Funded by National Center for Gene Therapy and Drugs Based on RNA Technology MUR-CN3 CUP E63C22000940007.
Scaffold proteins are crucial regulators of signaling networks,and their abnormal expression may favor the development of tumors.Among the scaffold proteins,immunophilin covers a unique role as‘protein-philin’(Greek...
supported by the National Natural Science Foundation of China(31700206);the Natural Science Basic Research Program of Shaanxi(2016JM3023);the Special Scientific Research Project of Education Department of Shaanxi Province(16JK1792)。
In plant chloroplasts,photosystem II(PSII)complexes,together with light-harvesting complex II(LHCII),form various PSII-LHCII supercomplexes(SCs).This process likely involves immunophilins,but the underlying regulatory...
supported in part by grants from the Universidad de Buenos Aires,No.UBACYT 20020170100558BA;Agencia Nacional de Promoción Científica y Tecnológica,No.PICT 2016-0545 and PICT 2018-0546 (all to MDG)。
The term immunophilin involves a family of proteins whose domain shows peptidylprolyl-(cis/trans)-isomerase (PPIase)enzymatic activity,i.e., the reversible cis/trans interconversion of Xaa-Pro bonds (Annett et al.,202...
We thank Veder Garcia (University of California, Berkeley, USA) for critically reading the paper, Zengyong He for providing the AtFKBP53::GUS transgenic line and Masami Horikoshi (The University of Tokyo, Japan) for the pET-6His-SpFkbp39P plasmid. This work was supported by grants from the National Science Foundation and US Department of Energy (toSL).
Chromatin structure is important for controlling gene expression, but mechanisms underlying chromatin remodel- ing are not fully understood. Here we report that an FKBP (FK506 binding protein) type immunophilin, AtF...