OSSEOINTEGRATION

作品数：120被引量：337H指数：10
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相关领域：医药卫生更多>>
相关作者：龚树生李永新郑雅丽张强谢畅更多>>
相关机构：首都医科大学南方医科大学第三附属医院温州医科大学重庆医科大学更多>>
相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《Science China(Life Sciences)》《Regenerative Biomaterials》《Transactions of Nonferrous Metals Society of China》更多>>
相关基金：国家自然科学基金中国博士后科学基金重庆市自然科学基金国家教育部博士点基金更多>>
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Cobalt ions-derived nanoenzyme array for endosseous neural network reconstruction and osseointegration
《Bioactive Materials》2024年第12期1-17,共17页Xinmei Cai Meng Yu Bo Li Yingang Zhang Yong Han 
the National Key Research and Development Program of China(Grant No.2023YFC2412600);National Natural Science Foundation of China(Grant No.51971171).
Interactions between bone cells and neurocytes are crucial for endosseous nerve and ensuing bone regeneration.However,absence of neural stem cells in bone makes the innervation of implant osseointegration a major chal...
关键词：Cobalt ions-derived nanoenzyme Neurogenic factors Mesenchymal stem cells Neural differentiation Neurovascularized osseointegration 
Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects:Reconstruction,anti-infection,and osseointegration
《Bioactive Materials》2024年第12期18-31,共14页Teng Zhang Wenhao Zhou Wanliang Yang Jingwei Bi Hao Li Xianlei Gao Baoliang Zhang Guidong Shi Ka Li Zhijian Wei Xin Pan Shiqing Feng 
supported by the National Natural Science Foundation of China[grant number 82202729];the Natural Science Foundation of Shandong Province[grant number ZR2022QH261];the Taishan Scholar Project of Shandong Province[grant number tsqn202306355];the National Natural Science Foundation of China[grant number 32101087];the Tianjin Municipal Science and Technology Program(21JCZDJC01100).
Infected bone defect is a formidable clinical challenge.Conventional approaches to prevention and treatment for infected bone defects are unsatisfactory.The key elements of the treatment are bone defect reconstruction...
关键词：Porous Ti6Al4V implants Infected bone defects ANTI-INFECTION OSSEOINTEGRATION 
Zinc finger-inspired peptide-metal-phenolic nanointerface enhances bone-implant integration under bacterial infection microenvironment through immune modulation and osteogenesis promotion
《Bioactive Materials》2024年第11期564-576,共13页Lin Xu Jie Fang Jiezhou Pan Hexu Qi Yun Yin Yunxiang He Xueqi Gan Yifei Li Yu Li Junling Guo 
National Natural Science Foundation of China(J.F.,Grant no.32000928);Sichuan Science and Technology Program(J.F.,Grant no.2023YFS0150);National Natural Science Foundation of China(Y.L.,Grant no.82270249);National Key R&D Program of China(J.G.,Grant No.2022YFA0912800);National Natural Science Foundation of China(J.G.,Grant No.22178233);National Excellent Young Scientist Fund(J.G.,Grant No.00308054A1045);Sichuan Tianfu Emei Project(J.G.,Grant No.2022-EC02-00073-CG);Talents Program of Sichuan Province(J.G.);Double First Class University Plan of Sichuan University(J.G.);State Key Laboratory of Polymer Materials Engineering(J.G.,Grant No.sklpme 2020-03-01);National Natural Science Foundation of China(Y.L.,Grant no.31971247,82371003).
Orthopedic and dental implantations under bacterial infection microenvironment face significant challenges in achieving high-quality bone-implant integration. Designing implant coatings that incorporate both immune de...
关键词：Metal-phenolic network IMPLANT OSSEOINTEGRATION Inflammation Abaloparatide 
A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implant被引量：2
《Bioactive Materials》2024年第11期336-354,共19页Yulu Yang Xianhui Zhang Yao Yang Pengfei Gao Wuzhe Fan Tao Zheng Weihu Yang Yu Tang Kaiyong Cai 
State Key Project of Research and Development(2022YFB3804400);National Natural Science Foundation of China(32071334,52333011&51825302);Natural Science Foundation of Chongqing(cstc2021jcyj-cxttX0002 and CSTB2023NSCQ-MSX0074);Visiting Scholar Foundation of Key Laboratory of Biorheological Science and Technology(Chongqing University);Ministry of Education(CQKLBST-2023-001).
Postmenopausal osteoporosis(PMOP)is a prevalent condition among elderly women.After menopause,women exhibit decreased iron excretion,which is prone to osteoporosis.To design a specific titanium implant for PMOP,we fir...
关键词：Postmenopausal osteoporosis Iron overload Ferroptosis Caffeic acid nanosphere Ti implant 
Two decades of continuous progresses and breakthroughs in the field of bioactive ceramics and glasses driven by CICECO-hub scientists
《Bioactive Materials》2024年第10期104-147,共44页H.R.Fernandes S.Kannan M.Alam G.E.Stan A.C.Popa R.Buczy′nski P.Gołębiewski J.M.F.Ferreira 
the project No.2021/43/P/ST7/02418 cofunded by the National Science Centre and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 945339;JMFF,RB,PG gratefully acknowledge the financial support provided by the Polish National Science Centre for the POLONEZ BIS 1“BAGBONE”,Project no.536651.JMFF would like to thank all the national and international research collaborators for their valuable contributions,especially for the papers covered in this review article;the scope of the project CICECOAveiro Institute of Materials,UIDB/50011/2020,UIDP/50011/2020&LA/P/0006/2020,financed by national funds through the FCT/MCTES(PIDDAC);the Department of Health Research–Indian Council of Medical Research[DHR-ICMR];India[Reference:R.11013/28/2021-GIA/HR dated November 25,2021]is recognized by SK and MA.GES and ACP are thankful to the Core Program of the National Institute of Materials Physics within the National Research Development and Innovation Plan 2022–2027,carried out with the support of the Romanian Ministry of Research,Innovation and Digitalization under the project PC2-PN23080101.
