ENDOTOXIN

作品数：255被引量：1096H指数：16
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相关作者：李兰娟马伟杭吴仲文陈亚岗俞云松更多>>
相关机构：浙江大学医学院附属第一医院复旦大学南京大学大连医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金高等学校学科创新引智计划更多>>
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Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment被引量：1
《Current Medical Science》2022年第1期26-38,共13页Min XU Li-li LUO Meng-yi DU Lu TANG Jie ZHOU Yu HU Heng MEI 
This study was supported by grants from the National Natural Science Foundation of China(No.81873434)and the Natural Science Foundation of Hubei Province(No.2020CFA065).
Objective:The systemic inflammatory response is regarded as the major cause of endotoxin-induced coagulopathy,which is a strong predictor of mortality in patients with severe sepsis.Simvastatin plays an important role...
关键词：ENDOTOXEMIA endotoxin-induced coagulopathy SIMVASTATIN inflammatory cytokines intestinal permeability intestinal microorganism 
FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation被引量：8
《World Journal of Gastroenterology》2014年第39期14430-14441,共12页Jun Yao Chun-Suo Zhou Xiong Ma Bai-Qing Fu Li-Sheng Tao Miao Chen Ya-Ping Xu 
AIM: To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism.
关键词：Farnesoid X receptor Nonalcoholic fatty liver disease GW4064 Nonalcoholic fatty liver disease activity score Lipopolysaccharide-induced hepatic inflammation Macrophage activation 
15-deoxy-△12,14-prostaglandin J2 ameliorates endotoxin-induced acute lung injury in rats被引量：7
《Chinese Medical Journal》2014年第5期815-820,共6页Geng Zhilong Zhu Wankun Wang Huiwen Chen Ye Liang Juan Liu Dong 
Background A proinflammatory milieu emerging in the lung due to neutrophil accumulation and activation is a key in the pathogenesis of acute lung injury （ALI）.15-deoxy-△12,14-prostaglandin J2 （15d-PGJ2）,one of th...
关键词：acute lung injury ENDOTOXIN 15-deoxy-△12  14-prostaglandin J2 nuclear factor kappa B 
Effects of Hydroxyethyl Starch 130/0.4 Pretreatment on Endotoxin-InducedAcute Lung Injury in Rats
《麻醉与监护论坛》2010年第3期174-179,共6页Wei Zhang Cai Fang Jun Ma Yan-hu Xie Juan Li 
关键词：医学 麻醉 监护技术 医院 
α_1-ANTITRYPSIN ATTENUATES ENDOTOXIN-INDUCED ACUTE LUNG INJURY IN RABBITS
《Journal of Shanghai Second Medical University(Foreign Language Edition)》2003年第2期71-76,共6页揭志军 蔡映云 杨文兰 金美玲 朱威 祝慈芳 
theScientificFundfromtheMinistryofHealth(98115 0 ) ,China
Objective To investigate whether pretreatment with α 1-AT can attenuate acute lung injury (ALI) in rabbits induced with endotoxin. Methods Thirty-two New Zealand rabbits were randomly assigned to four groups(n=8):1.I...
关键词：acute lung injury    α  1-antitrypsin    neutrophil elastase    endotoxin 
In vivo expression of lipopolysaccharide binding protein and its gene induced by endotoxin被引量：1
《Chinese Journal of Traumatology》2003年第5期280-283,共4页李旭宏 龚建平 涂兵 石毓君 刘长安 
theNationalNaturalScienceFoundationofChina (No .39970 719;30 170 919)
Objective: To investigate the expression of lipopolysaccharide binding protein (LBP) and its gene in rats with endotoxemia and explore the role of LBP in the response of host to endotoxin. Methods: Thirty Wistar rats ...
关键词：ENDOTOXEMIA Kupffer cells Lipopolysaccharide binding protein 
Protective effects of α_1 -antitrypsin on acute lung injury in rabbits induced by endotoxin被引量：11
《Chinese Medical Journal》2003年第11期1678-1682,共5页揭志军 蔡映云 杨文兰 金美玲 朱威 祝慈芳 
the Scientific Foundation of the Ministry of Health (No: 98-1-150)
Objective To investigate whether pretreatment with α1,-antitrypsin (AAT) can attenuate acute lung injury (ALI) in rabbits induced with endotoxin.Methods Thirty-two healthy adult New Zealand rabbits were anaesthetized...
关键词：acute lung injury ·α1-antitrypsin neutrophil elastase ·rabbits ENDOTOXIN 
Effect of endothelin-1 on hepatic damage induced by endotoxin被引量：1
《Chinese Journal of Traumatology》2000年第4期234-237,共4页刘宝华 肖南 陈惠孙 周继红 
To observe effect of endothelin-1 (ET-1) on hepatic damage induced by endotoxin. Methods: A total of 90 rats were randomly divided into control group (group C), endotoxin treated group (group LPS) and endotoxin plus E...
关键词：内毒素 肝损伤 内皮素-1 
Immunohistochemical studies on the endotoxin-induced uveitis
《Chinese Medical Journal》1998年第3期60-64,共5页杨培增 
AbstractThe Netherlands Ophthalmic Research Institute, Amsterdam (Yang PZ, de Vos AF, and Kijlstra A). Amsterdam University, Amsterdam, The Netherlands (Kijlstra A). The project is supported by a grant from Guangdon...
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