritional factors,antioxidant potential and bioactive compounds of plum(Prunus domestica L.)kernels被引量：2
《Food Bioscience》2022年第2期300-307,共8页Mohd Aaqib Sheikh Charanjiv Singh Saini 
This research was funded by the Indian Council of Medical Research(ICMR),Ministry of Health and Family Welfare,Government of India under the project(IRIS No.2019-5058).The authors express their profound gratitude and sincere appreciation to the ICMR for financial support to this study.
The effect of microwave heating(450 W for 6 min),hydrothermal treatment(45℃ for 6,9,12 h)and their combination on antioxidant potential,anti-nutritional factors,and phenolic compounds of plum kernels were studied.Amy...
关键词：MICROWAVE Plum kernels AMYGDALIN Hydrocyanic acid Bioactive compounds 
Chinese Medicine Amygdalin and β-Glucosidase Combined with Antibody Enzymatic Prodrug System As A Feasible Antitumor Therapy被引量：8
《Chinese Journal of Integrative Medicine》2018年第3期237-240,共4页LI Yun-long LI Qiao-xing LIU Rui-jiang SHEN Xiang-qian 
Amarogentin is an efficacious Chinese herbal medicine and a component of the bitter apricot kernel.It is commonly used as an expectorant and supplementary anti-cancer drug.β-Glucosidase is an enzyme that hydrolyzes t...
关键词：amarogentin β-glucosidase antibody enzymatic prodrug targeting therapy Chinese medicine 
Correlation between the transdermal characteristics of pseudoephedrine and amygdalin in majiepingchuan in vitro
《Journal of Traditional Chinese Medicine》2016年第2期238-242,共5页Kong Hui Qu Huihua Qu Baoping Zeng Wenhao Zhao Yan Wang Xueqian Wang Qingguo 
Supported by the Science and Technology Major Projects for Major New Drugs(Research on innovation of Majiepingchuan effective components cataplasm of transdermal drug delivery system),No.2012ZX09103201-007
OBJECTIVE: To analyze the transdermal profile of pseudoephedrine and amygdalin in the Traditional Chinese Medicine majiepingchuan in rat skin and to reveal their interaction.METHODS: A Franz diffusion cell was used in...
关键词：PSEUDOEPHEDRINE AMYGDALIN Ma jiepingchuan Transdermal flux CORRELATION 
Comparative assessment of physicochemical properties of unripe peach(Prunus persica) and Japanese apricot(Prunus mume)被引量：5
《Asian Pacific Journal of Tropical Biomedicine》2014年第2期97-103,共7页Hye-Ryun Kim II-Doo Kim Sanjeev Kumar Dhungana Mi-Ok Kim Dong-Hyun Shin 
Supported by Kyungpook National University Research Fund,2012;partly supported by Grants(2012-03)from R&D project to overcome FTA,Free Trade Agreement program 2012 in the agriculture and fishery fields of Gyeongsangbuk-Do province,Korea
Objective:To investigate the physicochemical properties of unripe peach-Pruuns persica cv.Mibaekdo(Mibaekdo) and Prunus persica cv.Nagasawa Hakuho(Nagasawa Hakuho) as an alternative to fowl supplement while Japanese a...
关键词：AMYGDALIN JAPANESE apricot(Backaha) PHYSICOCHEMICAL properties Unripe peach(Mibaekdo Nagasawa Hakuho) 
Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cells被引量：25
《World Journal of Gastroenterology》2005年第33期5156-5161,共6页Hae-Jeong Park Seo-Hyun Yoon Long-Shan Han Long-Tai Zheng Kyung-Hee Jung Yoon-Kyung Uhm Je-Hyun Lee Ji-Seon Jeong Woo-Sang Joo Sung-Vin Yim Joo-Ho Chung Seon-Pyo Hong 
Supported by a grant of the Oriental Medicine R&D Project, Ministry of Health Welfare, Republic of Korea, No. 03-PJ9-PG3-21600-0014 and No. 0405-OMOO-0815-0001 Korea Institute of Oriental Medicine
AIM： The genes were divided into seven categories according to biological function; apoptosis-related, immune response-related, signal transduction-related, cell cyclerelated, cell growth-related, stress response-rel...
关键词：AMYGDALIN SNU-C4 cDNA microarray Cell cycle 
Effect of Amygdalin on the Proliferation of Hyperoxia-exposed Type Ⅱ Alveolar Epithelial Cells Isolated from Premature Rat被引量：3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第3期223-225,共3页祝华平 常立文 李文斌 刘汉楚 
Summary: The pathogenesis of hyperoxia lung injury and the mechanism of amygdalin on type 2 alveolar epithelial cells (AEC2) isolated from premature rat lungs in vitro were investigated. AEC2 were obtained by primary ...
关键词：HYPEROXIA AMYGDALIN Type 2 alveolar epithelial cell cell proliferation 
Effect of Semen Persicae Extract Combined with Cultured Cordyceps on Reversing Capillarization of Sinusoids In Patients with Hepato-Cirrhosis
《Chinese Journal of Integrative Medicine》1997年第3期203-205,共3页徐列明 朱剑亮 刘成 刘平 吕刚 薛惠明 明义杨 洪嘉禾 
Objective: To evaluate the effect of Semen Persicae combined with cultured Cordyceps on Reversing Capillarization of Sinusoids in patients with hepato-cirrhosis. Methods: Forty-four patients were treated for 3 months...
关键词：Semen Persicae Cordyceps sinensis AMYGDALIN hepato-cirrhosis capillarization of sinusoids 
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