Over the past two decades, the CICECO-hub scientists have devoted substantial efforts to advancing bioactiveinorganic materials based on calcium phosphates and alkali-free bioactive glasses. A key focus has been thede...
关键词：CaP bioceramics Alkali-free bioactive glasses Bio-functional doping/substitution OSSEOINTEGRATION Antimicrobial efficiency 
Conformationally regulated“nanozyme-like”cerium oxide with multiple free radical scavenging activities for osteoimmunology modulation and vascularized osseointegration被引量：2
《Bioactive Materials》2024年第4期64-79,共16页Shusen Bao Dongmei Yu Zhen Tang Hao Wu Hao Zhang Ning Wang Yichao Liu Hai Huang Chaozong Liu Xiaokang Li Zheng Guo 
supported by grants from the National Key Research and Development Program of China(grant number 2017YFC1104900);the National Natural Science Foundation of China(No.82372124,51871239,and 51771227);the support from the Incubation Program of China Army Medical Science and Technology Youth Training Program(No.17QNP021);the Everest Program of Air Force Military Medical University(No.2020ZFC002)。
Given post-operative aseptic loosening in orthopedic disease treatment,osteointegration occurs at the bone-implant interface as a holistic process,including immunoregulation(e.g.,macrophage polarization),angiogenesis ...
关键词：“Nanozyme-like”cerium oxide Durable redox activation Free radical scavenging Osteoimmunology modulation Vascularized osseointegration 
High temperature oxidation treated 3D printed anatomical WE43 alloy scaffolds for repairing periarticular bone defects:In vitro and in vivo studies被引量：2
《Bioactive Materials》2024年第2期177-189,共13页Bingchuan Liu Jinge Liu Chaoxin Wang Zhengguang Wang Shuyuan Min Caimei Wang Yufeng Zheng Peng Wen Yun Tian 
funded by the National Key Research and Development Program of China(No.2018YFE0104200);National Natural Science Foundation of China(51875310,52175274,82172065);Peking University Medicine Sailing Program for Young Scholars’Scientific&Technological Innovation(BMU2023YFJHPY015).
Reconstruction of subarticular bone defects is an intractable challenge in orthopedics.The simultaneous repair of cancellous defects,fractures,and cartilage damage is an ideal surgical outcome.3D printed porous anatom...
关键词：Periarticular bone defects 3D printing technology Magnesium alloy High temperature oxidation OSSEOINTEGRATION 
Silver-integrated EDM processing of TiAl6V4 implant material has antibacterial capacity while optimizing osseointegration
《Bioactive Materials》2024年第1期497-508,共12页Hilmar Büssemaker Ann-Kathrin Meinshausen Viet Duc Bui Joachim Döring Vadym Voropai Adrian Buchholz Andreas J.Mueller Karsten Harnisch André Martin Thomas Berger Andreas Schubert Jessica Bertrand 
Periprosthetic joint infections(PJI)are a common reason for orthopedic revision surgeries.It has been shown that the silver surface modification of a titanium alloy(Ti-6Al-4V)by PMEDM(powder mixed electrical discharge...
关键词：alloy SILVER powder 
Enhanced osseointegration of drug eluting nanotubular dental implants: An in vitro and in vivo study
《Bioactive Materials》2023年第10期432-447,共16页Pankaj Chauhan Alok Srivastava Pooja Bhati Manish Chaturvedi Vinay Patil Sriram Kunnoth Nisha Kumari Vedpal Arya Madhur Pandya Mohit Agarwal Smiti Bhardwaj Farrukh Faraz Sanjay Chauhan Mahesh Verma Veena Koul Naresh Bhatnagar 
Faster and predictable osseointegration is crucial for the success of dental implants, especially in patients with compromised local or systemic conditions. Despite various surface modifications on the commercially av...
关键词：Titanium BIOCOMPATIBILITY SIMVASTATIN NANOTUBE Micro CT HISTOPATHOLOGY Nanoscale 
Multifunctionalized carbon-fiber-reinforced polyetheretherketone implant for rapid osseointegration under infected environment被引量：5
《Bioactive Materials》2023年第6期236-250,共15页Xiao Wang Lisha Pan Ao Zheng Lingyan Cao Jin Wen Tingshu Su Xiangkai Zhang Qingfeng Huang Xinquan Jiang 
funded by the National Natural Science Foundation of China(No.81921002,No.82100963,No.81873709);the Natural Science Foundation of Shanghai Science and Technology Commission(21ZR1437100);Shanghai Rising-Star Program(21QA1405400).
Carbon fiber reinforced polyetheretherketone(CFRPEEK)possesses a similar elastic modulus to that of human cortical bone and is considered as a promising candidate to replace metallic implants.However,the bioinertness ...
关键词：POLYETHERETHERKETONE NANOPORES Osteogenic activity VASCULARIZATION Antibacterial activity 
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