In this editorial,we discuss the clinical implications of the article by Zhang et al.Pulmonary alveolar proteinosis(PAP)is a rare lung disease characterized by excessive surfactant accumulation in the alveoli.It is cl...
Supported by Sanitation Research Project of Kunming Municipal Health Commission,No.2020-06-01-119.
BACKGROUND Pulmonary alveolar proteinosis(PAP)and X-linked agammaglobulinemia(XLA)are rare diseases in children.Many theories infer that immunodeficiency can induce PAP,but these reports are almost all review articles...
BACKGROUND The ATP6AP1 gene coding for the accessory protein Ac45 of the vacuolar-type adenosine triphosphatases(V-ATPase)is located on chromosome Xq28.Defects in certain subunits or accessory subunits of the V-ATPase...
Supported by Natural Science Foundation of Zhejiang Province,China,No.LQ19H160019;Zhejiang Provincial Basic Public Welfare Research Project,China,No.LGF19H140006;Zhejiang TCM Science and Technology Plan,China,No.2018ZA071,and No.2019ZA069;Medical Scientific Research Foundation of Zhejiang Province,China,No.2019KY379.
BACKGROUND Trismus is a common problem with various causes.Any abnormal conditions of relevant anatomic structures that disturb the free movement of the jaw might provoke trismus.Trismus has a detrimental effect on th...
National Natural Science Foundation of China,No. 11571309;the Zhejiang Health Bureau Fund,No. 2016ZHA004。
BACKGROUND X-linked agammaglobulinemia is a primary immunodeficiency disease caused by gene mutations of Bruton’s tyrosine kinase(BTK).We found a new mutation point and summarized the correlation analysis and perform...
Supported by Chinese National Special Research Program for Important Infectious Diseases,No.2017ZX10202102-002-002;National Science and Technology Major Project,No.2018ZX10715-014-004
BACKGROUND Kaposi’s sarcoma(KS)is one of the most common cancers in human immunodeficiency virus(HIV)-positive patients and leads to a high prevalence of morbidity and mortality.It usually appears as cutaneous or muc...
BACKGROUND Highly active antiretroviral therapy (HAART) is provided free of charge to all human immunodeficiency virus (HIV) positive residents in Italy. As fixed dose coformulations (FDCs) are often more expensive in...
Supported by the National Natural Science Foundation of China,No.81301016;the Beijing Municipal Administration of Hospitals Incubating Program,No.PX2019009
BACKGROUND Syphilitic myelitis caused by Treponema pallidum is an extremely rare disease. However, symptomatic neurosyphilis, especially syphilitic myelitis, and its clinical features have been infrequently reported. ...
A 54-year-old black African woman, 22 years human immunodeficiency virus(HIV)-positive, presented with an acute coronary syndrome. She was taking two nucleoside reverse transcriptase inhibitors and two protease inhibi...
AIM: To review all cases of abdominal tuberculosis(ATB) for demographic details, diagnostic work up and evidence of vitamin D deficiency.METHODS: This was a retrospective analysis of all patients diagnosed with ATB fr...