We gratefully acknowledge the National Natural Science Foundation of China(21971026 and 22171028);Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology(BM2012110)for their financial support.
A rhodium-catalyzed dearomative rearrangement reaction of 2-oxypyridines has been developed by using cyclopropenes as carbene precursors.This protocol features broad substrate scope and mild reac-tion conditions,provi...
Main observation and conclusion In this article,we report a base-promoted sequential cyclization/aldol-type condensation/isomerization cascade reaction of N-propargyl-β-enaminones with aryl aldehydes.The key step in ...
financially supported by the 100 Leading Talents of Guizhou Province (fund for W. Zhu and X. Hao);the Science and Technology Project of Guizhou (No. QKHT Z-20144007);the Academician Workstation of Guizhou (No. QKH YSZ2015-4009)
Citridones E-G (1-3), three new phenylpyridone derivatives together with two known curvularins (4 and 5) were isolated from the solid culture of the endophytic fungus Penicillium sumatrense GZWMJZ-313 in Garcinia mult...
Introduction: Pyridone derivatives played important roles in the last decade to approach many and different functionalities, especially as antitumor, antibacterial, anti-fungal, and many of pharmacological activities....
supported by the National Natural Science Foundation of China (20872106,20972107)
An efficient method was developed for the synthesis of arylidene heterobicyclic 3-cyano-2-pyridones via ytterbium chloride catalyzed tandem condensation of aromatic aldehydes,cyclic ketones,and cyanoacetamide.The cond...
A new series of 3-cyano-2-pyridones derivatives have been prepared by reaction of enaminonitriles with pri-mary amine under solvent free condition. This procedure have the advantage of high yields and being environ-me...
supported by the National Basic Research Program of China(No.2004CB518908);the National High Technology Research and Development Program of China(No.2006AA020601).
A variety of vinamidinium salts were condensated with cyanoacetamide in refluxing methanol that contained sodium methoxide to produce 5-aryl-3-cyano-2-pyridones in good yield. Simple experimental conditions were used ...
Butanons, 2-pentanone,2-hexanone and cyclohexanone were cyanoethylated,using KOH/HOCH2CH2OCH2 as a catalyst,giving yields of more than 30%.There inorganic acid salts,NaHSO4,KHSO4 and KH2PO4,were employed for the first...