supported by the National Natural Science Foundation of China(31972883 and 32270620 to C.H.H.,31930057 to F.W.,31970757 to P.F.X.,82000155 to Y.M.);the Key Program of Natural Science Foundation of Zhejiang Province(LZ23C060001 to C.H.H.);the National Key Research and Development Program of China(2021YFC2700903 and2022YFC2704203 to C.H.H.);the National Key Research and Development Program of China(2018YFA0507802 to F.W.,2018YFA0800102 to F.H.,2021YFC2700403 to J.M.);the China Postdoctoral Science Foundation(2021M702877 to Y.M.)。
N6-methyladenosine(m^(6)A)is a critical regulator in the fate of RNA,but whether and how m^(6)A executes its functions in different tissues remains largely obscure.Here we report downregulation of a crucial m^(6)A rea...
supported by grants from the National Natural Science Key Foundation of China(Grant No.82030092).
Objective: Hypoxia is an important feature of pancreatic ductal adenocarcinoma(PDAC). Previously, we found that hypoxia promotes ENO1 expression and PDAC invasion. However, the underlying molecular mechanism was remai...
利用MCI gel CHP-20、ODS、Sephadex LH-20、硅胶及半制备高效液相等多种色谱技术,从皂角刺乙酸乙酯部位分离得到7个木脂素类化合物,并根据波谱数据分析鉴定其结构,分别为(7R,8S,7'E,7''S,8''R)-buddlenol P(1)、(+)-丁香脂素(2)、(+)-...
Tetrahydrocurcumin(THC)is one of the major metabolites of curcumin(CUR),an ancient bioactive natural polyphenolic compound.This research article describes both the solid and liquid state characterization of THC using ...
Curcumin is a medicinal agent that exhibits anti-cancer properties and bioactive pigment in Turmeric has a huge thera-peutic value.It has a keto-enol moiety that gives rise to many of its chemical properties.A recent ...
Supported by the African Union(African Union;No.17/2014)
Objective: To bioprospect optimal phenological phases as source of novel molecules from native golden yellow Pleurotus citrinopileatus across four phenologies in both aqueous and ethanol extracts, and identify novel m...
Opuntia joconostle fruit is a rich source of biocompounds such as polyphenols including gallic, vanilic, 4-hidroxybenzoic, cafeic, and syringic acids, catechin, epicatechin, rutin, and vanillin, besides betalains. The...
The spermicidal activity of 5 phenol aldehydes compounds in vitro was compared in various species including rats, mice, rabbits, hamsters, dogs and human. In rats, mice,