MACAQUE

作品数：47被引量：139H指数：6
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相关领域：医药卫生生物学更多>>
相关作者：李青青张亚平更多>>
相关机构：中国科学院中国科学院研究生院北京大学复旦大学更多>>
相关期刊：《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Virologica Sinica》《Chinese Medical Journal》更多>>
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Stability and dynamics of dendritic spines in macaque prefrontal cortex被引量：2
《National Science Review》2022年第9期140-149,共10页Ming Chen Junqian Qi Muming Poo Yang Yang 
supported by the Shanghai Municipal Science and Technology Major Project(2018SHZDZX05 and2021SHZDZX);the Shanghai Municipal Science and Technology Project(21015800100);the Strategic Priority Research Program of CAS(XDB32070100);the Key Research Program of Frontier Sciences of CAS(QYZDY-SSW-SMCO01);the International Partnership Program of CAS(153D31KYSB20170059);the Lingang Laboratory(2021050107)to M.M.P.;the Shanghai Tech Startup Fund and the National Natural Science Foundation of China(31970960)to Y.Y。
Formation and elimination of synapses reflect structural plasticity of neuronal connectivity.Here we performed high-resolution two-photon imaging of dendritic spines in the prefrontal cortex of four macaque monkeys an...
关键词：long-term two-photon imaging macaque monkey spine plasticity dendritic spine distribution regulation of spine dynamics dorsal lateral prefrontal cortex 
A single-cell transcriptome atlas of the aging human and macaque retina被引量：2
《National Science Review》2021年第4期43-60,共18页Wenyang Yi Yufeng Lu Suijuan Zhong Mei Zhang Le Sun Hao Dong Mengdi Wang Min Wei Haohuan Xie Hongqiang Qu Rongmei Peng Jing Hong Ziqin Yao Yunyun Tong Wei Wang Qiang Ma Zeyuan Liu Yuqian Ma Shouzhen Li Chonghai Yin Jianwei Liu Chao Ma Xiaoqun Wang Qian Wu Tian Xue 
supported by the National Key Research and Development Program of China(2020YFA0112200);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020601/03 and XDB39000000);the National Key Research and Development Program of China(2019YFA0110100,2017YFA0103303 and 2017YFA0102601);the National Natural Science Foundation of China(81925009,81790644,31671072,81891001,81900855,31771140 and 31900712);the Fundamental Research Funds for the Central Universities(WK2070000174and WK2090050048);the National Resource Center for NonHuman Primates and Beijing Brain Initiative of Beijing Municipal Science&Technology Commission(Z181100001518004)。
The human retina is a complex neural tissue that detects light and sends visual information to the brain.However,the molecular and cellular processes that underlie aging primate retina remain unclear.Here,we provide a...
关键词：single-cell RNA sequencing primate retina AGING cell heterogeneity age-related disease cell-cell communication 
BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders被引量：29
《National Science Review》2019年第1期87-100,共14页Peiyuan Qiu Jian Jiang Zhen Liu Yijun Cai Tao Huang Yan Wang Qiming Liu Yanhong Nie Fang Liu Jiumu Cheng Qing Li Yun-Chi Tang Mu-ming Poo Qiang Sun Hung-Chun Chang 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32060200 to H-C.C.,XDB32060100 to Q.S.and XDB32070100 to M-m.P.);Shanghai Municipal Science and Technology Major Project(2018SHZDZX05 to H-C.C.,Q.S.and M-m.P.);Shanghai Municipal Government Bureau of Science and Technology(18JC1410100 to H-C.C.,Q.S.and M-m.P.);the Ministry of Science and Technology(973Program,2011CBA00400);Hundreds of Talents Program of CAS to H-C.C.,the National Natural Science Foundation of China(31671221 to H-C.C);the Chinese Academy of Sciences(QYZDY-SSW-SMC001 to M-m.P.);the Chinese Academy of Sciences Key Technology Talent Program(to Q.S.);the National Postdoctoral Program for Innovative Talents(to Z.L.)
Circadian disruption is a risk factor for metabolic, psychiatric and age-related disorders, and non-human primate models could help to develop therapeutic treatments. Here, we report the generation of BMAL1 knockout c...
关键词：CIRCADIAN RHYTHMS BMAL1 MACAQUE monkey SLEEP disruption PSYCHOSIS aging 
Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer被引量：17
《National Science Review》2019年第1期101-108,共8页Zhen Liu Yijun Cai Zhaodi Liao Yuting Xu Yan Wang Zhanyang Wang Xiaoyu Jiang Yuzhuo Li Yong Lu Yanhong Nie Xiaotong Zhang Chunyang Li Xinyan Bian Mu-ming Poo Hung-Chun Chang Qiang Sun 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32060100 to Q.S.,XDB32060200 to H-C.C.and 32070100to M-m.P.);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX05 to Q.S.,Z.L.,H-C.C.and M-m.P.);the Shanghai Municipal Government Bureau of Science and Technology(18JC1410100 to Q.S.,H-C.C.and M-m.P.);the Ministry of Science and Technology(973 Program,2011CBA00400);the Institute of Neuroscience Director’s Fund(to M-m.P.);the National Postdoctoral Program for Innovative Talents(to Z.L.);the National Key Research and Development Program of China(2018YFC1003000 to Q.S.and Z.L.);the National Natural Science Foundation of China Grant(31825018to Q.S.)
Cloning of macaque monkeys by somatic cell nucleus transfer(SCNT) allows the generation of monkeys with uniform genetic backgrounds that are useful for the development of non-human primate models of human diseases. He...
关键词：MACAQUE monkey CLONING SOMATIC cell nuclear transfer non-human PRIMATE models CRISPR/Cas9 GENE editing CIRCADIAN rhythm disorders 
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