supported by the National Natural Science Foundation of China (No.82002620,No.81972839,NO.8207112153);the Science and Technology Project of Henan Province (No.212102310698,NO.222102310102).
The CLKs(Cdc2-like kinases)belong to the dual-specificity protein kinase family and play crucial roles in regulating transcript splicing via the phosphorylation of SR proteins(SRSF1–12),catalyzing spliceosome molecul...