PHOSPHOLIPID

作品数:150被引量:241H指数:8
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相关领域:医药卫生生物学更多>>
相关作者:周华隆曲玉华王增文史东林尉志武更多>>
相关机构:有利凯玛广州代表处中山医学大学新疆阿勒泰地区人民医院武汉市中心医院更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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Transcriptional regulation of phospholipid transport in cotton fiber elongation by GhMYB30D04–GhHD1 interaction complex
《Journal of Integrative Plant Biology》2024年第11期2431-2449,共19页Qingwei Song Chuanhui Du Yiyang Xu Jin Wang Min Lin Kaijing Zuo 
funded by Biological Breeding-Major Projects(2023ZD04076);National Science Foundation of China(32370267)。
Cotton fiber length is basically determined by wellcoordinated gene expression and phosphatidylinositol phosphates(PIPs) accumulation during fiber elongation but the regulatory mechanism governing PIPs transport remai...
关键词:cotton fiber fiber cell elongation MYB–HD-ZIP transcription complex phospholipid transport transcriptional regulation 
Changes in the gene expression of activation-induced cytidine deaminase in peripheral blood mononuclear cells in COVID-19 patients
《Journal of Acute Disease》2024年第5期173-178,共6页Nioosha Ahmadi Hossein Lajmiri Saeedeh Ebrahimi Hadi Razavi Nikoo Mehrdad Farrokhnia Elham Heidari Elham Mousavi 
Objective:To assess the changes in gene expression of activation-induced cytidine deaminase(AID)in COVID-19 patients and its relationship with the presence of autoantibodies in those ones.Methods:This retrospective st...
关键词:SARS-CoV-2 Activation-induced cytidine deaminase Anti-nuclear antibody Anti-phospholipid antibody Anti-cyclic citrullinated peptide antibody 
Establishing cell suitability for high-level production of licorice triterpenoids in yeast
《Acta Pharmaceutica Sinica B》2024年第9期4134-4148,共15页Wentao Sun Shengtong Wan Chuyan Liu Ruwen Wang Haocheng Zhang Lei Qin Runming Wang Bo Lv Chun Li 
grants from the National Key Research and Development Program of China(2021YFC2100800);the National Natural Science Foundation of China(No.22108154,No.22138006,No.32171430,No.22278240);the Natural Science Foundation of Beijing Municipality(M21010,China);the Shuimu Tsinghua Scholar Program(2020SM097,China).
Yeast has been an indispensable host for synthesizing complex plant-derived naturalcompounds, yet the yields remained largely constrained. This limitation mainly arises from overlookingthe importance of cell and pathw...
关键词:Cell suitability Phospholipid microenvironment Cytochrome P450 TRITERPENOIDS Saccharomyces cerevisiae 
Probing and imaging phospholipid dynamics in live cells
《Life Metabolism》2024年第4期13-27,共15页Zhongsheng Wu Yongtao Du Tom Kirchhausen Kangmin He 
supported by the National Natural Science Foundation of China(92354305,32321004,and 91957106 to K.H.);the Ministry of Science and Technology of the People’s Republic of China(2022YFA1304500 to K.H.).
Distinct phospholipid species display specific distribution patterns across cellular membranes,which are important for their struc-tural and signaling roles and for preserving the integrity and functionality of the pl...
关键词:PHOSPHOLIPID BIOSENSOR lipid-binding domain live-cell imaging 
光响应基因BcCfaS通过脂质代谢调控灰葡萄孢菌的光形态建成及致病力
《Engineering》2024年第4期201-213,共13页Guangjin Li Zhanquan Zhang Yong Chen Tong Chen Boqiang Li Shiping Tian 
supported by the National Natural Science Foundation of China(31930086 and 32172642);the National Key Research and Development(R&D)Program of China(2016YFD0400902 and 2021YFD2100505).
Light is a fundamental environmental factor for living organisms on earth—not only as a primary energy source but also as an informational signal.In fungi,light can be used as an indicator for both time and space to ...
关键词:Light Botrytis cinerea Cyclopropane fatty-acyl-phospholipid synthase Lipid metabolism PHOTOMORPHOGENESIS Virulence 
Reducing lipid peroxidation attenuates stress-induced susceptibility to herpes simplex virus type 1被引量:1
《Acta Pharmacologica Sinica》2023年第9期1856-1866,共11页Jing-yu Weng Xin-xing Chen Xiao-hua Wang Hui-er Ye Yan-ping Wu Wan-yang Sun Lei Liang Wen-jun Duan Hiroshi Kurihara Feng Huang Xin-xin Sun Shu-hua Ou-Yang Rong-rong He Yi-fang Li 
supported by the Natural Science Foundation of Guangdong (2023B1515040016 and 2021B1515120023);the National Natural Science Foundation of China (Grant numbers 82125038,82274123 and 82174054);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (2017BT01Y036);the Innovation Team Project of Guangdong Provincial Department of Education (2020KCXTD003)and GDUPS (2019);the National Key Research and Development Program of China (2022YFC0867400).
