supported by the National Key Research and Development Program of China(2020YFA0908200);the National Natural Science Foundation of China(T2225003,52073060,and 61927805);the Nanjing Medical Science and Technique Development Foundation(ZKX21019);the Clinical Trials from Nanjing Drum Tower Hospital(2022-LCYJ-ZD-01);the Guangdong Basic and Applied Basic Research Foundation(2021B1515120054);the Shenzhen Fundamental Research Program(JCYJ20190813152616459 and JCYJ20210324133214038).
Microparticles have demonstrated value for regenerative medicine.Attempts in this field tend to focus on the development of intelligent multifunctional microparticles for tissue regeneration.Here,inspired by erythrocy...
reviewed and approved by the Institutional Review Board of Zhejiang Provincial People’s Hospital(Approval No.2023-338).
BACKGROUND Colon cancer is one of the most common malignant tumors of the digestive system.Liver metastasis after colon cancer surgery is the primary cause of death in patients with colon cancer.AIM To construct a nov...
supported by 2023 Kunshan Science and Technology Association youth science and technology talent lifting project(Project name:Mechanism study of mechanical damage of coagulation factor VWF based on in vitro blood-shearing experimental platform).
Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dyn...
Pneumonia, a respiratory infection induces acute or chronic inflammation, characterized by increased activity of lymphocytes and neutrophils, thus generating oxygen-free radicals that decrease the endogenous antioxida...
The interaction of pulsed electromagnetic fields (PEMF) with the human body may result in a variety of positive outcomes including analgesia, enhanced healing, chondroprotection, cognitive improvement and better quali...
supported in part by grants from the National Natural Science Foundation of China (81973993);Zhejiang Provincial Natural Science Foundation of China (LR20C070001).
Dear Editor,Red blood cells(RBCs)are the most abundant cells in the human body.RBCs have been widely investigated as in vivo drug delivery systems due to their unique biological properties.
Objective:Red blood cells are the predominant blood cell component utilized in transfusion therapy.Nevertheless,prolonged storage and the buildup of metabolites can lead to alterations in the structure and function of...
Supported by Project of Shanxi Provincial Health Commission,No.2021144.
BACKGROUND Erythrocyte alloantibodies are mainly produced after immune stimulation,such as blood transfusion,pregnancy,and transplantation,and are the leading causes of severe hemolytic transfusion reactions and diffi...
Supported by Grant-in-Aid for Scientific Research of Japan(KAKENHI),No.2459154;and No.15K09639。
BACKGROUND Numerous reports have demonstrated that the pathophysiology of graft-versushost disease(GVHD)during hematopoietic stem cell transplantation(HSCT)is closely related to vascular endothelial disorders and coag...