MUTAGENICITY

作品数:97被引量:42H指数:4
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相关领域:医药卫生更多>>
相关作者:王玉荣周安祥王子元林磊光王秀玲更多>>
相关机构:白银公司劳动卫生研究所哈尔滨医科大学中国科学院上海医科大学更多>>
相关期刊:《Journal of Cosmetics, Dermatological Sciences and Applications》《Science China Chemistry》《World Journal of Gastroenterology》《Journal of Pharmacy and Pharmacology》更多>>
相关基金:国家自然科学基金更多>>
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Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review
《Journal of Pharmaceutical Analysis》2024年第5期639-652,共14页Hemanth P.R.Vikram Tegginamath Pramod Kumar Gunjan Kumar Narasimha M.Beeraka Rajashree Deka Sheik Mohammed Suhail Sandeep Jat Namitha Bannimath Gayatiri Padmanabhan Ravandur S.Chandan Pramod Kumar Bannimath Gurupadayya 
The presence of N-nitroso compounds,particularly N-nitrosamines,in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.This systematic review investigates...
关键词:CARCINOGENICITY GENOTOXICITY MUTAGENICITY Molecular toxicity Nitrosamine impurities Nitrosamine drug substance-related IMPURITIES 
In vitro cytotoxic and toxicological activities of ethanolic extract of Kaempferia galanga Linn. and its active component,ethyl-p-methoxycinnamate, against cholangiocarcinoma被引量:1
《Journal of Integrative Medicine》2020年第4期326-333,共8页Porwornwisit Tritripmongkol Tullayakorn Plengsuriyakarn Mayuri Tarasuk Kesara Na-Bangchang 
funded by Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma of Thammasat University;Thammasat University Research fund under the TU Research Scholar(Contract No.03/2561)。
Objective:To evaluate the cytotoxic,apoptotic,mutagenic and immunomodulatory activities of Kaempferia galanga Linn.(KG)extract and ethyl-p-methoxycinnamate(EPMC)in vitro.Methods:The present study investigated the cyto...
关键词:Kaempferia galanga Linn. Cytotoxicity CHOLANGIOCARCINOMA MUTAGENICITY Apoptosis Immunomodulatory activity 
Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process
《Biomedical and Environmental Sciences》2018年第8期632-636,共5页FANG Dao Kui ZHOU Guo Hong YU Shu Yuan FENG Jin Shu 
supported by grants from Science and Technology Planning Project of Shenzhen [No.200703079]
Purification of surface water is widely practiced with conventional water treatment processes like coagulation-flocculation, sedimentation, filtration,and disinfection. Some reports have specified that conventional wa...
关键词:Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process 
Mutagenicity of Wastewater Extracts from Pulp and Paper Industry
《Journal of Environmental Protection》2017年第2期206-213,共8页Samira Umme Aiman Abdul Malik 
Wastewater samples were collected from pulp and paper mill located in Kashipur (India) and were extracted using dichloromethane (DCM), chloroform and hexane solvents (all were HPLC-grade). The extracts were assayed fo...
关键词:MUTAGENICITY PULP and PAPER Industry WASTEWATER EXTRACTS 
Examination of in vivo mutagenicity of sodium arsenite and dimethylarsinic acid in gpt delta rats被引量:1
《Journal of Environmental Sciences》2016年第11期125-130,共6页Masaki Fujioka Min Gi Satoko Kawachi Kumiko Tatsumi Naomi Ishii Kenichiro Doi Anna Kakehashi Hideki Wanibuchi 
supported by a Grant from the Food Safety Commission, Cabinet Office, Japan (Research Program for Risk Assessment Study on Food Safety, No. 1407)
Arsenic is a well-known human bladder and liver carcinogen, but its exact mechanism of carcinogenicity is not fully understood. Dimethylarsinic acid(DMAV) is a major urinary metabolite of sodium arsenite(i As~Ⅲ) ...
关键词:Dimethylarsinic acid Sodium arsenite In vivo mutagenicity Urinary bladder epithelium gpt delta rat 
Development of QSAR Model for Predicting the Mutagenicity of Aromatic Compounds被引量:1
《Chinese Journal of Structural Chemistry》2015年第3期324-334,共11页刘阳华 周志祥 张晓龙 李捍东 
Supported by the Ministry of Environmental Protection of China(No.2011467037)
Quantitative structure-activity relationship (QSAR) model was developed for pre- dicting the mutagenicity of aromatic compounds. The log revertants data of S. typhimurium TA98 strain from Ames test have been collect...
关键词:aromatic compounds quantitative structure-activity relationship (QSAR) MULTIPLE 
Is the Photosuturing Agent, Rose Bengal, a Mutagen?
《Journal of Cosmetics, Dermatological Sciences and Applications》2014年第1期24-30,共7页Lindsey Hunter-Ellul Shuguang Wang Jeffrey Wickliffe Michael Wilkerson 
Rose Bengal (RB) is a potential photosuturing agent that may improve standard dermatologic surgical closure techniques. However, RB produces reactive oxygen species with photoactivation and its photomutagenic potentia...
关键词:ROSE BENGAL PHOTOCHEMICAL Tissue Bonding MUTAGENICITY Cytotoxicity Wound HEALING Dermatological Surgery 
Screening for Genotoxicity and Oestrogenicity of Endocrine Disrupting Chemicals <i>in Vitro</i>
《Journal of Environmental Protection》2012年第8期902-914,共13页Karthryn M. Quinn-Hosey James J. Roche Andrew M. Fogarty Concepta A. Brougham 
A diverse range of endocrine disrupting chemicals (EDCs) was examined, using an in vitro test system, for critical events required for the onset of carcinogenesis in vivo. The initiation stage of carcinogenesis is a g...
关键词:Four Endocrine Disrupting Chemicals (EDCs) Proliferation MUTAGENICITY DNA Strand Breakage Comet ASSAY DNA Repair Unscheduled DNA Synthesis ASSAY (UDS) E-SCREEN ASSAY YES ASSAY MVLN ASSAY 
Influence of Temperature on Mutagenicity in Plants Exposed to Surface Disinfected Drinking Water
《Journal of Water Resource and Protection》2012年第8期638-647,共10页Bianca Gustavino Elisabetta Ceretti Claudia Zani Ilaria Zerbini Marco Rizzoni Silvano Monarca Donatella Feretti 
Disinfection of surface drinking water, particularly water chlorination, produces by-products with potential genotoxic and/or carcinogenic activity. A study carried out at a pilot plant for drinking water disinfection...
关键词:Clastogenicity/Aneugenicity Allium cepa Aberration TEST VICIA faba MICRONUCLEUS TEST TEMPERATURE Exposure Water Disinfection 
Preliminary Study by Environmental Indicator Measurements of Sediments in a Mangrove Forest in Ilha Grande Bay,Rio de Janeiro,Southeastern Brazil
《Journal of Environmental Protection》2012年第8期731-739,共9页Ana Maria A.Velho Claudia A.F.Aiub Jose L.Mazzei Sergio M.Correa Mario L.G.Soares Israel Felzenszwalb 
the Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro(FAPERJ),Coordination for the improvement of Higher Education Personnel(Capes)and National Council of Technological and Scientific Development(CNPq)for fellowships and financial support.
Mangroves perform essential functions in biological cycles and are protected by law in Brazil. However, they are being degraded above their support limit, leading to a reduction in the areas around the world. The area...
关键词:SEDIMENTS MUTAGENICITY Goniopsis cruentata GENOTOXICITY Polycyclic Aromatic Hydrocarbons(PAHs) Metals 
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