Psychological stress increases the susceptibility to herpes simplex virus type 1(HSV-1)infection.There is no effective intervention due to the unknown pathogenesis mechanisms.In this study we explored the molecular me...
关键词:Herpes simplex virus type 1 STRESS CORTICOSTERONE arachidonate lipoxygenase 15 phospholipid peroxidation STING viral infection rosmarinicacid neuronal cells 
In Situ-Activated Phospholipid-Mimic Artemisinin Prodrug via Injectable Hydrogel Nano/Microsphere for Rheumatoid Arthritis Therapy
《Research》2023年第3期187-203,共17页Yawei Du Chao Li Yu Zhang Wei Xiong Fei Wang Juan Wang Yingze Zhang Lianfu Deng Xinsong Li Wei Chen Wenguo Cui 
the National Key Research and Development Program of China(2020YFA0908200);National Natural Science Foundation of China(91949203 and 22105127);Shanghai Municipal Health Commission(202140128);Shanghai Pujiang Program(21PJD045);Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(2019PT320001);Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(20171906);GuangCi Professorship Program of Ruijin Hospital Shanghai Jiao Tong University School of Medicine.
In situ-activated therapy is a decent option for localized diseases with improved efficacies and reduced side effects,which is heavily dependent on the local conversion or activation of bioinert components.In this wor...
关键词:activation drugs preparing 
Dynamic responses ofPAto environmental stimuli imaged by a genetically encoded mobilizable fluorescent sensor被引量:2
《Plant Communications》2023年第3期99-111,共13页Teng Li Xingkai Xiao Qingyun Liu Wenyan Li Li Li Wenhua Zhang Teun Munnik Xuemin Wang Qun Zhang 
supported by the National Key R&D Program of China(2022YFA1303400 and 2022YFD1201700);the National Natural Science Foundation of China(32270301 and 31970300);the Jiangsu Agriculture Science and Technology Innovation Fund(CX-20-2007);the Fundamental Research Funds for the Central Universities(XUEKEN2022002).
Membrane fluidity,permeability,and surface charges are controlled by phospholipid metabolism and transport.Despite the importance of phosphatidic acid(PA)as a bioactive molecule,the mechanical properties of PA translo...
关键词:PHOSPHOLIPID phosphatidic acid RbohD heat stress SALINITY abscisic acid 
Efficient secretory expression of phospholipase D for the high-yield production of phosphatidylserine and phospholipid derivates from soybean lecithin被引量:2
《Synthetic and Systems Biotechnology》2023年第2期273-280,共8页Peng Zhang Jin-Song Gong Zhi-Hao Xie Chang Su Xiao-Mei Zhang Zhi-Ming Rao Zheng-Hong Xu Jin-Song Shi 
supported by the National Key Research and Development Program of China(No.2021YFC2100900);the National Natural Science Foundation of China(No.32171261);the Natural Science Foundation of Jiangsu Province(No.BK20221082);the Fundamental Research Funds for the Central Universities(No.JUSRP21940).
Phospholipase D(PLD)is an essential biocatalyst for the biological production of phosphatidylserine and phospholipid modification.However,the efficient heterologous expression of PLD is limited by its cell toxicity.In...
关键词:Phospholipase D Secretion expression Bacillus subtilis BIOSYNTHESIS Enzymatic PLs modification 
Development of an Antarctic krill oil based self-microemulsion drug delivery system and its enhancement of bioaccessibility for curcumin被引量:1
《Food Bioscience》2023年第3期2330-2339,共10页Dong-wen Fu Ye Tian Zi-han Wang Jin-zhe Li Da-yong Zhou Bei-wei Zhu Liang Song 
financially supported by Key Program of National Natural Science Foundation of China(Grant No.32230080);Dalian Science and Technology Innovation Fund(Grant No.2022JJ11CG008);National Key R&D Program of China,grant number(Grant No.2018YFC1406806).
Self-microemulsion drug delivery systems(SMEDDS)have great potential for use in food applications,but their adoption has been limited due to the high proportion of non-edible surfactants.To address this limitation,we ...
关键词:Phospholipid reverse micelle ORGANOGELS Self-microemulsifying drug delivery systems MICROEMULSION CURCUMIN BIOACCESSIBILITY 
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