supported by the National Key Research and Development Program of China(2022YFC2604100,2022YFC2302900,2021YFC2301400,and 2022YFE0131700);National Natural Science Foundation of China(92169208,32222031,82071813,32141004,and 82171775);Peking University People’s Hospital Research and Development Funds(RDGS2022-05);National Postdoctoral Program for Innovative Talents of China(BX20220332)。
Studies have focused on neutralizing antibody titers and T-cell activation induced by vaccination against different SARS-CoV-2strains[1,2].Advanced single-cell technology has allowed for a comprehensive evaluation of ...
supported by Guangzhou Laboratory,Grant Award Number:EKPG21-30-4.
The safety and efficacy of COVID-19 vaccines in the elderly,a high-risk group for severe COVID-19 infection,have not been fully understood.To clarify these issues,this prospective study followed up 157 elderly and 73 ...
Background We explored the influence of diabetes on the antibody levels of elderly individuals after inoculation with an inactivated vaccine against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and the f...
supported by the National Science and Technology Major Project of China(Nos 2017ZX10202203-007,2017ZX10202203-008,2018ZX10302206-003)and a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No 81772198);Natural Science Foundation of Chongqing,China(No.cstc2020jcyjmsxmX0389).
Background and Aims:SARS-CoV-2 vaccines-associated autoimmune liver diseases have been reported in several case reports.However,the safety and immunogenicity after primary and booster inactivated SARS-CoV-2 vaccinatio...
This work was supported by the Beijing Natural Science Foundation(M23008);the National Key Research and Development Program of China(2018YFE0207300);Beijing Municipal Science&Technology Commission(Z211100002521021);the National High Level Hospital Clinical Research Funding(2022-PUMCH-B-124);Key Research and Development Plan of Hebei Province,Special Health Innovation Project(22377744D).
Chronic liver disease(CLD)entails elevated risk of COVID-19 severity and mortality.The effectiveness of the booster dose of inactivated SARS-CoV-2 vaccine in stimulating antibody response in CLD patients is unclear.Th...
Key R&D Program of Guangdong Province(No.2021A1111110002);Guangzhou Basic Research Program on People’s Livelihood Science and Technology(No.202002020005);National Natural Science Foundation of China(No.82072265)
To the Editor:Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the virus that caused the 2019 coronavirus disease(COVID-19)pandemic.Over two years after the initial outbreak,several more infectious variat...
the grants from Hangzhou Global Scientific and Technological Innovation Center of Zhejiang University(KC2021ZY0B0003).
The contamination of Atlantic salmon with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has impeded the development of the cold-chain food industry and posed possible risks to the population.Electron beam...
supported by the National Science and Technology Major Project of China(2017ZX10202203-007,2017 ZX10202203-008,2018ZX10302206-003);Remarkable Innovation-Clinical Research Project,The Second Affiliated Hospital of Chongqing Medical University and The First batch of key Disciplines On Public Health in Chongqing;support of the National Natural Science Foundation of China(81772198);Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0389).
Background and Aims:Our aim was to determine the immune efficacy of a severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)booster vaccination in cirrhotic patients who had received the primary series.Methods:We...
The COVID-19 pandemic has led to unprecedented levels of morbidity,mortality,and economic disruption worldwide.Several non-pharmaceutical interventions have been implemented worldwide to curb the spread of SARS-CoV-2,...