EPITOPES

作品数：96被引量：141H指数：7
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相关领域：医药卫生更多>>
相关作者：郭礼和费俭夏国宏邢力叶欣更多>>
相关机构：中国科学院上海生命科学研究院郑州大学南昌大学广州血液中心更多>>
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An antibody cocktail with broadened mutational resistance and effective protection against SARS-CoV-2
《Science China(Life Sciences)》2023年第1期165-179,共15页Chunyun Sun Hang Chi Fei Yuan Jing Li Ji Yang Aihua Zheng Fei Wang Lingling Sun Yanjing Zhang Ping Hu Lihua Jiao Yongqiang Deng Liangzhi Xie 
supported by the National Key Research and Development Project of China(2021YEF0201700)。
Neutralizing antibodies have been proven to be highly effective in treating mild and moderate COVID-19 patients,but continuous emergence of SARS-CoV-2 variants poses significant challenges.Antibody cocktail treatments...
关键词：SARS-CoV-2 COVID-19 EPITOPES antibody cocktail mutational escape 
SARS-CoV-2 Epitopes following Infection and Vaccination Overlap Known Neutralizing Antibody Sites被引量：1
《Research》2022年第2期71-84,共14页Li Yang Te Liang Lane M.Pierson Hongye Wang Jesse K.Fletcher Shu Wang Duran Bao Lii Zhang Zhen Huang Wenshu Zheng Xiaomei Zhang Heewon Park Yuwen Li James E.Robinson Amy K.Fechan Christopher J.Lyon Jing Cao Lisa A.Morici Chenzhong Li Chad J.Roy Xiaobo Yu Tony Hu 
supported by the Department of Defense(grant number W8IxwH19i0926);National Institute of Allergy and Infectious Diseases contract(grant number_HHSN2722017000331);National Institute of Child Health and Human Development grant(grant numbers R01HD090927 and R01HDi03511);National Center for Research Resources and the Ofice of Research Infrastructure Programs(grant numbers OD011104).
Identification of epitopes targeted following virus infection or vaccination can guide vaccine design and development of therapeutic interventions targeting functional sites,but can be laborious.Herein,we employed pep...
关键词：vaccine ANTIBODY LIKELY 
Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV被引量：5
《Cellular & Molecular Immunology》2020年第5期536-538,共3页Ming Zheng Lun Song 
by the National Natural Science Foundation of China(numbers 31570758,91743115,and 31270797)to L.S.
Recently,the World Health Organization(WHO)has declared the novel coronavirus(2019-nCoV)outbreak a Public Health Emergency of International Concern(PHEIC),1 which is now formally named as severe acute respiratory synd...
关键词：RESPIRATORY acute cases 
Anti-epitope antibody, a novel site-directed antibody against human acetylcholinesterase
《Acta Pharmacologica Sinica》2004年第4期431-435,共5页Xing-meiZHANG GangLIU Man-jiSUN 
Project supported by the "9th Five-Year" Military Medicine Health Science Foundation (No 96Z017).
AIM: To construct synthetic antigens using the epitope of human brainacetylcholinesterase (hbAChE) for induction and detection of the specific antibody against theepitope, and to analyse the immunogenicity of the anti...
关键词：ACETYLCHOLINESTERASE BUTYRYLCHOLINESTERASE EPITOPES antibodies enzyme-linked immunosorbent assay Western blotting 
Monoclonal Antibodies Against Human Brain Acetylcholinesterase and Properties of Epitopes Directed by the Antibodies
《Chinese Science Bulletin》1994年第16期1392-1397,共6页朱美财 孙曼霁 辛颜彬 方允中 
Project supported by the National Natural Science Foundation of China.
Acetylcholinesterase (AChE, EC, 3, 1, 1, 7,) is distributed in human nervous system, and also in non-nervous systems such as erythrocytes and serum. It is a kind of secretory as well as membrane-combining protein. The...
关键词：human brain ACETYLCHOLINESTERASE MONOCLONAL ANTIBODY epitope. 
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