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supported by the National Institutes of Health(CA235749)。
The Hedgehog(Hh)signaling is one of the essential signaling pathways during embryogenesis and in adults.Hh signal transduction relies on primary cilium,a specialized cell surface organelle viewed as the hub of cell si...
the special fundations of Ministry of Education of China and National Natural Science Foundation of China (Grant No. 30225017)
Compared to other subcellular organelles, centrosome proteome can hardly be studied, due to the dif- ficulties in separation and purification of centrosome. Auto-antisera from 6 autoimmune patients, which recognized c...
This work was supported by the Special Funds for Major State Basic Research Project (Grant No. G1999055901)
Centrins are members of the centrosome protein family, which is highly conserved during revolution. The homologous genes of centrin in many organisms had been cloned, but the sequences of the rat centrin genes were no...