云南高校图书馆联盟文献共享服务平台- SARCOMA

SARCOMA: 作品数：333被引量：548H指数：11; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陆维祺田蕾张勤刘贵秋张传山更多>>; 相关机构：复旦大学复旦大学附属肿瘤医院天津市第三中心医院苏州大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金甘肃省科技攻关计划更多>>

Deciphering the molecular interplay and tumorigenesis in hepatocellular carcinoma through insights into FBXL6 and KRAS^(G12D): 《Military Medical Research》2025年第3期464-466,共3页Qiang Cai Quazi T.H.Shubhra; supported by the National Natural Science Foundation of China(82271518,81971158,and 81671306);the Interdisciplinary Innovative Talents Foundation from Renmin Hospital of Wuhan University(JCRCFZ-2022-030);the Guiding Projects of Traditional Chinese Medicine in 2023–2024 by Hubei Provincial Administration of Traditional Chinese Medicine(ZY2023F038).; Liver cancer,particularly hepatocellular carcinoma,remains a formidable challenge in medical research and requires a deeper understanding of its molecular underpinnings.In a fascinating recent study published in Milit...; 关键词：Hepatocellular carcinoma F-box and leucine-rich repeat 6(FBXL6)activation Kirsten rat sarcoma(KRAS)^(G12D)mutation Mitogen-activated protein kinase(MEK)/mammalian target of rapamycin(mTOR)pathway Metastasis

Novel surgical approach-cadaveric inferior vena cava graft reconstruction following leiomyosarcoma resection:A case report: 《World Journal of Gastrointestinal Surgery》2025年第2期285-290,共6页Hadeel A AlOmran Bayan AlMatar Mohammed AlMonsained Shoukat Bojal Hammam Momani Mohammed S AlQahtani; BACKGROUND Inferior vena cava(IVC)leiomyosarcomas are rare and aggressive tumors.Complete cure depends on achieving R0 resection,which often requires circumferential resection and reconstruction.Synthetic grafts have ...; 关键词：Inferior vena cava leiomyosarcoma Vascular sarcoma Vascular reconstruction Venous cadaveric graft Case report

Pancreatic primitive neuroectodermal tumors:Clinical features,treatment,and influencing factors: 《World Journal of Gastrointestinal Oncology》2025年第2期230-245,共16页Yan-Fei He Huan-Zhi Wang Xiao-Dong Hu Jun-Qiang Liu Hu-Ming Li Jie Wang Shuang-Feng Lu; BACKGROUND Data on clinical characteristics,treatment outcomes,and prognosis of pancreatic primitive neuroectodermal tumors(PNETs)are limited.AIM To analyze the clinical data of 30 patients with pancreatic PNETs to id...; 关键词：Primitive neuroectodermal tumor PANCREAS SARCOMA DIAGNOSIS PROGNOSIS TREATMENT

Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions:A case report: 《World Journal of Clinical Cases》2025年第2期39-49,共11页Seungmee Lee Yu-Ra Jeon Changmin Shin Sun-Young Kwon Sojin Shin; Supported by Grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute,funded by the Ministry of Health&Welfare,Republic of Korea,No.RS-2022-KH129889.; BACKGROUND The classification of uterine sarcomas is based on distinctive morphological and immunophenotypic characteristics,increasingly supported by molecular genetic diagnostics.Data on neurotrophic tyrosine recept...; 关键词：Uterine sarcoma Cervical sarcoma Neurotrophic tyrosine receptor kinase gene fusion Next generation sequencing Case report

Classic Low-Grade Fibromyxoid Sarcoma: A Case Report and Literature Review: 《Journal of Biosciences and Medicines》2025年第1期1-12,共12页Jinglin He Xuecheng Ge Changzheng Shi; Background: The low-grade fibromyxoid sarcoma (LGFMS) is an exceptionally uncommon sarcoma that primarily manifests in the extremities or trunk of young adults, presenting as painless lesions. The histological feature...; 关键词：Low-Grade Fibromyxoid Sarcoma Rare Sarcoma Case Report

