ERYTHROBLAST

作品数：8被引量：4H指数：1
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相关领域：生物学医药卫生更多>>
相关作者：刘桂生陈清轩阚晟李文雍房芳更多>>
相关机构：华南生物医药研究院中国科学院遗传与发育生物学研究所军事医学科学院更多>>
相关期刊：《Science China(Life Sciences)》《Virologica Sinica》《Developmental and Reproductive Biology》《Blood Science》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Vagal-mAChR4 signaling promotes Friend virus complex(FV)-induced acute erythroleukemia
《Virologica Sinica》2023年第3期429-439,共11页Shuting Song Zhekai Lin Caiqi Zhao Jing Wen Jie Chen Shitao Xie Huaxin Qi Jianhua Wang Xiao Su 
from National Natural Science Foundation of China(82241042,81970075,81730001,91942305);National Key Research and Development Program of China(2022YFC2304700);Science and Technology Commission of Shanghai Municipality(20DZ2261200);Innovative research team of high-level local universities in Shanghai(SHSMU-ZDCX20210602).
Erythroleukemia belongs to acute myeloid leukemia(AML)type 6(M6),and treatment remains difficult due to the poor prognosis of the disease.Friend virus(FV)is a complex of two viruses:Friend murine leukemia virus(F-MuLV...
关键词：Vagus nerve Friend virus(FV) Acute erythroleukemia ERYTHROBLAST Choline acetyltransferase(ChAT) 
Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythroblasts被引量：1
《Journal of Molecular Cell Biology》2022年第2期18-31,共14页Yijin Chen Yong Dong Xulin Lu Wanjing Li Yimeng Zhang Bin Mao Xu Pan Xiaohong Li Ya Zhou Quanming An Fangxin Xie Shihui Wang Yuan Xue Xinping Cai Mowen Lai Qiongxiu Zhou Yan Yan Ruohan Fu Hong Wang Tatsutoshi Nakahata Xiuli An Lihong Shi Yonggang Zhang Feng Ma 
supported by the National Basic Research Program(973 Program,2015CB964902);the National Natural Science Foundation of China(H81170466 and H81370597);the CAMS Initiatives for Innovative Medicine(2016-I2M-1-018,2019-I2M-1-006,and 2017-I2M-2005)to F.M.,the National Natural Science Foundation of China Youth Fund(82000119)to Yonggang Zhang.
The aryl hydrocarbon receptor(AHR)plays an important role during mammalian embryo development.Inhibition of AHR signaling promotes the development of hematopoietic stem/progenitor cells.AHR also regulates the function...
关键词：ERYTHROBLAST AHR SR-1 human pluripotent stem cells DIFFERENTIATION 
Erythroid Lineage Cells in the Liver:Novel Immune Regulators and Beyond
《Journal of Clinical and Translational Hepatology》2020年第2期177-183,共7页Li Yang Kyle Lewis 
The lineage of the erythroid cell has been revisited in recent years. Instead of being classified as simply inert oxygen carriers, emerging evidence has shown that they are a tightly regulated in immune potent populat...
关键词：ERYTHROBLAST Immune suppression Liver inflammation Hepatogenesis 
Erythroblast island macrophages: recent discovery and future perspectives被引量：1
《Blood Science》2019年第1期61-64,共4页Wei Li Yaomei Wang Lixiang Chen Xiuli An 
Erythroblastic island(EBI),composed of a central macrophage surrounded by developing erythroid cells,is a structure found in hematopoietic tissues such as fetal liver and bone marrow.It is the first described hematopo...
关键词：EPOR Erythroblast islands Erythroblastic island macrophages ERYTHROPOIESIS 
Novel methods for studying normal and disordered erythropoiesis
《Science China(Life Sciences)》2015年第12期1270-1275,共6页LIU Jing HAN Xu AN XiuLi 
supported by grants from the National Natural Science Foundation of China(81470362;81171905;81272187)
Erythropoiesis is a process during which multipotential hematopoietic stem cells proliferate, differentiate and eventually form mature erythrocytes. Interestingly, unlike most cell types, an important feature of eryth...
关键词：ERYTHROPOIESIS erythroid progenitors ERYTHROBLAST surface markers transcriptional profile 
p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis被引量：2
《Cell Research》2012年第3期539-550,共12页Simon M Schultze Andreas Mairhofer Dan Li Jin Cen Hartmut Beug Erwin F Wagner Lijian Hui 
Acknowledgments We are grateful to Dr U Klingmuller （German Cancer Research Center, Germany） for providing the ErGFPcre mice; Dr J Han （Univiersity of Xiamen, China） for providing the p38ct wild-type and AF mutant plasmids; V Komnenovic （IMP, Austria） for histological analyses; and G Litos and M Kerenyi for technical support. We thank L Bakiri for critical reading of the manuscript. The IMP is funded by Boehringer Ingelheim. Work in LH laboratory is funded by the National Natural Science Foundation of China （30623003, 31071238）, Shanghai Pujiang Program （09P J1411200） and the Knowledge Innovation Program of Shanghai Institutes for Biological Sciences （2009KIP101）. Work in EFW laboratory is supported by a grant from F-BBVA and an ERC-Advanced grant ERC-FCK/2008/37.
Enucleation of erythroblasts during terminal differentiation is unique to mammals. Although erythroid enucleation has been extensively studied, only a few genes, including retinoblastoma protein （Rb）, have been iden...
关键词：p38α ENUCLEATION stress erythropoiesis Rb p38α ENUCLEATION stress erythropoiesis RB 
The Cloning of Erythropoiesis-related Genes with the Innovated Model System
《Developmental and Reproductive Biology》2002年第2期101-111,共11页阚晟 李文雍 刘桂生 陈清轩 
TheprojectwassupportedbytheNationalNaturalScienceFoundationofChina (No.3 0 0 70 42 3 7)
Most studies of erythropoiesis have been performed either with the virally transformed MEL cells or with the scarce erythroblasts within unhomogeneous cell populations.MEL cells are the Friend virus transformed mouse...
关键词：fetal sheep ERYTHROPOIESIS ERYTHROBLAST 
THE　RELATIONSHIPS　BETWEEN　ERYTHROBLAST　DENUCLEATION　AND　THE　NUCLEAR　MATRIX－INTERMEDIATE　FILAMENTS
《Chinese Medical Sciences Journal》1995年第1期1-5,共5页马文丽 薛社普 
We present a novel approach for making cybrids. By introducing neo gene expression plasmids into rabbit reticulocytes, fusing the gene transferred reticulocytes with K562 cells and selecting in G418 selection medium, ...
关键词：gene transfer cell fusion nuclear matrix-intermediate filament 
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