The article Epitopes for a 2019-nCoV vaccine,written by Guglielmo Lucchese,was originally published Online First without Open Access.After publication in volume 17,pages 539–540,the author decided to opt for Open Cho...
The World Health Organization has declared the rapidly spreading coronavirus to be a global pandemic.The FDA is yet to approve a vaccine for human novel coronavirus.Here,we developed a peptide-based vaccine and used h...
Coronavirus belonging to family Coronaviridae is a large group of viruses causing respiratory and gastrointestinal diseases.The outbreak of 2019-novel coronavirus has created panic in the whole world after being trans...
supported by The Drug Innovation Major Project(Grant No.2018ZX09711001);the Key Research and Development Projects of Science and Technology Department of Shandong Province(Grant No.2017CXGC1309);Shandong Provincial Natural Science Foundation of China(Grant No.ZR2019MH078,ZR2017MH086)
Conventional influenza vaccines are based on predicting the circulating viruses year by year,conferring limited effectiveness since the antigenicity of vaccine strains does not always match the circulating viruses.Thi...
Epitopes are small segmented antigenic peptides that are able to elicit the immune response by recognizing B and T-cells.In the present scenario,knowledge of immunogenic epitopes specific to severe acute respiratory s...
by a“Gerhard Domagk”research grant awarded by the University of Greifswald Medical School。
After causing an initial cluster of Pneumonia in Wuhan City,Hubei Province,the 2019-nCoV has quickly spread through South East Asia and within a few weeks to Europe,Africa,and America.Initial estimates suggested a mor...
This work was supported by a grant from the National Natural Science Foundation of China (No: 81372447).
Epstein-Barr virus (EBV) is prevalent throughout the world and is associated with several malignant diseases in humans. Latent membrane protein 2 (LMP2) of EBV plays a crucial role in the pathogenesis of EBV-assoc...
Objective Four B and Th cell epitopes were selected from conservative domain of Plasmodium falciparum antigens to construct two groups of chimeric malaria DNA vaccines with different configurations and their antigeni...
Cholera toxin B subunit is a good carrier protein and an effective adjuvant which can boost both cellular and humoral immunity. DNA fragments encoding B cell, Th cell and CTL epitopes of P. falciparum CS, MSA-1, MSA-2...