Comprehensive Bioinformatics Analysis Reveals Kirsten Rat Sarcoma Virus Oncogene(KRAS)as the Potential Biomarker of Esophageal Carcinoma: 《Proceedings of Anticancer Research》2024年第6期209-222,共14页Muhammad Akram; In the current study, the expression of the Kirsten rat sarcoma virus oncogene (KRAS) in esophageal carcinoma (ESCA) was examined for its medical and therapeutic relevance. ESCA has a 20% five-year survival rate, plac...; 关键词：KRAS ESCA Therapeutic BIOMARKER Bioinformatics

Breast Phyllodes Sarcoma in a 12-Year-Old Girl: A Case Report: 《Open Journal of Obstetrics and Gynecology》2024年第12期1821-1826,共6页Saki Corneille Téa Dia Jean Marc Lamine Okon Gérard Traoré Ibrahim Guié Privat; Introduction Phyllodes sarcomas are rare malignant tumors of childhood and adolescence. Objective: To analyze the epidemiological, diagnostic and therapeutic management of this pathology, highlighting its challenges i...; 关键词：Phyllodesarcoma PEDIATRICS MASTECTOMY

Elevated FBXL6 activates both wild-type KRAS and mutant KRAS^(G12D)and drives HCC tumorigenesis via the ERK/mTOR/PRELID2/ROS axis in mice: 《Military Medical Research》2024年第6期818-838,共21页Hao-Jun Xiong Hong-Qiang Yu Jie Zhang Lei Fang Di Wu Xiao-Tong Lin Chuan-Ming Xie; supported by the National Natural Science Foundation of China(82370631);the Talent Foundations from Army Medical University(4174C6),the Chongqing Government(CQYC20220303727)to Xie CM;the National Natural Science Foundation of China(31900449)to Xiong HJ.; Background:Kirsten rat sarcoma(KRAS)and mutant KRAS^(G12D)have been implicated in human cancers,but it remains unclear whether their activation requires ubiquitination.This study aimed to investigate whether and how F...; 关键词：UBIQUITINATION Kirsten rat sarcoma(KRAS) F-box and leucine-rich repeat 6(FBXL6) PRELID2 Reactive oxygen species Extracellular signal-regulated kinase(ERK) Mammalian target of rapamycin

Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development: 《Oncology Research》2024年第12期1837-1850,共14页WEITAO ZHENG DONG JIANG SONGEN CHEN MEILING WU BAOQI YAN JIAHUI ZHAI YUNQIANG SHI BIN XIE XINGWANG XIE KANGHONG HU WENXUE MA; funded by the key R&D Project of Hubei Province(Social Development),China(2022BCA018);the Cooperative Innovation Center of Industrial Fermentation(Ministry of Education&Hubei Province),China(2022KF16)to Kanghong Hu.; Objectives:The Kirsten rat sarcoma virus(KRAS)G12D oncogenic mutation poses a signiﬁcant challenge in treating solid tumors due to the lack of speciﬁc and effective therapeutic interventions.This study aims to explore...; 关键词：T cell receptor(TCR) TCR therapy Tumor-infiltrating lymphocytes(TILs) Kirsten rat sarcoma virus(KRAS) G12D Alloreactivity

Solitary fibrous tumor:A case report of this multifaceted tumor: 《World Journal of Clinical Cases》2024年第25期5791-5797,共7页Hani Maalouf Ribal Aby Hadeer Souad Ghattas Omar Tabbikha Hasan Numan Raja Wakim; BACKGROUND Solitary fibrous tumor(SFT)is a remarkably uncommon mesenchymal tumor.STAT6 level and a combination of clinical,pathological,and molecular features are required to arrive at a proper diagnosis.CASE SUMMARY ...; 关键词：Solitary fibrous tumor Retroperitoneal tumor Soft tissue neoplasms SARCOMA NAB2-STAT6 Case report

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