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Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice
《Asian Pacific Journal of Tropical Biomedicine》2024年第5期199-206,共8页Lucelina S.Araújo Bruno B.Silva Eduarda N.F.N.Santos Arnaldo S.Bezerra Samuel S.Frota Assis R.Montenegro Eridan O.P.T.Florean Maurício Fvan Tilburg Maria Izabel F.Guedes 
supported by grants from the Brazilian Agencies:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior(CAPES-Financial code 001);Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq);Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico(FUNCAP).
Objective:To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum,and a purified antigen.Methods:Mice were subjected to the following treatmen...
关键词：Visceral leishmaniasis K39 Inactivated bacterial vector Vaccine Immune response Th1 TH2 Leishmania infantum 
Effect of dietary supplement of inactivated Lactobacillus plantarum Ep-M 17 on growth performance,immune response,disease resistance,and intestinal microbiota in Penaeus vannamei
《Journal of Oceanology and Limnology》2024年第2期676-694,共19页Ting WU Xiaoman HU Wenlong XU Yang DU Jiong CHEN 
Supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY23D060002);the Key Scientific and Technological Grant of Zhejiang for Breeding New Agricultural Varieties(No.2021C02069-5);the Pingyang County Science and Technology Strengthening Agriculture Industry Upgrading Project(No.2023PY003);the National Natural Science Foundation of China(No.41906107)。
Our previous study found that feeding with Lactobacillus plantarum Ep-M17 could effectively affect the growth performance,immune response,and gut microbiota of Penaeus vannamei.However,high temperature and pressure du...
关键词：Penaeus vannamei Lactobacillus plantarum Ep-M17 inactivated probiotics immune response gut flora 
Inactivated SARS-CoV-2 booster vaccine enhanced immune responses in patients with chronic liver diseases
《Virologica Sinica》2023年第5期723-734,共12页Yongmei Liu Jianhua Lu Haoting Zhan Wenfang Yuan Xiaomeng Li Haiyan Kang Haolong Li Yongliang Chen Linlin Cheng Xingli Sun Haojie Zheng Wei Wang Erhei Dai Yongzhe Li 
This work was supported by the Beijing Natural Science Foundation(M23008);the National Key Research and Development Program of China(2018YFE0207300);Beijing Municipal Science&Technology Commission(Z211100002521021);the National High Level Hospital Clinical Research Funding(2022-PUMCH-B-124);Key Research and Development Plan of Hebei Province,Special Health Innovation Project(22377744D).
Chronic liver disease(CLD)entails elevated risk of COVID-19 severity and mortality.The effectiveness of the booster dose of inactivated SARS-CoV-2 vaccine in stimulating antibody response in CLD patients is unclear.Th...
关键词：Chronic liver disease(CLD) SARS-CoV-2 inactivated vaccines Booster vaccination Antibody response Immune response 
Weakened humoral and cellular immune response to the inactivated COVID-19 vaccines in Chinese individuals with obesity/overweight被引量：1
《Genes & Diseases》2023年第2期608-617,共10页Qian Zhu Yingzhi Zhang Juan Kang Zhiwei Chen Mingli Peng Min Chen Gaoli Zhang Dejuan Xiang Shuang Xiao Hu Li Ying Mei Jie Yang Xiaoya Qi Dachuan Cai Hong Ren 
supported by the National Science and Technology Major Project of China(No.2017ZX10202203-007,No.2017ZX10202203-008,and No.2018ZX10302206-003);a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No.81772198);the Natural Science Foundation of Chongqing,China(No.cstc2020jcyj-msxmX0389);General Project of Chongqing Natural Science Foundation(No.cstc2020jcyj-msxmX0015).
Inactivated COVID-19 vaccines have been widely used to vaccinate the Chinese population.However,limited literature exists to explore the effect of obesity on the humoral and cellular immune response to these vaccines....
关键词：COVID-19 Immune response Inactivated vaccine OBESITY OVERWEIGHT 
Inactivated Pseudomonas PE(△Ⅲ)exotoxin fused to neutralizing epitopes of PEDV S proteins produces a specific immune response in mice被引量：2
《Animal Diseases》2021年第3期205-211,共7页Leqiang Sun Yajie Tang Keji Yan Huanchun Chen Huawei Zhang 
This research was funded by the National Natural Science Foundation of China(31900746 and 31802170);Postdoctoral Science Foundation(2019M660182).
Porcine epidemic diarrhea(PED)caused by the porcine epidemic diarrhea virus(PEDV),is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.An increased...
关键词：Porcine epidemic diarrhea virus S protein Neutralizing antibody Th1-type immune response 
Exposure to heat-inactivated Trichophyton rubrum resulting in a limited immune response of human keratinocytes被引量：2
《Chinese Medical Journal》2013年第2期215-219,共5页HUANG Xiao-qiang YI Jin-ling YINSong-chao CHEN Rong-zhang LI Mei-rong GONG Ziojian LAI Wei CHEN Jian 
This Work was supported by the grants from theFundamental Research Funds for the Central Universities （No. 10ykpy04） and the National Natural Science Foundation of China （No. 30600028）.
Background Trichophyton rubrum （T. rubrum） represents the most important agent of dermatophytosis in humans. T. rubrum infection causes slight inflammation, and tends to be chronic and recurrent. It is suggested tha...
关键词：human keratinocytes Trichophyton rubrum  pattern recognition receptors  immune response 
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