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作品数:54被引量:86H指数:6
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相关领域:理学更多>>
相关作者:刘刚齐曼冯卫生翟俊宜林元华更多>>
相关机构:吉林农业大学清华大学河南中医药大学中国农业科学院更多>>
相关期刊:《Chinese Journal of Structural Chemistry》《Science Bulletin》《南开大学学报(自然科学版)》《Journal of Biomaterials and Nanobiotechnology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金高等学校学科创新引智计划更多>>
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YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths被引量:2
《National Science Review》2023年第12期77-91,共15页Jiebo Lin Guankai Zhan Jinfeng Liu Yasen Maimaitiyiming Zhiping Deng Baohua Li Kunhui Su Jiafeng Chen Siqi Sun Wanlin Zheng Xianghui Yu Feng He Xiaodong Cheng Lingfang Wang Bin Shen Ziqin Yao Xinquan Yang Jian Zhang Wentao He Hengyu Wu Hua Naranmandura Kao-Jung Chang Junxia Min Jun Ma Mikael Björklund Peng-Fei Xu Fudi Wang Chih-Hung Hsu 
supported by the National Natural Science Foundation of China(31972883 and 32270620 to C.H.H.,31930057 to F.W.,31970757 to P.F.X.,82000155 to Y.M.);the Key Program of Natural Science Foundation of Zhejiang Province(LZ23C060001 to C.H.H.);the National Key Research and Development Program of China(2021YFC2700903 and2022YFC2704203 to C.H.H.);the National Key Research and Development Program of China(2018YFA0507802 to F.W.,2018YFA0800102 to F.H.,2021YFC2700403 to J.M.);the China Postdoctoral Science Foundation(2021M702877 to Y.M.)。
N6-methyladenosine(m^(6)A)is a critical regulator in the fate of RNA,but whether and how m^(6)A executes its functions in different tissues remains largely obscure.Here we report downregulation of a crucial m^(6)A rea...
关键词:RNA m^(6)A modification programmed cell deaths bifurcation role of YTHDF2 environmental stress and m^(6)A regulation fluorene-9-bisphenol(BHPF) 
ENO1 expression and Erk phosphorylation in PDAC and their effects on tumor cell apoptosis in a hypoxic microenvironment被引量:2
《Cancer Biology & Medicine》2022年第11期1598-1616,共19页Huizhi Sun Jing Mo Runfen Cheng Fan Li Yue Li Yuhong Guo Yanlei Li Yanhui Zhang Xiaoyu Bai Yalei Wang Xueyi Dong Danfang Zhang Jihui Hao 
supported by grants from the National Natural Science Key Foundation of China(Grant No.82030092).
Objective: Hypoxia is an important feature of pancreatic ductal adenocarcinoma(PDAC). Previously, we found that hypoxia promotes ENO1 expression and PDAC invasion. However, the underlying molecular mechanism was remai...
关键词:Pancreatic cancer HYPOXIA ENOL APOPTOSIS Erk phosphorylation 
皂角刺中的一个新木脂素被引量:6
《药学学报》2020年第12期2951-2954,共4页何晨 曹彦刚 齐曼 张贝贝 任英杰 刘晏灵 王梦娜 郑晓珂 冯卫生 
中央引导地方科技重大发展专项:河南道地大宗药材种质评价及集约化种植与示范(豫财科[2016]149号).
利用MCI gel CHP-20、ODS、Sephadex LH-20、硅胶及半制备高效液相等多种色谱技术,从皂角刺乙酸乙酯部位分离得到7个木脂素类化合物,并根据波谱数据分析鉴定其结构,分别为(7R,8S,7'E,7''S,8''R)-buddlenol P(1)、(+)-丁香脂素(2)、(+)-...
关键词:皂荚属 皂角刺 木脂素类 (7R 8S 7'E 7''S 8''R)-buddlenol P 
Solid and liquid state characterization of tetrahydrocurcumin using XRPD, FT-IR, DSC, TGA, LC-MS, GC-MS, and NMR and its biological activities被引量:1
《Journal of Pharmaceutical Analysis》2020年第4期334-345,共12页Mahendra Kumar Trivedi Parthasarathi Panda Kalyan Kumar Sethi Mayank Gangwar Sambhu Charan Mondal Snehasis Jana 
Dabur Research Foundation,New Delhi,India
Tetrahydrocurcumin(THC)is one of the major metabolites of curcumin(CUR),an ancient bioactive natural polyphenolic compound.This research article describes both the solid and liquid state characterization of THC using ...
关键词:TETRAHYDROCURCUMIN Liquid chromatography-mass spectrometry Spectroscopic and thermal analysis Keto-enol tautomer ANTI-INFLAMMATORY Antioxidant 
Medicinal Plant Using Ground State Stabilization of Natural Antioxidant Curcumin by Keto-Enol Tautomerisation
《Natural Products and Bioprospecting》2018年第5期369-390,共22页S.Manimaran K.Sambath Kumar R.Gayathri K.Raja N.Rajkamal M.Venkatachalapathy G.Ravichandran C.Lourdu EdisonRaj 
Curcumin is a medicinal agent that exhibits anti-cancer properties and bioactive pigment in Turmeric has a huge thera-peutic value.It has a keto-enol moiety that gives rise to many of its chemical properties.A recent ...
关键词:CURCUMIN NMR.Uv HOMO-LUMO.MEP 
Bioprospecting optimal phenology for bioactive molecules in native golden yellow Pleurotus citrinopileatus Singer
《Asian Pacific Journal of Tropical Biomedicine》2016年第2期132-142,共11页Godfrey Nattoh Erastus Gatebe Fredrick Musieba Julius Mathara 
Supported by the African Union(African Union;No.17/2014)
Objective: To bioprospect optimal phenological phases as source of novel molecules from native golden yellow Pleurotus citrinopileatus across four phenologies in both aqueous and ethanol extracts, and identify novel m...
关键词:BIOPROSPECTING Primordial PHENOLOGY Bioactive molecules Liquid chromatography-quadrupole time of flight mass spectrometry EDIBLE fungi 
Protective Effect of Phenolic-Rich Extracts from Different Parts of <i>Opuntia joconostle</i>Fruit against Carbon Tetrachloride-Induced Oxidative Stress in Mice
《Journal of Biomaterials and Nanobiotechnology》2013年第3期35-42,共8页Obed Osorio-Esquivel Alicia Ortiz-Moreno Julieta Herrera-Martínez María Dolores Hernández-Navarro 
Opuntia joconostle fruit is a rich source of biocompounds such as polyphenols including gallic, vanilic, 4-hidroxybenzoic, cafeic, and syringic acids, catechin, epicatechin, rutin, and vanillin, besides betalains. The...
关键词:OPUNTIA joconostle Oxidative Stress Carbon TETRACHLORIDE Phenolic Compounds 
A COMPARATIVE STUDY ON THE ANTIFERTILITY EFFECT OF PHENOL ALDEHYDES COMPOUNDS
《Journal of Reproduction and Contraception》1989年第1期186-186,共1页WANGYue-E GOZhi-Ping JIANGXiu-Juan WUGuo-Pei 
The spermicidal activity of 5 phenol aldehydes compounds in vitro was compared in various species including rats, mice, rabbits, hamsters, dogs and human. In rats, mice,
关键词:乙醛 化合物 杀精剂 避孕药 
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